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Results: 1 to 20 of 151

1.

p53 is regulated by the lysine demethylase LSD1.

Huang J, Sengupta R, Espejo AB, Lee MG, Dorsey JA, Richter M, Opravil S, Shiekhattar R, Bedford MT, Jenuwein T, Berger SL.

Nature. 2007 Sep 6;449(7158):105-8.

PMID:
17805299
[PubMed - indexed for MEDLINE]
2.

Repression of p53 activity by Smyd2-mediated methylation.

Huang J, Perez-Burgos L, Placek BJ, Sengupta R, Richter M, Dorsey JA, Kubicek S, Opravil S, Jenuwein T, Berger SL.

Nature. 2006 Nov 30;444(7119):629-32. Epub 2006 Nov 15.

PMID:
17108971
[PubMed - indexed for MEDLINE]
3.

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription.

Metzger E, Wissmann M, Yin N, Müller JM, Schneider R, Peters AH, Günther T, Buettner R, Schüle R.

Nature. 2005 Sep 15;437(7057):436-9. Epub 2005 Aug 3.

PMID:
16079795
[PubMed - indexed for MEDLINE]
4.

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y.

Cell. 2007 Mar 23;128(6):1077-88. Epub 2007 Feb 22.

PMID:
17320160
[PubMed - indexed for MEDLINE]
Free Article
5.

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.

Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y.

Nature. 2007 Aug 9;448(7154):718-22.

PMID:
17687328
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling.

Kachirskaia I, Shi X, Yamaguchi H, Tanoue K, Wen H, Wang EW, Appella E, Gozani O.

J Biol Chem. 2008 Dec 12;283(50):34660-6. doi: 10.1074/jbc.M806020200. Epub 2008 Oct 7.

PMID:
18840612
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

LSD1 demethylates histone and non-histone proteins.

Nicholson TB, Chen T.

Epigenetics. 2009 Apr 1;4(3):129-32. Epub 2009 Apr 14.

PMID:
19395867
[PubMed - indexed for MEDLINE]
Free Article
8.

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.

Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y.

Cell. 2004 Dec 29;119(7):941-53.

PMID:
15620353
[PubMed - indexed for MEDLINE]
Free Article
9.

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

Wissmann M, Yin N, Müller JM, Greschik H, Fodor BD, Jenuwein T, Vogler C, Schneider R, Günther T, Buettner R, Metzger E, Schüle R.

Nat Cell Biol. 2007 Mar;9(3):347-53. Epub 2007 Feb 4.

PMID:
17277772
[PubMed - indexed for MEDLINE]
10.

Visualizing the histone code on LSD1.

Gamble MJ, Kraus WL.

Cell. 2007 Feb 9;128(3):433-4.

PMID:
17289562
[PubMed - indexed for MEDLINE]
Free Article
11.

The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent manners.

Scoumanne A, Chen X.

J Biol Chem. 2007 May 25;282(21):15471-5. Epub 2007 Apr 4.

PMID:
17409384
[PubMed - indexed for MEDLINE]
Free Article
12.

Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.

Cho HS, Suzuki T, Dohmae N, Hayami S, Unoki M, Yoshimatsu M, Toyokawa G, Takawa M, Chen T, Kurash JK, Field HI, Ponder BA, Nakamura Y, Hamamoto R.

Cancer Res. 2011 Feb 1;71(3):655-60. doi: 10.1158/0008-5472.CAN-10-2446. Epub 2010 Nov 29.

PMID:
21115810
[PubMed - indexed for MEDLINE]
Free Article
13.

Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process.

Forneris F, Binda C, Vanoni MA, Mattevi A, Battaglioli E.

FEBS Lett. 2005 Apr 11;579(10):2203-7.

PMID:
15811342
[PubMed - indexed for MEDLINE]
Free Article
14.

Methylation-mediated regulation of E2F1 in DNA damage-induced cell death.

Xie Q, Bai Y, Wu J, Sun Y, Wang Y, Zhang Y, Mei P, Yuan Z.

J Recept Signal Transduct Res. 2011 Apr;31(2):139-46. doi: 10.3109/10799893.2011.552914. Epub 2011 Feb 15.

PMID:
21320024
[PubMed - indexed for MEDLINE]
15.

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M, Shi Y.

Cell. 2006 May 5;125(3):467-81. Epub 2006 Apr 6.

PMID:
16603238
[PubMed - indexed for MEDLINE]
Free Article
16.

Regulation of LSD1 histone demethylase activity by its associated factors.

Shi YJ, Matson C, Lan F, Iwase S, Baba T, Shi Y.

Mol Cell. 2005 Sep 16;19(6):857-64.

PMID:
16140033
[PubMed - indexed for MEDLINE]
Free Article
17.

p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo.

Tsai WW, Nguyen TT, Shi Y, Barton MC.

Mol Cell Biol. 2008 Sep;28(17):5139-46. doi: 10.1128/MCB.00287-08. Epub 2008 Jun 23.

PMID:
18573881
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase.

Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H.

Mol Cell. 2006 Aug 4;23(3):377-87.

PMID:
16885027
[PubMed - indexed for MEDLINE]
Free Article
19.

Protein methylation: a new mechanism of p53 tumor suppressor regulation.

Scoumanne A, Chen X.

Histol Histopathol. 2008 Sep;23(9):1143-9. Review.

PMID:
18581285
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The MBT repeats of L3MBTL1 link SET8-mediated p53 methylation at lysine 382 to target gene repression.

West LE, Roy S, Lachmi-Weiner K, Hayashi R, Shi X, Appella E, Kutateladze TG, Gozani O.

J Biol Chem. 2010 Nov 26;285(48):37725-32. doi: 10.1074/jbc.M110.139527. Epub 2010 Sep 24.

PMID:
20870725
[PubMed - indexed for MEDLINE]
Free PMC Article

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