Items per page
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 97


Choline deficiency increases lymphocyte apoptosis and DNA damage in humans.

da Costa KA, Niculescu MD, Craciunescu CN, Fischer LM, Zeisel SH.

Am J Clin Nutr. 2006 Jul;84(1):88-94.


Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans.

Kohlmeier M, da Costa KA, Fischer LM, Zeisel SH.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16025-30. Epub 2005 Oct 18.


Common genetic polymorphisms affect the human requirement for the nutrient choline.

da Costa KA, Kozyreva OG, Song J, Galanko JA, Fischer LM, Zeisel SH.

FASEB J. 2006 Jul;20(9):1336-44.


Dietary choline requirements of women: effects of estrogen and genetic variation.

Fischer LM, da Costa KA, Kwock L, Galanko J, Zeisel SH.

Am J Clin Nutr. 2010 Nov;92(5):1113-9. doi: 10.3945/ajcn.2010.30064. Epub 2010 Sep 22.


Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline.

Sha W, da Costa KA, Fischer LM, Milburn MV, Lawton KA, Berger A, Jia W, Zeisel SH.

FASEB J. 2010 Aug;24(8):2962-75. doi: 10.1096/fj.09-154054. Epub 2010 Apr 6.


Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort.

Silver MJ, Corbin KD, Hellenthal G, da Costa KA, Dominguez-Salas P, Moore SE, Owen J, Prentice AM, Hennig BJ, Zeisel SH.

FASEB J. 2015 Aug;29(8):3426-35. doi: 10.1096/fj.15-271056. Epub 2015 Apr 28.


Nutritional genomics: defining the dietary requirement and effects of choline.

Zeisel SH.

J Nutr. 2011 Mar;141(3):531-4. doi: 10.3945/jn.110.130369. Epub 2011 Jan 26. Review.


Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma.

Fischer LM, da Costa KA, Galanko J, Sha W, Stephenson B, Vick J, Zeisel SH.

Am J Clin Nutr. 2010 Aug;92(2):336-46. doi: 10.3945/ajcn.2010.29459. Epub 2010 Jun 9.


Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans.

da Costa KA, Sanders LM, Fischer LM, Zeisel SH.

Am J Clin Nutr. 2011 May;93(5):968-74. doi: 10.3945/ajcn.110.011064. Epub 2011 Mar 16.


Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency.

Spencer MD, Hamp TJ, Reid RW, Fischer LM, Zeisel SH, Fodor AA.

Gastroenterology. 2011 Mar;140(3):976-86. doi: 10.1053/j.gastro.2010.11.049. Epub 2010 Dec 1.


Sex and menopausal status influence human dietary requirements for the nutrient choline.

Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu TS, Stabler SP, Allen RH, Zeisel SH.

Am J Clin Nutr. 2007 May;85(5):1275-85.


Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury.

Pogribny IP, Kutanzi K, Melnyk S, de Conti A, Tryndyak V, Montgomery B, Pogribna M, Muskhelishvili L, Latendresse JR, James SJ, Beland FA, Rusyn I.

FASEB J. 2013 Jun;27(6):2233-43. doi: 10.1096/fj.12-227116. Epub 2013 Feb 25.


Choline deficiency-induced liver damage is reversible in Pemt(-/-) mice.

Waite KA, Cabilio NR, Vance DE.

J Nutr. 2002 Jan;132(1):68-71.


Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction.

Resseguie ME, da Costa KA, Galanko JA, Patel M, Davis IJ, Zeisel SH.

J Biol Chem. 2011 Jan 14;286(2):1649-58. doi: 10.1074/jbc.M110.106922. Epub 2010 Nov 8.


Choline supplementation protects against liver damage by normalizing cholesterol metabolism in Pemt/Ldlr knockout mice fed a high-fat diet.

Al Rajabi A, Castro GS, da Silva RP, Nelson RC, Thiesen A, Vannucchi H, Vine DF, Proctor SD, Field CJ, Curtis JM, Jacobs RL.

J Nutr. 2014 Mar;144(3):252-7. doi: 10.3945/jn.113.185389. Epub 2013 Dec 24.

Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk