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Items: 1 to 20 of 92


Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase.

Futami K, Kumagai E, Makino H, Goto H, Takagi M, Shimamoto A, Furuichi Y.

Cancer Sci. 2008 Jan;99(1):71-80. Epub 2007 Oct 22.


Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models.

Futami K, Kumagai E, Makino H, Sato A, Takagi M, Shimamoto A, Furuichi Y.

Cancer Sci. 2008 Jun;99(6):1227-36. doi: 10.1111/j.1349-7006.2008.00794.x. Epub 2008 Apr 14.


RecQL1 DNA repair helicase: A potential tumor marker and therapeutic target against hepatocellular carcinoma.

Futami K, Ogasawara S, Goto H, Yano H, Furuichi Y.

Int J Mol Med. 2010 Apr;25(4):537-45.


Increased chemotherapeutic activity of camptothecin in cancer cells by siRNA-induced silencing of WRN helicase.

Futami K, Takagi M, Shimamoto A, Sugimoto M, Furuichi Y.

Biol Pharm Bull. 2007 Oct;30(10):1958-61.


RECQL1 and WRN proteins are potential therapeutic targets in head and neck squamous cell carcinoma.

Arai A, Chano T, Futami K, Furuichi Y, Ikebuchi K, Inui T, Tameno H, Ochi Y, Shimada T, Hisa Y, Okabe H.

Cancer Res. 2011 Jul 1;71(13):4598-607. doi: 10.1158/0008-5472.CAN-11-0320. Epub 2011 May 13.


RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers.

Futami K, Furuichi Y.

Front Genet. 2015 Jan 9;5:441. doi: 10.3389/fgene.2014.00441. eCollection 2014. Review.


RECQL1 plays an important role in the development of tongue squamous cell carcinoma.

Tao J, Tao S, Han J, Zhou Z, Zhang X, Wang H, Chen R, Ji F, Zhu Y.

Cell Physiol Biochem. 2014;33(5):1579-90. doi: 10.1159/000358721. Epub 2014 May 16.


RECQL1 DNA repair helicase: a potential therapeutic target and a proliferative marker against ovarian cancer.

Sanada S, Futami K, Terada A, Yonemoto K, Ogasawara S, Akiba J, Yasumoto M, Sumi A, Ushijima K, Kamura T, Furuichi Y, Yano H.

PLoS One. 2013 Aug 9;8(8):e72820. doi: 10.1371/journal.pone.0072820. eCollection 2013.


Tumor cell dependence on Ran-GTP-directed mitosis.

Xia F, Lee CW, Altieri DC.

Cancer Res. 2008 Mar 15;68(6):1826-33. doi: 10.1158/0008-5472.CAN-07-5279.


RNA interference-mediated silencing of mitotic kinesin KIF14 disrupts cell cycle progression and induces cytokinesis failure.

Carleton M, Mao M, Biery M, Warrener P, Kim S, Buser C, Marshall CG, Fernandes C, Annis J, Linsley PS.

Mol Cell Biol. 2006 May;26(10):3853-63.


Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents.

Nitta M, Kobayashi O, Honda S, Hirota T, Kuninaka S, Marumoto T, Ushio Y, Saya H.

Oncogene. 2004 Aug 26;23(39):6548-58.


Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis.

Hubbard K, Catalano J, Puri RK, Gnatt A.

BMC Cancer. 2008 May 12;8:133. doi: 10.1186/1471-2407-8-133.


Novel DNA damage checkpoint in mitosis: Mitotic DNA damage induces re-replication without cell division in various cancer cells.

Hyun SY, Rosen EM, Jang YJ.

Biochem Biophys Res Commun. 2012 Jul 6;423(3):593-9. doi: 10.1016/j.bbrc.2012.06.023. Epub 2012 Jun 13.


[Human RAD51 recombinase: the role in the cell cycle checkpoint and cellular survival].

Shtam TA, Varfolomeeva IIu, Semenova EV, Filatov MV.

Tsitologiia. 2008;50(11):958-63. Russian.


Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.

Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T.

Cancer Sci. 2008 Jan;99(1):62-70. Epub 2007 Oct 18.


Mitotic cell death by chromosome fragmentation.

Stevens JB, Liu G, Bremer SW, Ye KJ, Xu W, Xu J, Sun Y, Wu GS, Savasan S, Krawetz SA, Ye CJ, Heng HH.

Cancer Res. 2007 Aug 15;67(16):7686-94.


DNA helicases as targets for anti-cancer drugs.

Sharma S, Doherty KM, Brosh RM Jr.

Curr Med Chem Anticancer Agents. 2005 May;5(3):183-99. Review.


TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells.

Kim M, Liao J, Dowling ML, Voong KR, Parker SE, Wang S, El-Deiry WS, Kao GD.

Cancer Res. 2008 May 1;68(9):3440-9. doi: 10.1158/0008-5472.CAN-08-0014.


Different S/M checkpoint responses of tumor and non tumor cell lines to DNA replication inhibition.

Rodríguez-Bravo V, Guaita-Esteruelas S, Salvador N, Bachs O, Agell N.

Cancer Res. 2007 Dec 15;67(24):11648-56.


Role for the Werner syndrome protein in the promotion of tumor cell growth.

Opresko PL, Calvo JP, von Kobbe C.

Mech Ageing Dev. 2007 Jul-Aug;128(7-8):423-36. Epub 2007 May 31.

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