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Items: 1 to 20 of 146

1.

Protective effect of prion protein via the N-terminal region in mediating a protective effect on paraquat-induced oxidative injury in neuronal cells.

Dupiereux I, Falisse-Poirrier N, Zorzi W, Watt NT, Thellin O, Zorzi D, Pierard O, Hooper NM, Heinen E, Elmoualij B.

J Neurosci Res. 2008 Feb 15;86(3):653-9.

PMID:
17896796
2.

Insulin-like growth factor-1 protects against prion peptide-induced cell death in neuronal cells via inhibition of Bax translocation.

Park YG, Jeong JK, Moon MH, Lee JH, Lee YJ, Seol JW, Kim SJ, Kang SJ, Park SY.

Int J Mol Med. 2012 Nov;30(5):1069-74. doi: 10.3892/ijmm.2012.1087. Epub 2012 Aug 8.

PMID:
22895829
3.

Novel neuroprotective compound SCH-20148 rescues thymocytes and SH-SY5Y cells from thapsigargin-induced mitochondrial membrane potential reduction and cell death.

Muramatsu Y, Maemoto T, Iwashita A, Matsuoka N.

Eur J Pharmacol. 2007 Jun 1;563(1-3):40-8. Epub 2007 Feb 8.

PMID:
17343843
4.

Tethering the N-terminus of the prion protein compromises the cellular response to oxidative stress.

Zeng F, Watt NT, Walmsley AR, Hooper NM.

J Neurochem. 2003 Feb;84(3):480-90.

5.

Study on the toxic mechanism of prion protein peptide 106-126 in neuronal and non neuronal cells.

Dupiereux I, Zorzi W, Rachidi W, Zorzi D, Pierard O, Lhereux B, Heinen E, Elmoualij B.

J Neurosci Res. 2006 Aug 15;84(3):637-46.

PMID:
16786576
6.

Magnolol protects against oxidative stress-mediated neural cell damage by modulating mitochondrial dysfunction and PI3K/Akt signaling.

Dong L, Zhou S, Yang X, Chen Q, He Y, Huang W.

J Mol Neurosci. 2013 Jul;50(3):469-81. doi: 10.1007/s12031-013-9964-0. Epub 2013 Feb 14.

PMID:
23404573
7.
8.

Protective effects of riluzole on dopamine neurons: involvement of oxidative stress and cellular energy metabolism.

Storch A, Burkhardt K, Ludolph AC, Schwarz J.

J Neurochem. 2000 Dec;75(6):2259-69.

9.

Hypoxia-inducible factor-1 α regulates prion protein expression to protect against neuron cell damage.

Jeong JK, Seo JS, Moon MH, Lee YJ, Seol JW, Park SY.

Neurobiol Aging. 2012 May;33(5):1006.e1-10. doi: 10.1016/j.neurobiolaging.2011.09.037. Epub 2011 Oct 28.

PMID:
22036844
10.

The octarepeat region of prion protein, but not the TM1 domain, is important for the antioxidant effect of prion protein.

Malaisé M, Schätzl HM, Bürkle A.

Free Radic Biol Med. 2008 Dec 15;45(12):1622-30. doi: 10.1016/j.freeradbiomed.2008.08.024. Epub 2008 Sep 9.

PMID:
18824094
11.

Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis.

Singh A, Mohan ML, Isaac AO, Luo X, Petrak J, Vyoral D, Singh N.

PLoS One. 2009;4(2):e4468. doi: 10.1371/journal.pone.0004468. Epub 2009 Feb 12. Erratum in: PLoS ONE. 2009;4(2). doi: 10.1371/annotation/194f4e44-20f0-48eb-bbe9-14e21d18909b.

12.

Octapeptide repeat region of prion protein (PrP) is required at an early stage for production of abnormal prion protein in PrP-deficient neuronal cell line.

Sakudo A, Wu G, Onodera T, Ikuta K.

Biochem Biophys Res Commun. 2008 Jan 4;365(1):164-9. Epub 2007 Nov 5.

PMID:
17981146
13.

Salvianolic acid A protects human SH-SY5Y neuroblastoma cells against H₂O₂-induced injury by increasing stress tolerance ability.

Zhang HA, Gao M, Zhang L, Zhao Y, Shi LL, Chen BN, Wang YH, Wang SB, Du GH.

Biochem Biophys Res Commun. 2012 May 11;421(3):479-83. doi: 10.1016/j.bbrc.2012.04.021. Epub 2012 Apr 9.

PMID:
22516750
14.

Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity.

Jeong JK, Moon MH, Lee YJ, Seol JW, Park SY.

Neurobiol Aging. 2013 Jan;34(1):146-56. doi: 10.1016/j.neurobiolaging.2012.04.002. Epub 2012 May 9.

PMID:
22575359
15.

Reactive oxygen species-mediated beta-cleavage of the prion protein in the cellular response to oxidative stress.

Watt NT, Taylor DR, Gillott A, Thomas DA, Perera WS, Hooper NM.

J Biol Chem. 2005 Oct 28;280(43):35914-21. Epub 2005 Aug 24.

16.

Cellular prion protein modulates the intracellular calcium response to hydrogen peroxide.

Krebs B, Wiebelitz A, Balitzki-Korte B, Vassallo N, Paluch S, Mitteregger G, Onodera T, Kretzschmar HA, Herms J.

J Neurochem. 2007 Jan;100(2):358-67.

17.

Normal cellular prion protein protects against manganese-induced oxidative stress and apoptotic cell death.

Choi CJ, Anantharam V, Saetveit NJ, Houk RS, Kanthasamy A, Kanthasamy AG.

Toxicol Sci. 2007 Aug;98(2):495-509. Epub 2007 May 4.

18.

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

Hetz C, Russelakis-Carneiro M, Wälchli S, Carboni S, Vial-Knecht E, Maundrell K, Castilla J, Soto C.

J Neurosci. 2005 Mar 16;25(11):2793-802.

20.

Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein.

Nishida N, Harris DA, Vilette D, Laude H, Frobert Y, Grassi J, Casanova D, Milhavet O, Lehmann S.

J Virol. 2000 Jan;74(1):320-5.

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