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Results: 1 to 20 of 109

1.

The selectivity of protein kinase inhibitors: a further update.

Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, Cohen P.

Biochem J. 2007 Dec 15;408(3):297-315.

PMID:
17850214
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The specificities of protein kinase inhibitors: an update.

Bain J, McLauchlan H, Elliott M, Cohen P.

Biochem J. 2003 Apr 1;371(Pt 1):199-204.

PMID:
12534346
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.

Sapkota GP, Cummings L, Newell FS, Armstrong C, Bain J, Frodin M, Grauert M, Hoffmann M, Schnapp G, Steegmaier M, Cohen P, Alessi DR.

Biochem J. 2007 Jan 1;401(1):29-38.

PMID:
17040210
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

Meijer L, Borgne A, Mulner O, Chong JP, Blow JJ, Inagaki N, Inagaki M, Delcros JG, Moulinoux JP.

Eur J Biochem. 1997 Jan 15;243(1-2):527-36.

PMID:
9030781
[PubMed - indexed for MEDLINE]
Free Article
5.

Specificity and mechanism of action of some commonly used protein kinase inhibitors.

Davies SP, Reddy H, Caivano M, Cohen P.

Biochem J. 2000 Oct 1;351(Pt 1):95-105.

PMID:
10998351
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck.

Zhou HR, Jia Q, Pestka JJ.

Toxicol Sci. 2005 Jun;85(2):916-26. Epub 2005 Mar 16.

PMID:
15772366
[PubMed - indexed for MEDLINE]
Free Article
7.

Inhibiting Src family tyrosine kinase activity blocks glutamate signalling to ERK1/2 and Akt/PKB but not JNK in cultured striatal neurones.

Crossthwaite AJ, Valli H, Williams RJ.

J Neurochem. 2004 Mar;88(5):1127-39.

PMID:
15009668
[PubMed - indexed for MEDLINE]
8.

High glucose regulates cyclin D1/E of human mesenchymal stem cells through TGF-beta1 expression via Ca2+/PKC/MAPKs and PI3K/Akt/mTOR signal pathways.

Ryu JM, Lee MY, Yun SP, Han HJ.

J Cell Physiol. 2010 Jul;224(1):59-70. doi: 10.1002/jcp.22091.

PMID:
20232305
[PubMed - indexed for MEDLINE]
9.
11.

Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT(1)MF-2 cells.

Robinson AJ, Dickenson JM.

Eur J Pharmacol. 2001 Feb 16;413(2-3):151-61.

PMID:
11226388
[PubMed - indexed for MEDLINE]
12.

Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase.

Kumar S, Jiang MS, Adams JL, Lee JC.

Biochem Biophys Res Commun. 1999 Oct 5;263(3):825-31.

PMID:
10512765
[PubMed - indexed for MEDLINE]
13.

Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL.

Auld GC, Campbell DG, Morrice N, Cohen P.

Biochem J. 2005 Aug 1;389(Pt 3):775-83.

PMID:
15910284
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Structural basis for selective inhibition of Src family kinases by PP1.

Liu Y, Bishop A, Witucki L, Kraybill B, Shimizu E, Tsien J, Ubersax J, Blethrow J, Morgan DO, Shokat KM.

Chem Biol. 1999 Sep;6(9):671-8.

PMID:
10467133
[PubMed - indexed for MEDLINE]
Free Article
16.

Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells.

Secondo A, Sirabella R, Formisano L, D'Alessio A, Castaldo P, Amoroso S, Ingleton P, Di Renzo G, Annunziato L.

J Neurochem. 2003 Mar;84(6):1367-77.

PMID:
12614337
[PubMed - indexed for MEDLINE]
17.

Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.

Pene F, Claessens YE, Muller O, ViguiƩ F, Mayeux P, Dreyfus F, Lacombe C, Bouscary D.

Oncogene. 2002 Sep 26;21(43):6587-97.

PMID:
12242656
[PubMed - indexed for MEDLINE]
Free Article
19.

The Src-family tyrosine kinase inhibitor PP1 interferes with the activation of ribosomal protein S6 kinases.

Shah OJ, Kimball SR, Jefferson LS.

Biochem J. 2002 Aug 15;366(Pt 1):57-62.

PMID:
12014987
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs).

Feldman ME, Shokat KM.

Curr Top Microbiol Immunol. 2010;347:241-62. doi: 10.1007/82_2010_64. Review.

PMID:
20549474
[PubMed - indexed for MEDLINE]

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