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Results: 1 to 20 of 216

1.

PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function.

Kaneto H, Miyatsuka T, Kawamori D, Yamamoto K, Kato K, Shiraiwa T, Katakami N, Yamasaki Y, Matsuhisa M, Matsuoka TA.

Endocr J. 2008 May;55(2):235-52. Epub 2007 Oct 15. Review.

PMID:
17938503
[PubMed - indexed for MEDLINE]
Free Article
2.

Crucial role of PDX-1 in pancreas development, beta-cell differentiation, and induction of surrogate beta-cells.

Kaneto H, Miyatsuka T, Shiraiwa T, Yamamoto K, Kato K, Fujitani Y, Matsuoka TA.

Curr Med Chem. 2007;14(16):1745-52. Review.

PMID:
17627512
[PubMed - indexed for MEDLINE]
3.

Role of PDX-1 and MafA as a potential therapeutic target for diabetes.

Kaneto H, Miyatsuka T, Fujitani Y, Noguchi H, Song KH, Yoon KH, Matsuoka TA.

Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S127-37. Epub 2007 Apr 20. Review.

PMID:
17449132
[PubMed - indexed for MEDLINE]
4.

PDX-1 functions as a master factor in the pancreas.

Kaneto H, Matsuoka TA, Miyatsuka T, Kawamori D, Katakami N, Yamasaki Y, Matsuhisa M.

Front Biosci. 2008 May 1;13:6406-20. Review.

PMID:
18508668
[PubMed - indexed for MEDLINE]
5.

Glucose regulation of insulin gene expression in pancreatic beta-cells.

Andrali SS, Sampley ML, Vanderford NL, Ozcan S.

Biochem J. 2008 Oct 1;415(1):1-10. doi: 10.1042/BJ20081029. Review.

PMID:
18778246
[PubMed - indexed for MEDLINE]
6.

Role of MafA in pancreatic beta-cells.

Kaneto H, Matsuoka TA, Kawashima S, Yamamoto K, Kato K, Miyatsuka T, Katakami N, Matsuhisa M.

Adv Drug Deliv Rev. 2009 Jul 2;61(7-8):489-96. doi: 10.1016/j.addr.2008.12.015. Epub 2009 Apr 22. Review.

PMID:
19393272
[PubMed - indexed for MEDLINE]
7.

Combination of MafA, PDX-1 and NeuroD is a useful tool to efficiently induce insulin-producing surrogate beta-cells.

Kaneto H, Matsuoka TA, Katakami N, Matsuhisa M.

Curr Med Chem. 2009;16(24):3144-51. Review.

PMID:
19689288
[PubMed - indexed for MEDLINE]
8.

Pleiotropic Roles of PDX-1 in the Pancreas.

Kaneto H, Miyatsuka T, Kawamori D, Matsuoka TA.

Rev Diabet Stud. 2007 Winter;4(4):209-25. doi: 10.1900/RDS.2007.4.209. Epub 2008 Feb 10.

PMID:
18338074
[PubMed]
Free PMC Article
9.

A crucial role of MafA as a novel therapeutic target for diabetes.

Kaneto H, Matsuoka TA, Nakatani Y, Miyatsuka T, Matsuhisa M, Hori M, Yamasaki Y.

J Biol Chem. 2005 Apr 15;280(15):15047-52. Epub 2005 Jan 20.

PMID:
15664997
[PubMed - indexed for MEDLINE]
Free Article
10.

Roles and regulation of transcription factor MafA in islet beta-cells.

Aramata S, Han SI, Kataoka K.

Endocr J. 2007 Dec;54(5):659-66. Epub 2007 Aug 30. Review.

PMID:
17785922
[PubMed - indexed for MEDLINE]
Free Article
11.

PDX-1 and the pancreas.

Ashizawa S, Brunicardi FC, Wang XP.

Pancreas. 2004 Mar;28(2):109-20. Review.

PMID:
15028942
[PubMed - indexed for MEDLINE]
12.

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.

Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R.

Mol Cell Biol. 2006 Aug;26(15):5735-43.

PMID:
16847327
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells.

Harmon JS, Stein R, Robertson RP.

J Biol Chem. 2005 Mar 25;280(12):11107-13. Epub 2005 Jan 20.

PMID:
15664999
[PubMed - indexed for MEDLINE]
Free Article
14.

Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter.

Docherty HM, Hay CW, Ferguson LA, Barrow J, Durward E, Docherty K.

Biochem J. 2005 Aug 1;389(Pt 3):813-20.

PMID:
15862113
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene.

Kataoka K, Han SI, Shioda S, Hirai M, Nishizawa M, Handa H.

J Biol Chem. 2002 Dec 20;277(51):49903-10. Epub 2002 Oct 3.

PMID:
12368292
[PubMed - indexed for MEDLINE]
Free Article
16.

Regulation of the pancreatic duodenal homeobox-1 protein by DNA-dependent protein kinase.

Lebrun P, Montminy MR, Van Obberghen E.

J Biol Chem. 2005 Nov 18;280(46):38203-10. Epub 2005 Sep 15.

PMID:
16166097
[PubMed - indexed for MEDLINE]
Free Article
17.

Pancreatic Duodenal Homeobox (PDX-1) in health and disease.

Melloul D, Tsur A, Zangen D.

J Pediatr Endocrinol Metab. 2002 Nov-Dec;15(9):1461-72. Review.

PMID:
12503852
[PubMed - indexed for MEDLINE]
18.

A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells.

Nishimura W, Kondo T, Salameh T, El Khattabi I, Dodge R, Bonner-Weir S, Sharma A.

Dev Biol. 2006 May 15;293(2):526-39. Epub 2006 Apr 3.

PMID:
16580660
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Conversion of immortal liver progenitor cells into pancreatic endocrine progenitor cells by persistent expression of Pdx-1.

Jin CX, Li WL, Xu F, Geng ZH, He ZY, Su J, Tao XR, Ding XY, Wang X, Hu YP.

J Cell Biochem. 2008 May 1;104(1):224-36.

PMID:
17979180
[PubMed - indexed for MEDLINE]
20.

MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.

Ye DZ, Tai MH, Linning KD, Szabo C, Olson LK.

Diabetes. 2006 Mar;55(3):742-50.

PMID:
16505238
[PubMed - indexed for MEDLINE]
Free Article

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