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Items: 1 to 20 of 135


Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia.

Shivakumar P, Sabla G, Mohanty S, McNeal M, Ward R, Stringer K, Caldwell C, Chougnet C, Bezerra JA.

Gastroenterology. 2007 Jul;133(1):268-77. Epub 2007 Apr 20.


CD8+ T lymphocyte response against extrahepatic biliary epithelium is activated by epitopes within NSP4 in experimental biliary atresia.

Zheng S, Zhang H, Zhang X, Peng F, Chen X, Yang J, Brigstock D, Feng J.

Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15;307(2):G233-40. doi: 10.1152/ajpgi.00099.2014. Epub 2014 May 29.


Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia.

Lages CS, Simmons J, Chougnet CA, Miethke AG.

Hepatology. 2012 Jul;56(1):219-27. doi: 10.1002/hep.25662. Epub 2012 Jun 6.


Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia.

Shivakumar P, Campbell KM, Sabla GE, Miethke A, Tiao G, McNeal MM, Ward RL, Bezerra JA.

J Clin Invest. 2004 Aug;114(3):322-9.


Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia.

Shivakumar P, Sabla GE, Whitington P, Chougnet CA, Bezerra JA.

J Clin Invest. 2009 Aug;119(8):2281-90.


Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia.

Mack CL, Tucker RM, Lu BR, Sokol RJ, Fontenot AP, Ueno Y, Gill RG.

Hepatology. 2006 Nov;44(5):1231-9.


Perforin and granzymes work in synergy to mediate cholangiocyte injury in experimental biliary atresia.

Shivakumar P, Mourya R, Bezerra JA.

J Hepatol. 2014 Feb;60(2):370-6. doi: 10.1016/j.jhep.2013.09.021. Epub 2013 Oct 2.


Role of myeloid differentiation factor 88 in Rhesus rotavirus-induced biliary atresia.

Walther AE, Mohanty SK, Donnelly B, Coots A, McNeal M, Tiao GM.

J Surg Res. 2013 Sep;184(1):322-9. doi: 10.1016/j.jss.2013.05.032. Epub 2013 Jun 1.


Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia.

Miethke AG, Saxena V, Shivakumar P, Sabla GE, Simmons J, Chougnet CA.

J Hepatol. 2010 May;52(5):718-26. doi: 10.1016/j.jhep.2009.12.027. Epub 2010 Mar 5.


Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia.

Saxena V, Shivakumar P, Sabla G, Mourya R, Chougnet C, Bezerra JA.

Sci Transl Med. 2011 Sep 28;3(102):102ra94. doi: 10.1126/scitranslmed.3002069.


Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia.

Tucker RM, Feldman AG, Fenner EK, Mack CL.

J Hepatol. 2013 Oct;59(4):790-6. doi: 10.1016/j.jhep.2013.05.010. Epub 2013 May 14.


Cholangiocytes as immune modulators in rotavirus-induced murine biliary atresia.

Barnes BH, Tucker RM, Wehrmann F, Mack DG, Ueno Y, Mack CL.

Liver Int. 2009 Sep;29(8):1253-61. doi: 10.1111/j.1478-3231.2008.01921.x. Epub 2008 Nov 15.


Temporal-spatial activation of apoptosis and epithelial injury in murine experimental biliary atresia.

Erickson N, Mohanty SK, Shivakumar P, Sabla G, Chakraborty R, Bezerra JA.

Hepatology. 2008 May;47(5):1567-77. doi: 10.1002/hep.22229.


Low doses of CMV induce autoimmune-mediated and inflammatory responses in bile duct epithelia of regulatory T cell-depleted neonatal mice.

Wen J, Xiao Y, Wang J, Pan W, Zhou Y, Zhang X, Guan W, Chen Y, Zhou K, Wang Y, Shi B, Zhou X, Yuan Z, Cai W.

Lab Invest. 2015 Feb;95(2):180-92. doi: 10.1038/labinvest.2014.148. Epub 2014 Dec 22.


Oligoclonal expansions of CD4+ and CD8+ T-cells in the target organ of patients with biliary atresia.

Mack CL, Falta MT, Sullivan AK, Karrer F, Sokol RJ, Freed BM, Fontenot AP.

Gastroenterology. 2007 Jul;133(1):278-87. Epub 2007 Apr 20.


Rotavirus particles in the extrahepatic bile duct in experimental biliary atresia.

Oetzmann von Sochaczewski C, Pintelon I, Brouns I, Dreier A, Klemann C, Timmermans JP, Petersen C, Kuebler JF.

J Pediatr Surg. 2014 Apr;49(4):520-4. doi: 10.1016/j.jpedsurg.2013.09.064. Epub 2013 Oct 19.


Extrahepatic cholangiocyte cilia are abnormal in biliary atresia.

Karjoo S, Hand NJ, Loarca L, Russo PA, Friedman JR, Wells RG.

J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):96-101. doi: 10.1097/MPG.0b013e318296e525.


Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype.

Li J, Bessho K, Shivakumar P, Mourya R, Mohanty SK, Dos Santos JL, Miura IK, Porta G, Bezerra JA.

J Clin Invest. 2011 Nov;121(11):4244-56. doi: 10.1172/JCI57728. Epub 2011 Oct 17.


Combinatory effects of hepatic CD8+ and NK lymphocytes in bile duct injury from biliary atresia.

Guo C, Zhu J, Pu CL, Deng YH, Zhang MM.

Pediatr Res. 2012 Jun;71(6):638-44. doi: 10.1038/pr.2012.17. Epub 2012 Feb 14.

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