Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 392

1.

IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells.

Patterson J, Palombella VJ, Fritz C, Normant E.

Cancer Chemother Pharmacol. 2008 May;61(6):923-32. Epub 2007 Jul 12.

PMID:
17624530
[PubMed - indexed for MEDLINE]
2.

Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.

Manni S, Brancalion A, Tubi LQ, Colpo A, Pavan L, Cabrelle A, Ave E, Zaffino F, Di Maira G, Ruzzene M, Adami F, Zambello R, Pitari MR, Tassone P, Pinna LA, Gurrieri C, Semenzato G, Piazza F.

Clin Cancer Res. 2012 Apr 1;18(7):1888-900. doi: 10.1158/1078-0432.CCR-11-1789. Epub 2012 Feb 20.

PMID:
22351691
[PubMed - indexed for MEDLINE]
Free Article
3.

Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells.

Davenport EL, Moore HE, Dunlop AS, Sharp SY, Workman P, Morgan GJ, Davies FE.

Blood. 2007 Oct 1;110(7):2641-9. Epub 2007 May 24.

PMID:
17525289
[PubMed - indexed for MEDLINE]
Free Article
5.

The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor.

Thomas M, Yu Z, Dadgar N, Varambally S, Yu J, Chinnaiyan AM, Lieberman AP.

J Biol Chem. 2005 Jun 3;280(22):21264-71. Epub 2005 Mar 30.

PMID:
15799970
[PubMed - indexed for MEDLINE]
Free Article
6.

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.

Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ.

Genes Dev. 2002 Feb 15;16(4):452-66.

PMID:
11850408
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling.

van Huizen R, Martindale JL, Gorospe M, Holbrook NJ.

J Biol Chem. 2003 May 2;278(18):15558-64. Epub 2003 Feb 24.

PMID:
12601012
[PubMed - indexed for MEDLINE]
Free Article
8.

The PERK/eIF2 alpha signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells.

Lai WL, Wong NS.

Exp Cell Res. 2008 May 1;314(8):1667-82. doi: 10.1016/j.yexcr.2008.02.002. Epub 2008 Mar 14.

PMID:
18342855
[PubMed - indexed for MEDLINE]
9.

Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response.

Li B, Gao B, Ye L, Han X, Wang W, Kong L, Fang X, Zeng Y, Zheng H, Li S, Wu Z, Ye L.

Virus Res. 2007 Mar;124(1-2):44-9. Epub 2006 Nov 7.

PMID:
17092596
[PubMed - indexed for MEDLINE]
10.

BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth.

Yasui H, Hideshima T, Ikeda H, Jin J, Ocio EM, Kiziltepe T, Okawa Y, Vallet S, Podar K, Ishitsuka K, Richardson PG, Pargellis C, Moss N, Raje N, Anderson KC.

Br J Haematol. 2007 Feb;136(3):414-23. Epub 2006 Dec 14.

PMID:
17173546
[PubMed - indexed for MEDLINE]
11.

Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation.

Fionda C, Soriani A, Malgarini G, Iannitto ML, Santoni A, Cippitelli M.

J Immunol. 2009 Oct 1;183(7):4385-94. doi: 10.4049/jimmunol.0901797. Epub 2009 Sep 11.

PMID:
19748980
[PubMed - indexed for MEDLINE]
Free Article
12.

Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons.

Holtz WA, O'Malley KL.

J Biol Chem. 2003 May 23;278(21):19367-77. Epub 2003 Feb 21.

PMID:
12598533
[PubMed - indexed for MEDLINE]
Free Article
13.

Effect on tumor cells of blocking survival response to glucose deprivation.

Park HR, Tomida A, Sato S, Tsukumo Y, Yun J, Yamori T, Hayakawa Y, Tsuruo T, Shin-ya K.

J Natl Cancer Inst. 2004 Sep 1;96(17):1300-10.

PMID:
15339968
[PubMed - indexed for MEDLINE]
Free Article
14.

Untangling the unfolded protein response.

Davenport EL, Morgan GJ, Davies FE.

Cell Cycle. 2008 Apr 1;7(7):865-9. Epub 2008 Jan 9. Review.

PMID:
18414035
[PubMed - indexed for MEDLINE]
Free Article
15.

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response.

Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, Mori K.

Mol Cell Biol. 2000 Sep;20(18):6755-67.

PMID:
10958673
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death.

Chambers KT, Unverferth JA, Weber SM, Wek RC, Urano F, Corbett JA.

Diabetes. 2008 Jan;57(1):124-32. Epub 2007 Oct 10.

PMID:
17928398
[PubMed - indexed for MEDLINE]
Free Article
17.

Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.

Yokouchi M, Hiramatsu N, Hayakawa K, Kasai A, Takano Y, Yao J, Kitamura M.

Cell Death Differ. 2007 Aug;14(8):1467-74. Epub 2007 Apr 27.

PMID:
17464326
[PubMed - indexed for MEDLINE]
Free Article
18.

STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90alpha and beta in multiple myeloma cells, which critically contribute to tumor-cell survival.

Chatterjee M, Jain S, Stühmer T, Andrulis M, Ungethüm U, Kuban RJ, Lorentz H, Bommert K, Topp M, Krämer D, Müller-Hermelink HK, Einsele H, Greiner A, Bargou RC.

Blood. 2007 Jan 15;109(2):720-8. Epub 2006 Sep 26.

PMID:
17003370
[PubMed - indexed for MEDLINE]
Free Article
19.

The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells.

Gass JN, Jiang HY, Wek RC, Brewer JW.

Mol Immunol. 2008 Feb;45(4):1035-43. Epub 2007 Sep 5.

PMID:
17822768
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Analysis of expression of heat shock protein-90 (HSP90) and the effects of HSP90 inhibitor (17-AAG) in multiple myeloma.

Duus J, Bahar HI, Venkataraman G, Ozpuyan F, Izban KF, Al-Masri H, Maududi T, Toor A, Alkan S.

Leuk Lymphoma. 2006 Jul;47(7):1369-78.

PMID:
16923571
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk