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The HhH domain of the human DNA repair protein XPF forms stable homodimers.

Das D, Tripsianes K, Jaspers NG, Hoeijmakers JH, Kaptein R, Boelens R, Folkers GE.

Proteins. 2008 Mar;70(4):1551-63.


The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair.

Tripsianes K, Folkers G, Ab E, Das D, Odijk H, Jaspers NG, Hoeijmakers JH, Kaptein R, Boelens R.

Structure. 2005 Dec;13(12):1849-58.


Biophysical characterization of the interaction domains and mapping of the contact residues in the XPF-ERCC1 complex.

Choi YJ, Ryu KS, Ko YM, Chae YK, Pelton JG, Wemmer DE, Choi BS.

J Biol Chem. 2005 Aug 5;280(31):28644-52. Epub 2005 Jun 1.


Mapping of interaction domains between human repair proteins ERCC1 and XPF.

de Laat WL, Sijbers AM, Odijk H, Jaspers NG, Hoeijmakers JH.

Nucleic Acids Res. 1998 Sep 15;26(18):4146-52.


Domain mapping of the DNA binding, endonuclease, and ERCC1 binding properties of the human DNA repair protein XPF.

McCutchen-Maloney SL, Giannecchini CA, Hwang MH, Thelen MP.

Biochemistry. 1999 Jul 20;38(29):9417-25.


The structure of the XPF-ssDNA complex underscores the distinct roles of the XPF and ERCC1 helix- hairpin-helix domains in ss/ds DNA recognition.

Das D, Folkers GE, van Dijk M, Jaspers NG, Hoeijmakers JH, Kaptein R, Boelens R.

Structure. 2012 Apr 4;20(4):667-75. doi: 10.1016/j.str.2012.02.009. Epub 2012 Apr 3.


Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52.

Motycka TA, Bessho T, Post SM, Sung P, Tomkinson AE.

J Biol Chem. 2004 Apr 2;279(14):13634-9. Epub 2004 Jan 20.


Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.

Tsodikov OV, Enzlin JH, Schärer OD, Ellenberger T.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11236-41. Epub 2005 Aug 2.


Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair.

Su Y, Orelli B, Madireddy A, Niedernhofer LJ, Schärer OD.

J Biol Chem. 2012 Jun 22;287(26):21846-55. doi: 10.1074/jbc.M111.337899. Epub 2012 Apr 30.


Activity of individual ERCC1 and XPF subunits in DNA nucleotide excision repair.

Gaillard PH, Wood RD.

Nucleic Acids Res. 2001 Feb 15;29(4):872-9.


Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells.

Lan L, Hayashi T, Rabeya RM, Nakajima S, Kanno Si, Takao M, Matsunaga T, Yoshino M, Ichikawa M, Riele Ht, Tsuchiya S, Tanaka K, Yasui A.

DNA Repair (Amst). 2004 Feb 3;3(2):135-43.


Contribution of XPF functional domains to the 5' and 3' incisions produced at the site of a psoralen interstrand cross-link.

Kumaresan KR, Hwang M, Thelen MP, Lambert MW.

Biochemistry. 2002 Jan 22;41(3):890-6.


DNA structural elements required for ERCC1-XPF endonuclease activity.

de Laat WL, Appeldoorn E, Jaspers NG, Hoeijmakers JH.

J Biol Chem. 1998 Apr 3;273(14):7835-42.


The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex.

Faridounnia M, Wienk H, Kovačič L, Folkers GE, Jaspers NG, Kaptein R, Hoeijmakers JH, Boelens R.

J Biol Chem. 2015 Aug 14;290(33):20541-55. doi: 10.1074/jbc.M114.635169. Epub 2015 Jun 17.


Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex.

Bessho T, Sancar A, Thompson LH, Thelen MP.

J Biol Chem. 1997 Feb 7;272(6):3833-7.


XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening.

Wu Y, Zacal NJ, Rainbow AJ, Zhu XD.

DNA Repair (Amst). 2007 Feb 4;6(2):157-66. Epub 2006 Oct 18.


Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease.

Park CH, Bessho T, Matsunaga T, Sancar A.

J Biol Chem. 1995 Sep 29;270(39):22657-60.


Structure of an XPF endonuclease with and without DNA suggests a model for substrate recognition.

Newman M, Murray-Rust J, Lally J, Rudolf J, Fadden A, Knowles PP, White MF, McDonald NQ.

EMBO J. 2005 Mar 9;24(5):895-905. Epub 2005 Feb 17.

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