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Results: 1 to 20 of 95

Similar articles for PubMed (Select 17921190)

2.

Blockade of 11β-hydroxysteroid dehydrogenase type 1 enzyme inhibits experimental collagenase-induced osteoarthritis.

Li F, Qiao C, Li Y, Zhu J, Chen J, Guo S.

Mol Med Rep. 2015 Mar;11(3):2071-5. doi: 10.3892/mmr.2014.2983. Epub 2014 Nov 19.

PMID:
25412149
3.

11β-Hydroxysteroid dehydrogenase activity in the brain does not contribute to systemic interconversion of cortisol and cortisone in healthy men.

Kilgour AH, Semple S, Marshall I, Andrews P, Andrew R, Walker BR.

J Clin Endocrinol Metab. 2015 Feb;100(2):483-9. doi: 10.1210/jc.2014-3277. Epub 2014 Nov 13.

4.

Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

Gillespie P, Pietranico-Cole S, Myers M, Bilotta JA, Conde-Knape K, Fotouhi N, Goodnow RA Jr, Guertin KR, Hamilton MM, Haynes NE, Liu B, Qi L, Ren Y, Scott NR, So SS, Spence C, Taub R, Thakkar K, Tilley JW, Zwingelstein C.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2707-11. doi: 10.1016/j.bmcl.2014.04.049. Epub 2014 Apr 21.

PMID:
24815509
5.

Tissue-specific dysregulation of cortisol regeneration by 11βHSD1 in obesity: has it promised too much?

Stomby A, Andrew R, Walker BR, Olsson T.

Diabetologia. 2014 Jun;57(6):1100-10. doi: 10.1007/s00125-014-3228-6. Epub 2014 Apr 8. Review.

PMID:
24710966
6.

Increased skeletal muscle 11βHSD1 mRNA is associated with lower muscle strength in ageing.

Kilgour AH, Gallagher IJ, MacLullich AM, Andrew R, Gray CD, Hyde P, Wackerhage H, Husi H, Ross JA, Starr JM, Chapman KE, Fearon KC, Walker BR, Greig CA.

PLoS One. 2013 Dec 31;8(12):e84057. doi: 10.1371/journal.pone.0084057. eCollection 2013.

7.

Peripheral and central nervous system inhibition of 11β-hydroxysteroid dehydrogenase type 1 in man by the novel inhibitor ABT-384.

Katz DA, Liu W, Locke C, Jacobson P, Barnes DM, Basu R, An G, Rieser MJ, Daszkowski D, Groves F, Heneghan G, Shah A, Gevorkyan H, Jhee SS, Ereshefsky L, Marek GJ.

Transl Psychiatry. 2013 Aug 27;3:e295. doi: 10.1038/tp.2013.67.

8.

Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects.

Wright DH, Stone JA, Crumley TM, Wenning L, Zheng W, Yan K, Yang AY, Sun L, Cilissen C, Ramael S, Hermanowski-Vosatka A, Langdon RB, Gottesdiener KM, Wagner JA, Lai E.

Br J Clin Pharmacol. 2013 Dec;76(6):917-31. doi: 10.1111/bcp.12131.

9.

Inhibition of microsomal cortisol production by (-)-epigallocatechin-3-gallate through a redox shift in the endoplasmic reticulum--a potential new target for treating obesity-related diseases.

Szelényi P, Révész K, Konta L, Tüttõ A, Mandl J, Kereszturi É, Csala M.

Biofactors. 2013 Sep-Oct;39(5):534-41. doi: 10.1002/biof.1095. Epub 2013 Mar 29.

PMID:
23554216
10.

N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: strategies to eliminate reactive metabolites.

Nair SK, Matthews JJ, Cripps SJ, Cheng H, Hoffman JE, Smith C, Kupchinsky S, Siu M, Taylor WD, Wang Y, Johnson TO, Dress KR, Edwards MP, Zhou S, Hosea NA, Lapaglia A, Kang P, Castro A, Ermolieff J, Fanjul A, Vogel JE, Rejto P, Dalvie D.

Bioorg Med Chem Lett. 2013 Apr 15;23(8):2344-8. doi: 10.1016/j.bmcl.2013.02.066. Epub 2013 Feb 24.

PMID:
23489629
11.

11β-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoE⁻/⁻ mice.

García RA, Search DJ, Lupisella JA, Ostrowski J, Guan B, Chen J, Yang WP, Truong A, He A, Zhang R, Yan M, Hellings SE, Gargalovic PS, Ryan CS, Watson LM, Langish RA, Shipkova PA, Carson NL, Taylor JR, Yang R, Psaltis GC, Harrity TW, Robl JA, Gordon DA.

PLoS One. 2013;8(2):e53192. doi: 10.1371/journal.pone.0053192. Epub 2013 Feb 1.

12.
13.

IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response.

Josephson MB, Jiao J, Xu S, Hu A, Paranjape C, Grunstein JS, Grumbach Y, Nino G, Kreiger PA, McDonough J, Grunstein MM.

Am J Physiol Lung Cell Mol Physiol. 2012 Sep;303(5):L382-90. doi: 10.1152/ajplung.00125.2012. Epub 2012 Jul 6.

14.

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.

Park JS, Rhee SD, Jung WH, Kang NS, Kim HY, Kang SK, Ahn JH, Kim KY.

Eur J Pharmacol. 2012 Sep 15;691(1-3):19-27. doi: 10.1016/j.ejphar.2012.06.024. Epub 2012 Jul 1.

PMID:
22760069
15.

11beta-Hydroxysteroid dehydrogenase type 1 inhibitors: novel agents for the treatment of metabolic syndrome and obesity-related disorders?

Anagnostis P, Katsiki N, Adamidou F, Athyros VG, Karagiannis A, Kita M, Mikhailidis DP.

Metabolism. 2013 Jan;62(1):21-33. doi: 10.1016/j.metabol.2012.05.002. Epub 2012 May 30. Review.

PMID:
22652056
16.

Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells.

Kratschmar DV, Calabrese D, Walsh J, Lister A, Birk J, Appenzeller-Herzog C, Moulin P, Goldring CE, Odermatt A.

PLoS One. 2012;7(5):e36774. doi: 10.1371/journal.pone.0036774. Epub 2012 May 11.

17.

Recycling between cortisol and cortisone in human splanchnic, subcutaneous adipose, and skeletal muscle tissues in vivo.

Hughes KA, Manolopoulos KN, Iqbal J, Cruden NL, Stimson RH, Reynolds RM, Newby DE, Andrew R, Karpe F, Walker BR.

Diabetes. 2012 Jun;61(6):1357-64. doi: 10.2337/db11-1345. Epub 2012 Apr 17.

18.

11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.

Pereira CD, Azevedo I, Monteiro R, Martins MJ.

Diabetes Obes Metab. 2012 Oct;14(10):869-81. doi: 10.1111/j.1463-1326.2012.01582.x. Epub 2012 Mar 8. Review.

PMID:
22321826
19.

Peroxisome proliferator-activated receptor-γ activation induces 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages.

Chinetti-Gbaguidi G, Bouhlel MA, Copin C, Duhem C, Derudas B, Neve B, Noel B, Eeckhoute J, Lefebvre P, Seckl JR, Staels B.

Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):677-85. doi: 10.1161/ATVBAHA.111.241364. Epub 2011 Dec 29.

20.

Piper sarmentosum prevents glucocorticoid-induced osteoporotic bone resorption by increasing 11β-hydroxysteroid dehydrogenase type 1 activity.

Suhana MR, Farihah HS, Faizah O, Nazrun SA, Norazlina M, Norliza M, Nirwana SI.

Clin Ter. 2011;162(4):313-8.

PMID:
21912818
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