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Results: 1 to 20 of 188

1.

Network analysis of oncogenic Ras activation in cancer.

Stites EC, Trampont PC, Ma Z, Ravichandran KS.

Science. 2007 Oct 19;318(5849):463-7.

PMID:
17947584
[PubMed - indexed for MEDLINE]
Free Article
2.

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.

Scheffzek K, Ahmadian MR, Kabsch W, Wiesmüller L, Lautwein A, Schmitz F, Wittinghofer A.

Science. 1997 Jul 18;277(5324):333-8.

PMID:
9219684
[PubMed - indexed for MEDLINE]
Free Article
3.

Guanosine triphosphatase stimulation of oncogenic Ras mutants.

Ahmadian MR, Zor T, Vogt D, Kabsch W, Selinger Z, Wittinghofer A, Scheffzek K.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7065-70.

PMID:
10359839
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Specific biochemical inactivation of oncogenic Ras proteins by nucleoside diphosphate kinase.

Fischbach MA, Settleman J.

Cancer Res. 2003 Jul 15;63(14):4089-94.

PMID:
12874011
[PubMed - indexed for MEDLINE]
Free Article
5.

p200 RhoGAP promotes cell proliferation by mediating cross-talk between Ras and Rho signaling pathways.

Shang X, Moon SY, Zheng Y.

J Biol Chem. 2007 Mar 23;282(12):8801-11. Epub 2007 Feb 1.

PMID:
17272280
[PubMed - indexed for MEDLINE]
Free Article
6.

There are GAPS and there are GAPS.

Iyengar R.

Science. 1997 Jan 3;275(5296):42-3. No abstract available.

PMID:
8999536
[PubMed - indexed for MEDLINE]
7.

Signal processing at the Ras circuit: what shapes Ras activation patterns?

Markevich NI, Moehren G, Demin OV, Kiyatkin A, Hoek JB, Kholodenko BN.

Syst Biol (Stevenage). 2004 Jun;1(1):104-13.

PMID:
17052120
[PubMed - indexed for MEDLINE]
8.

Co-ordination and specificity of the action of GTPase-activating proteins and GDP/GTP-exchange factors on Ras.

Parrini MC, Giglione C, Parmeggiani A.

Biochem Soc Trans. 1997 Aug;25(3):997-1001. Review. No abstract available.

PMID:
9388589
[PubMed - indexed for MEDLINE]
9.

Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation.

Konishi H, Karakas B, Abukhdeir AM, Lauring J, Gustin JP, Garay JP, Konishi Y, Gallmeier E, Bachman KE, Park BH.

Cancer Res. 2007 Sep 15;67(18):8460-7.

PMID:
17875684
[PubMed - indexed for MEDLINE]
Free Article
10.

Perturbation of the conformational equilibria in Ras by selective mutations as studied by 31P NMR spectroscopy.

Spoerner M, Wittinghofer A, Kalbitzer HR.

FEBS Lett. 2004 Dec 17;578(3):305-10.

PMID:
15589837
[PubMed - indexed for MEDLINE]
Free Article
11.

Intrinsic and GTPase-activating protein-stimulated Ras GTPase assays.

Bollag G, McCormick F.

Methods Enzymol. 1995;255:161-70. No abstract available.

PMID:
8524100
[PubMed - indexed for MEDLINE]
12.

Targeting RAS signalling pathways in cancer therapy.

Downward J.

Nat Rev Cancer. 2003 Jan;3(1):11-22. Review.

PMID:
12509763
[PubMed - indexed for MEDLINE]
13.

Control of Ras cycling by Ca2+.

Walker SA, Cullen PJ, Taylor JA, Lockyer PJ.

FEBS Lett. 2003 Jul 3;546(1):6-10. Review.

PMID:
12829229
[PubMed - indexed for MEDLINE]
14.

Tailoring Ras-pathway--inhibitor combinations for cancer therapy.

Blum R, Kloog Y.

Drug Resist Updat. 2005 Dec;8(6):369-80. Epub 2005 Dec 13. Review.

PMID:
16356760
[PubMed - indexed for MEDLINE]
15.
16.

The impact of the regulatory design on the response of epidermal growth factor receptor-mediated signal transduction towards oncogenic mutations.

Wolf J, Dronov S, Tobin F, Goryanin I.

FEBS J. 2007 Nov;274(21):5505-17. Epub 2007 Oct 4.

PMID:
17916191
[PubMed - indexed for MEDLINE]
17.

Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras.

Vasudevan KM, Burikhanov R, Goswami A, Rangnekar VM.

Cancer Res. 2007 Nov 1;67(21):10343-50.

PMID:
17974977
[PubMed - indexed for MEDLINE]
Free Article
18.

TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.

Oberst MD, Beberman SJ, Zhao L, Yin JJ, Ward Y, Kelly K.

BMC Cancer. 2008 Jul 2;8:189. doi: 10.1186/1471-2407-8-189.

PMID:
18597688
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The Ras GDP/GTP cycle is regulated by oxidizing agents at the level of Ras regulators and effectors.

Accorsi K, Giglione C, Vanoni M, Parmeggiani A.

FEBS Lett. 2001 Mar 9;492(1-2):139-45.

PMID:
11248252
[PubMed - indexed for MEDLINE]
Free Article
20.

Mechanisms of signal transduction by Ras.

Bar-Sagi D.

Semin Cell Biol. 1992 Apr;3(2):93-8. Review.

PMID:
1611045
[PubMed - indexed for MEDLINE]
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