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Results: 1 to 20 of 101

1.

AML1-ETO meets JAK2: clinical evidence for the two hit model of leukemogenesis from a myeloproliferative syndrome progressing to acute myeloid leukemia.

Schneider F, Bohlander SK, Schneider S, Papadaki C, Kakadyia P, Dufour A, Vempati S, Unterhalt M, Feuring-Buske M, Buske C, Braess J, Wandt H, Hiddemann W, Spiekermann K.

Leukemia. 2007 Oct;21(10):2199-201. Epub 2007 Jul 12. No abstract available.

PMID:
17625612
[PubMed - indexed for MEDLINE]
2.

The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia.

Vangala RK, Heiss-Neumann MS, Rangatia JS, Singh SM, Schoch C, Tenen DG, Hiddemann W, Behre G.

Blood. 2003 Jan 1;101(1):270-7. Epub 2002 Aug 29.

PMID:
12393465
[PubMed - indexed for MEDLINE]
Free Article
3.

Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.

Fazi F, Racanicchi S, Zardo G, Starnes LM, Mancini M, Travaglini L, Diverio D, Ammatuna E, Cimino G, Lo-Coco F, Grignani F, Nervi C.

Cancer Cell. 2007 Nov;12(5):457-66.

PMID:
17996649
[PubMed - indexed for MEDLINE]
Free Article
4.

Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia.

Miyamoto T, Nagafuji K, Akashi K, Harada M, Kyo T, Akashi T, Takenaka K, Mizuno S, Gondo H, Okamura T, Dohy H, Niho Y.

Blood. 1996 Jun 1;87(11):4789-96.

PMID:
8639850
[PubMed - indexed for MEDLINE]
Free Article
5.

c-Jun N-terminal kinase mediates AML1-ETO protein-induced connexin-43 expression.

Gao FH, Wang Q, Wu YL, Li X, Zhao KW, Chen GQ.

Biochem Biophys Res Commun. 2007 May 4;356(2):505-11. Epub 2007 Mar 8.

PMID:
17367753
[PubMed - indexed for MEDLINE]
6.

AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.

Licht JD.

Oncogene. 2001 Sep 10;20(40):5660-79. Review. No abstract available.

PMID:
11607817
[PubMed - indexed for MEDLINE]
Free Article
7.

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations.

Yuan Y, Zhou L, Miyamoto T, Iwasaki H, Harakawa N, Hetherington CJ, Burel SA, Lagasse E, Weissman IL, Akashi K, Zhang DE.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10398-403.

PMID:
11526243
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Identification of two transcripts of AML1/ETO-fused gene in t(8;21) leukemic cells and expression of wild-type ETO gene in hematopoietic cells.

Era T, Asou N, Kunisada T, Yamasaki H, Asou H, Kamada N, Nishikawa S, Yamaguchi K, Takatsuki K.

Genes Chromosomes Cancer. 1995 May;13(1):25-33.

PMID:
7541640
[PubMed - indexed for MEDLINE]
9.

New mechanisms of AML1 gene alteration in hematological malignancies.

Roumier C, Fenaux P, Lafage M, Imbert M, Eclache V, Preudhomme C.

Leukemia. 2003 Jan;17(1):9-16. Review.

PMID:
12529654
[PubMed - indexed for MEDLINE]
10.

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia.

Higuchi M, O'Brien D, Kumaravelu P, Lenny N, Yeoh EJ, Downing JR.

Cancer Cell. 2002 Feb;1(1):63-74.

PMID:
12086889
[PubMed - indexed for MEDLINE]
11.

High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21.

Preudhomme C, Warot-Loze D, Roumier C, Grardel-Duflos N, Garand R, Lai JL, Dastugue N, Macintyre E, Denis C, Bauters F, Kerckaert JP, Cosson A, Fenaux P.

Blood. 2000 Oct 15;96(8):2862-9.

PMID:
11023523
[PubMed - indexed for MEDLINE]
Free Article
12.

[Effective and specific control of aml1/eto gene expression in acute myeloid leukemia cells by lentivecior-based RNA-interference].

Grinev VV, Posrednik DV, Heidenreich O.

Mol Biol (Mosk). 2011 Mar-Apr;45(2):335-45. Russian.

PMID:
21634121
[PubMed - indexed for MEDLINE]
13.

Aml1 gene rearrangements and mutations in radiation-associated acute myeloid leukemia and myelodysplastic syndromes.

Klymenko S, Trott K, Atkinson M, Bink K, Bebeshko V, Bazyka D, Dmytrenko I, Abramenko I, Bilous N, Misurin A, Zitzelsberger H, Rosemann M.

J Radiat Res. 2005 Jun;46(2):249-55.

PMID:
15988144
[PubMed - indexed for MEDLINE]
Free Article
14.

Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia of the M0 subtype.

Matsuno N, Osato M, Yamashita N, Yanagida M, Nanri T, Fukushima T, Motoji T, Kusumoto S, Towatari M, Suzuki R, Naoe T, Nishii K, Shigesada K, Ohno R, Mitsuya H, Ito Y, Asou N.

Leukemia. 2003 Dec;17(12):2492-9.

PMID:
14562119
[PubMed - indexed for MEDLINE]
15.

NHR4 domain mutations of ETO are probably very infrequent in AML1-ETO positive myeloid leukemia cells.

Hackanson B, Abdelkarim M, Jansen JH, L├╝bbert M.

Leukemia. 2010 Apr;24(4):860-1. doi: 10.1038/leu.2009.291. Epub 2010 Jan 21. No abstract available.

PMID:
20090777
[PubMed - indexed for MEDLINE]
16.

The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor.

McNeil S, Zeng C, Harrington KS, Hiebert S, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14882-7.

PMID:
10611307
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

Pabst T, Mueller BU, Harakawa N, Schoch C, Haferlach T, Behre G, Hiddemann W, Zhang DE, Tenen DG.

Nat Med. 2001 Apr;7(4):444-51.

PMID:
11283671
[PubMed - indexed for MEDLINE]
18.

[Mechanism of leukemogenesis induced by AML 1-MTG 8].

Kitabayashi I, Ohki M.

Tanpakushitsu Kakusan Koso. 2000 Jan;45(1):26-32. Review. Japanese. No abstract available.

PMID:
10643332
[PubMed - indexed for MEDLINE]
19.

Recurrence of acute myelogenous leukemia with the same AML1/ETO breakpoint as at diagnosis after complete remission lasting 15 years: analysis of stored bone marrow smears.

Tsukamoto N, Karasawa M, Tanaka Y, Yokohama A, Uchiumi H, Matsushima T, Murakami H, Nojima Y.

Int J Hematol. 2003 Nov;78(4):362-9.

PMID:
14686496
[PubMed - indexed for MEDLINE]
20.

Transcription of the AML1/ETO chimera is guided by the P2 promoter of the AML1 gene in the Kasumi-1 cell line.

Markova EN, Kantidze OL, Razin SV.

Gene. 2012 Dec 1;510(2):142-6. doi: 10.1016/j.gene.2012.09.028. Epub 2012 Sep 17.

PMID:
22995345
[PubMed - indexed for MEDLINE]

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