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Items: 1 to 20 of 98

1.

Blood gene expression signatures predict exposure levels.

Bushel PR, Heinloth AN, Li J, Huang L, Chou JW, Boorman GA, Malarkey DE, Houle CD, Ward SM, Wilson RE, Fannin RD, Russo MW, Watkins PB, Tennant RW, Paules RS.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18211-6. Epub 2007 Nov 2.

2.

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

Heinloth AN, Irwin RD, Boorman GA, Nettesheim P, Fannin RD, Sieber SO, Snell ML, Tucker CJ, Li L, Travlos GS, Vansant G, Blackshear PE, Tennant RW, Cunningham ML, Paules RS.

Toxicol Sci. 2004 Jul;80(1):193-202. Epub 2004 Apr 14.

3.

Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity.

McGill MR, Williams CD, Xie Y, Ramachandran A, Jaeschke H.

Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23.

4.

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice.

Zaher H, Buters JT, Ward JM, Bruno MK, Lucas AM, Stern ST, Cohen SD, Gonzalez FJ.

Toxicol Appl Pharmacol. 1998 Sep;152(1):193-9.

PMID:
9772215
5.

Acute exposure to ozone exacerbates acetaminophen-induced liver injury in mice.

Aibo DI, Birmingham NP, Lewandowski R, Maddox JF, Roth RA, Ganey PE, Wagner JG, Harkema JR.

Toxicol Sci. 2010 May;115(1):267-85. doi: 10.1093/toxsci/kfq034. Epub 2010 Feb 1.

6.

Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver.

Powell CL, Kosyk O, Ross PK, Schoonhoven R, Boysen G, Swenberg JA, Heinloth AN, Boorman GA, Cunningham ML, Paules RS, Rusyn I.

Toxicol Sci. 2006 Sep;93(1):213-22. Epub 2006 Jun 2.

7.

Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity.

Yang X, Greenhaw J, Shi Q, Su Z, Qian F, Davis K, Mendrick DL, Salminen WF.

Toxicol Sci. 2012 Feb;125(2):335-44. doi: 10.1093/toxsci/kfr321. Epub 2011 Nov 22.

8.

Effects of acetaminophen on hepatic gene expression in mice.

Jeong SY, Lim JS, Park HJ, Cho JW, Rana SV, Yoon S.

Physiol Chem Phys Med NMR. 2006;38(2):77-83.

PMID:
18472468
9.

Genotoxicity of 1,3-butadiene and its epoxy intermediates.

Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF; Health Review Committee.

Res Rep Health Eff Inst. 2009 Aug;(144):3-79.

PMID:
20017413
10.

Protective effect of Baccharis trimera extract on acute hepatic injury in a model of inflammation induced by acetaminophen.

Pádua Bda C, Rossoni Júnior JV, Magalhães CL, Chaves MM, Silva ME, Pedrosa ML, de Souza GH, Brandão GC, Rodrigues IV, Lima WG, Costa DC.

Mediators Inflamm. 2014;2014:196598. doi: 10.1155/2014/196598. Epub 2014 Nov 12.

11.

Hepatotoxicity of acetaminophen and N-acetyl-p-benzoquinone imine and enhancement by fructose.

Hojo M, Hanioka K, Miyata M, Yamazoe Y.

Xenobiotica. 2000 Sep;30(9):933-41.

PMID:
11055270
12.

Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse.

Steinebrunner N, Mogler C, Vittas S, Hoyler B, Sandig C, Stremmel W, Eisenbach C.

BMC Gastroenterol. 2014 Aug 19;14:148. doi: 10.1186/1471-230X-14-148.

13.

The protective effects of ozone therapy in a rat model of acetaminophen-induced liver injury.

Gul H, Uysal B, Cakir E, Yaman H, Macit E, Yildirim AO, Eyi YE, Kaldirim U, Oztas E, Akgul EO, Cayci T, Ozler M, Topal T, Oter S, Korkmaz A, Toygar M, Demirbag S.

Environ Toxicol Pharmacol. 2012 Jul;34(1):81-6. doi: 10.1016/j.etap.2012.02.006. Epub 2012 Mar 3.

PMID:
22459800
14.
15.

Influence of acetaminophen vehicle on regulation of transporter gene expression during hepatotoxicity.

Aleksunes LM, Augustine LM, Cherrington NJ, Manautou JE.

J Toxicol Environ Health A. 2007 Nov;70(21):1870-2.

PMID:
17934960
16.

Transcriptional profiling of the left and median liver lobes of male f344/n rats following exposure to acetaminophen.

Irwin RD, Parker JS, Lobenhofer EK, Burka LT, Blackshear PE, Vallant MK, Lebetkin EH, Gerken DF, Boorman GA.

Toxicol Pathol. 2005;33(1):111-7.

17.
18.

Effect of S-methylisothiourea in acetaminophen-induced hepatotoxicity in rat.

More AS, Kumari RR, Gupta G, Kathirvel K, Lonare MK, Dhayagude RS, Kumar D, Kumar D, Sharma AK, Tandan SK.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Nov;385(11):1127-39. doi: 10.1007/s00210-012-0789-0. Epub 2012 Aug 11.

PMID:
22885820
19.

Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2.

Aleksunes LM, Slitt AL, Maher JM, Augustine LM, Goedken MJ, Chan JY, Cherrington NJ, Klaassen CD, Manautou JE.

Toxicol Appl Pharmacol. 2008 Jan 1;226(1):74-83. Epub 2007 Aug 31.

20.
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