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Items: 1 to 20 of 95

1.

Convergent Functional Genomics of bipolar disorder: from animal model pharmacogenomics to human genetics and biomarkers.

Le-Niculescu H, McFarland MJ, Mamidipalli S, Ogden CA, Kuczenski R, Kurian SM, Salomon DR, Tsuang MT, Nurnberger JI Jr, Niculescu AB.

Neurosci Biobehav Rev. 2007;31(6):897-903. Epub 2007 Jun 3. Review.

2.

Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders.

Bertsch B, Ogden CA, Sidhu K, Le-Niculescu H, Kuczenski R, Niculescu AB.

Methods. 2005 Nov;37(3):274-9.

PMID:
16308156
3.

Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms.

Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, McMahon FJ, Schork NJ, Nurnberger JI Jr, Niculescu AB 3rd.

Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):155-81. doi: 10.1002/ajmg.b.30887.

PMID:
19025758
4.

Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach.

Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer MA, Lohr JB, Kuczenski R, Niculescu AB.

Mol Psychiatry. 2004 Nov;9(11):1007-29.

PMID:
15314610
5.

Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms.

Le-Niculescu H, Balaraman Y, Patel SD, Ayalew M, Gupta J, Kuczenski R, Shekhar A, Schork N, Geyer MA, Niculescu AB.

Transl Psychiatry. 2011 May 24;1:e9. doi: 10.1038/tp.2011.9.

6.

Genetic risk prediction and neurobiological understanding of alcoholism.

Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Wodarz N, Müller-Myhsok B, Dahmen N; GESGA Consortium, Nöthen M, Sherva R, Farrer L, Smith AH, Kranzler HR, Rietschel M, Gelernter J, Niculescu AB.

Transl Psychiatry. 2014 May 20;4:e391. doi: 10.1038/tp.2014.29. Erratum in: Transl Psychiatry. 2014;4:e456. Kiefe, F [corrected to Kiefer, F].

7.

Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics.

Patel SD, Le-Niculescu H, Koller DL, Green SD, Lahiri DK, McMahon FJ, Nurnberger JI Jr, Niculescu AB 3rd.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):850-77. doi: 10.1002/ajmg.b.31087.

PMID:
20468069
8.

Discovery and validation of blood biomarkers for suicidality.

Le-Niculescu H, Levey DF, Ayalew M, Palmer L, Gavrin LM, Jain N, Winiger E, Bhosrekar S, Shankar G, Radel M, Bellanger E, Duckworth H, Olesek K, Vergo J, Schweitzer R, Yard M, Ballew A, Shekhar A, Sandusky GE, Schork NJ, Kurian SM, Salomon DR, Niculescu AB 3rd.

Mol Psychiatry. 2013 Dec;18(12):1249-64. doi: 10.1038/mp.2013.95. Epub 2013 Aug 20.

9.

Identifying blood biomarkers for mood disorders using convergent functional genomics.

Le-Niculescu H, Kurian SM, Yehyawi N, Dike C, Patel SD, Edenberg HJ, Tsuang MT, Salomon DR, Nurnberger JI Jr, Niculescu AB.

Mol Psychiatry. 2009 Feb;14(2):156-74. doi: 10.1038/mp.2008.11. Epub 2008 Feb 26. Erratum in: Mol Psychiatry. 2009 Dec;14(12):1143.

PMID:
18301394
10.

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.

Ayalew M, Le-Niculescu H, Levey DF, Jain N, Changala B, Patel SD, Winiger E, Breier A, Shekhar A, Amdur R, Koller D, Nurnberger JI, Corvin A, Geyer M, Tsuang MT, Salomon D, Schork NJ, Fanous AH, O'Donovan MC, Niculescu AB.

Mol Psychiatry. 2012 Sep;17(9):887-905. doi: 10.1038/mp.2012.37. Epub 2012 May 15.

11.

Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness).

Le-Niculescu H, Patel SD, Niculescu AB.

Curr Opin Pharmacol. 2010 Oct;10(5):594-600. doi: 10.1016/j.coph.2010.08.008. Review.

PMID:
20817606
12.

Towards understanding the schizophrenia code: an expanded convergent functional genomics approach.

Le-Niculescu H, Balaraman Y, Patel S, Tan J, Sidhu K, Jerome RE, Edenberg HJ, Kuczenski R, Geyer MA, Nurnberger JI Jr, Faraone SV, Tsuang MT, Niculescu AB.

Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5;144B(2):129-58.

PMID:
17266109
13.

Schizophrenia: from genetics to biology to predictive medicine.

Niculescu AB 3rd.

J Clin Psychiatry. 2014;75 Suppl 2:4-7. doi: 10.4088/JCP.13065su1.01. Review.

14.

Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism.

Le-Niculescu H, McFarland MJ, Ogden CA, Balaraman Y, Patel S, Tan J, Rodd ZA, Paulus M, Geyer MA, Edenberg HJ, Glatt SJ, Faraone SV, Nurnberger JI, Kuczenski R, Tsuang MT, Niculescu AB.

Am J Med Genet B Neuropsychiatr Genet. 2008 Mar 5;147B(2):134-66. doi: 10.1002/ajmg.b.30707.

PMID:
18247375
15.

Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism.

Le-Niculescu H, Case NJ, Hulvershorn L, Patel SD, Bowker D, Gupta J, Bell R, Edenberg HJ, Tsuang MT, Kuczenski R, Geyer MA, Rodd ZA, Niculescu AB.

Transl Psychiatry. 2011 Apr 26;1:e4. doi: 10.1038/tp.2011.1.

16.

Genetics of bipolar disorder.

Escamilla MA, Zavala JM.

Dialogues Clin Neurosci. 2008;10(2):141-52. Review.

17.

Convergent functional genomics: application to bipolar disorder.

Niculescu AB 3rd, Kelsoe JR.

Ann Med. 2001 May;33(4):263-71. Review.

PMID:
11405548
18.

Convergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms.

Niculescu AB, Le-Niculescu H.

Neuropsychopharmacology. 2010 Jan;35(1):355-6. doi: 10.1038/npp.2009.107. No abstract available.

19.

[Genetics of bipolar disorder].

Michelon L, Vallada H.

Rev Bras Psiquiatr. 2004 Oct;26 Suppl 3:12-6. Epub 2004 Dec 7. Portuguese.

20.

Identification of blood biomarkers for psychosis using convergent functional genomics.

Kurian SM, Le-Niculescu H, Patel SD, Bertram D, Davis J, Dike C, Yehyawi N, Lysaker P, Dustin J, Caligiuri M, Lohr J, Lahiri DK, Nurnberger JI Jr, Faraone SV, Geyer MA, Tsuang MT, Schork NJ, Salomon DR, Niculescu AB.

Mol Psychiatry. 2011 Jan;16(1):37-58. doi: 10.1038/mp.2009.117. Epub 2009 Nov 24.

PMID:
19935739
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