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Items: 1 to 20 of 122

1.

Mechanisms of cytochrome P450 induction.

Tompkins LM, Wallace AD.

J Biochem Mol Toxicol. 2007;21(4):176-81. Review.

PMID:
17936931
2.

The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.

Sugatani J, Yamakawa K, Tonda E, Nishitani S, Yoshinari K, Degawa M, Abe I, Noguchi H, Miwa M.

Biochem Pharmacol. 2004 Mar 1;67(5):989-1000. Erratum in: Biochem Pharmacol. 2004 Jun 15;67(12):2991-2.

PMID:
15104253
3.

PXR, CAR and drug metabolism.

Willson TM, Kliewer SA.

Nat Rev Drug Discov. 2002 Apr;1(4):259-66. Review.

PMID:
12120277
4.

Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.

Wang H, LeCluyse EL.

Clin Pharmacokinet. 2003;42(15):1331-57. Review.

PMID:
14674787
5.

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA.

Mol Pharmacol. 2002 Sep;62(3):638-46.

7.
8.

Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.

Rhodes SP, Otten JN, Hingorani GP, Hartley DP, Franklin RB.

J Pharmacol Toxicol Methods. 2011 May-Jun;63(3):223-6. doi: 10.1016/j.vascn.2010.11.002. Epub 2010 Nov 24.

PMID:
21111054
9.

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.

Moore LB, Parks DJ, Jones SA, Bledsoe RK, Consler TG, Stimmel JB, Goodwin B, Liddle C, Blanchard SG, Willson TM, Collins JL, Kliewer SA.

J Biol Chem. 2000 May 19;275(20):15122-7.

10.

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB.

Nat Med. 2003 Feb;9(2):220-4. Epub 2003 Jan 6.

PMID:
12514743
11.

Induction of phase I, II and III drug metabolism/transport by xenobiotics.

Xu C, Li CY, Kong AN.

Arch Pharm Res. 2005 Mar;28(3):249-68. Review.

PMID:
15832810
12.

Expression alterations of cytochromes P4501A1, 2E1, and 3A, and their receptors AhR and PXR caused by 1-octyl-3-methylimidazolium chloride in mouse mammary carcinoma cells.

Li X, Ma J, Jing C, Wang J.

Chemosphere. 2013 Nov;93(10):2488-92. doi: 10.1016/j.chemosphere.2013.08.092. Epub 2013 Oct 1.

PMID:
24094773
13.

Regulation of cyp3a gene transcription by the pregnane x receptor.

Goodwin B, Redinbo MR, Kliewer SA.

Annu Rev Pharmacol Toxicol. 2002;42:1-23. Review.

PMID:
11807162
14.
15.

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.

Zhang J, Huang W, Qatanani M, Evans RM, Moore DD.

J Biol Chem. 2004 Nov 19;279(47):49517-22. Epub 2004 Sep 8.

16.

Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.

Faucette SR, Sueyoshi T, Smith CM, Negishi M, Lecluyse EL, Wang H.

J Pharmacol Exp Ther. 2006 Jun;317(3):1200-9. Epub 2006 Mar 2.

17.

Up-regulation of CYP expression in hepatoma cells stably transfected by chimeric nuclear receptors.

K├╝blbeck J, Reinisalo M, Mustonen R, Honkakoski P.

Eur J Pharm Sci. 2010 Jul 11;40(4):263-72. doi: 10.1016/j.ejps.2010.03.022. Epub 2010 Apr 8.

PMID:
20381613
18.

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.

Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB Jr, Kliewer SA, Gonzalez FJ, Sinal CJ.

J Biol Chem. 2003 Nov 14;278(46):45062-71. Epub 2003 Aug 15.

19.

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.

Faucette SR, Zhang TC, Moore R, Sueyoshi T, Omiecinski CJ, LeCluyse EL, Negishi M, Wang H.

J Pharmacol Exp Ther. 2007 Jan;320(1):72-80. Epub 2006 Oct 13.

20.

The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.

Pascussi JM, Gerbal-Chaloin S, Drocourt L, Maurel P, Vilarem MJ.

Biochim Biophys Acta. 2003 Feb 17;1619(3):243-53. Review.

PMID:
12573484
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