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Results: 1 to 20 of 314

1.

Moving toward a system genetics view of disease.

Sieberts SK, Schadt EE.

Mamm Genome. 2007 Jul;18(6-7):389-401. Epub 2007 Jul 26. Review.

PMID:
17653589
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Novel integrative genomics strategies to identify genes for complex traits.

Schadt EE.

Anim Genet. 2006 Aug;37 Suppl 1:18-23.

PMID:
16886998
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A systems biology approach to drug discovery.

Zhu J, Zhang B, Schadt EE.

Adv Genet. 2008;60:603-35. doi: 10.1016/S0065-2660(07)00421-X. Review.

PMID:
18358334
[PubMed - indexed for MEDLINE]
4.

Using genetic markers to orient the edges in quantitative trait networks: the NEO software.

Aten JE, Fuller TF, Lusis AJ, Horvath S.

BMC Syst Biol. 2008 Apr 15;2:34. doi: 10.1186/1752-0509-2-34.

PMID:
18412962
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations.

Zhu J, Wiener MC, Zhang C, Fridman A, Minch E, Lum PY, Sachs JR, Schadt EE.

PLoS Comput Biol. 2007 Apr 13;3(4):e69. Epub 2007 Feb 27.

PMID:
17432931
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mapping the genetic architecture of gene expression in human liver.

Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R.

PLoS Biol. 2008 May 6;6(5):e107. doi: 10.1371/journal.pbio.0060107.

PMID:
18462017
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Gene expression network reconstruction by convex feature selection when incorporating genetic perturbations.

Logsdon BA, Mezey J.

PLoS Comput Biol. 2010 Dec 2;6(12):e1001014. doi: 10.1371/journal.pcbi.1001014.

PMID:
21152011
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice.

Drake TA, Schadt EE, Lusis AJ.

Mamm Genome. 2006 Jun;17(6):466-79. Epub 2006 Jun 12. Review.

PMID:
16783628
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Towards a comprehensive picture of the genetic landscape of complex traits.

Wang Z, Wang Y, Wang N, Wang J, Wang Z, Vallejos CE, Wu R.

Brief Bioinform. 2014 Jan;15(1):30-42. doi: 10.1093/bib/bbs049. Epub 2012 Aug 27.

PMID:
22930650
[PubMed - indexed for MEDLINE]
10.

Genetic variability of transcript abundance in pig peri-mortem skeletal muscle: eQTL localized genes involved in stress response, cell death, muscle disorders and metabolism.

Liaubet L, Lobjois V, Faraut T, Tircazes A, Benne F, Iannuccelli N, Pires J, Glénisson J, Robic A, Le Roy P, Sancristobal M, Cherel P.

BMC Genomics. 2011 Nov 4;12:548. doi: 10.1186/1471-2164-12-548.

PMID:
22053791
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genes and pathways contributing to obesity: a systems biology view.

Drake TA.

Prog Mol Biol Transl Sci. 2010;94:9-38. doi: 10.1016/S1877-1173(10)94002-7. Review.

PMID:
21036321
[PubMed - indexed for MEDLINE]
12.

An integrated approach to infer causal associations among gene expression, genotype variation, and disease.

Lee E, Cho S, Kim K, Park T.

Genomics. 2009 Oct;94(4):269-77. doi: 10.1016/j.ygeno.2009.06.002. Epub 2009 Jun 18.

PMID:
19540336
[PubMed - indexed for MEDLINE]
Free Article
13.

Statistical power of expression quantitative trait loci for mapping of complex trait loci in natural populations.

Schliekelman P.

Genetics. 2008 Apr;178(4):2201-16. doi: 10.1534/genetics.107.076687. Epub 2008 Feb 3.

PMID:
18245851
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

Systems genetics approaches to understand complex traits.

Civelek M, Lusis AJ.

Nat Rev Genet. 2014 Jan;15(1):34-48. doi: 10.1038/nrg3575. Epub 2013 Dec 3. Review.

PMID:
24296534
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Detection and interpretation of expression quantitative trait loci (eQTL).

Michaelson JJ, Loguercio S, Beyer A.

Methods. 2009 Jul;48(3):265-76. doi: 10.1016/j.ymeth.2009.03.004. Epub 2009 Mar 18.

PMID:
19303049
[PubMed - indexed for MEDLINE]
17.

Uncovering the genetic landscape for multiple sleep-wake traits.

Winrow CJ, Williams DL, Kasarskis A, Millstein J, Laposky AD, Yang HS, Mrazek K, Zhou L, Owens JR, Radzicki D, Preuss F, Schadt EE, Shimomura K, Vitaterna MH, Zhang C, Koblan KS, Renger JJ, Turek FW.

PLoS One. 2009;4(4):e5161. doi: 10.1371/journal.pone.0005161. Epub 2009 Apr 10.

PMID:
19360106
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Systems and Synthetic biology: tackling genetic networks and complex diseases.

Cuccato G, Della Gatta G, di Bernardo D.

Heredity (Edinb). 2009 Jun;102(6):527-32. doi: 10.1038/hdy.2009.18. Epub 2009 Mar 4. Review.

PMID:
19259117
[PubMed - indexed for MEDLINE]
Free Article
19.

Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake.

Millstein J, Winrow CJ, Kasarskis A, Owens JR, Zhou L, Summa KC, Fitzpatrick K, Zhang B, Vitaterna MH, Schadt EE, Renger JJ, Turek FW.

Sleep. 2011 Nov 1;34(11):1469-77. doi: 10.5665/sleep.1378.

PMID:
22043117
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Allele-specific behavior of molecular networks: understanding small-molecule drug response in yeast.

Zhang F, Gao B, Xu L, Li C, Hao D, Zhang S, Zhou M, Su F, Chen X, Zhi H, Li X.

PLoS One. 2013;8(1):e53581. doi: 10.1371/journal.pone.0053581. Epub 2013 Jan 4.

PMID:
23308257
[PubMed - indexed for MEDLINE]
Free PMC Article
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