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Items: 1 to 20 of 88

1.

Roles of secreted frizzled-related proteins in cancer.

Shi Y, He B, You L, Jablons DM.

Acta Pharmacol Sin. 2007 Sep;28(9):1499-504. Review.

2.

Secreted frizzled related proteins: Implications in cancers.

Surana R, Sikka S, Cai W, Shin EM, Warrier SR, Tan HJ, Arfuso F, Fox SA, Dharmarajan AM, Kumar AP.

Biochim Biophys Acta. 2014 Jan;1845(1):53-65. doi: 10.1016/j.bbcan.2013.11.004. Epub 2013 Dec 5. Review.

PMID:
24316024
3.

Secreted WNT antagonists as tumor suppressors: pro and con.

Rubin JS, Barshishat-Kupper M, Feroze-Merzoug F, Xi ZF.

Front Biosci. 2006 Sep 1;11:2093-105. Review.

PMID:
16720296
4.

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.

Bovolenta P, Esteve P, Ruiz JM, Cisneros E, Lopez-Rios J.

J Cell Sci. 2008 Mar 15;121(Pt 6):737-46. doi: 10.1242/jcs.026096. Review.

5.

Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer.

Aguilera O, Fraga MF, Ballestar E, Paz MF, Herranz M, Espada J, García JM, Muñoz A, Esteller M, González-Sancho JM.

Oncogene. 2006 Jul 6;25(29):4116-21. Epub 2006 Feb 20.

PMID:
16491118
6.

Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin.

Lavergne E, Hendaoui I, Coulouarn C, Ribault C, Leseur J, Eliat PA, Mebarki S, Corlu A, Clément B, Musso O.

Oncogene. 2011 Jan 27;30(4):423-33. doi: 10.1038/onc.2010.432. Epub 2010 Sep 20.

7.

Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells.

He B, Lee AY, Dadfarmay S, You L, Xu Z, Reguart N, Mazieres J, Mikami I, McCormick F, Jablons DM.

Cancer Res. 2005 Feb 1;65(3):743-8.

8.

Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway.

Urakami S, Shiina H, Enokida H, Kawakami T, Tokizane T, Ogishima T, Tanaka Y, Li LC, Ribeiro-Filho LA, Terashima M, Kikuno N, Adachi H, Yoneda T, Kishi H, Shigeno K, Konety BR, Igawa M, Dahiya R.

Clin Cancer Res. 2006 Jan 15;12(2):383-91.

10.

Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range.

Mii Y, Taira M.

Development. 2009 Dec;136(24):4083-8. doi: 10.1242/dev.032524. Epub 2009 Nov 11.

11.

Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma.

Kaur P, Mani S, Cros MP, Scoazec JY, Chemin I, Hainaut P, Herceg Z.

Tumour Biol. 2012 Apr;33(2):325-36. doi: 10.1007/s13277-012-0331-5. Epub 2012 Feb 15.

PMID:
22351518
12.

SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway.

Chung MT, Lai HC, Sytwu HK, Yan MD, Shih YL, Chang CC, Yu MH, Liu HS, Chu DW, Lin YW.

Gynecol Oncol. 2009 Mar;112(3):646-53. doi: 10.1016/j.ygyno.2008.10.026. Epub 2008 Dec 18.

PMID:
19095296
13.

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.

Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, Pretlow TP, Yang B, Akiyama Y, Van Engeland M, Toyota M, Tokino T, Hinoda Y, Imai K, Herman JG, Baylin SB.

Nat Genet. 2004 Apr;36(4):417-22. Epub 2004 Mar 14.

PMID:
15034581
14.

Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3.

Galli LM, Barnes T, Cheng T, Acosta L, Anglade A, Willert K, Nusse R, Burrus LW.

Dev Dyn. 2006 Mar;235(3):681-90.

15.

Secreted Wnt "inhibitors" are not just inhibitors: regulation of extracellular Wnt by secreted Frizzled-related proteins.

Mii Y, Taira M.

Dev Growth Differ. 2011 Oct;53(8):911-23. doi: 10.1111/j.1440-169X.2011.01299.x. Epub 2011 Oct 14. Review.

PMID:
21995331
16.

The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate.

Lopez-Rios J, Esteve P, Ruiz JM, Bovolenta P.

Neural Dev. 2008 Aug 20;3:19. doi: 10.1186/1749-8104-3-19.

17.

Characterization of sFRP2-like in amphioxus: insights into the evolutionary conservation of Wnt antagonizing function.

Kong W, Yang Y, Zhang T, Shi DL, Zhang Y.

Evol Dev. 2012 Mar-Apr;14(2):168-77. doi: 10.1111/j.1525-142X.2012.00533.x.

PMID:
23017025
18.

The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma.

Kongkham PN, Northcott PA, Croul SE, Smith CA, Taylor MD, Rutka JT.

Oncogene. 2010 May 20;29(20):3017-24. doi: 10.1038/onc.2010.32. Epub 2010 Mar 8.

PMID:
20208569
19.

Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma.

Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM.

Oncogene. 2004 Aug 26;23(39):6672-6.

PMID:
15221014
20.

Wnt/Frizzled signaling in hepatocellular carcinoma.

Lee HC, Kim M, Wands JR.

Front Biosci. 2006 May 1;11:1901-15. Review.

PMID:
16368566
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