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Results: 1 to 20 of 135

1.

The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview.

Liu J.

Neurochem Res. 2008 Jan;33(1):194-203. Epub 2007 Jun 29. Review.

PMID:
17605107
[PubMed - indexed for MEDLINE]
2.

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites.

Liu J, Atamna H, Kuratsune H, Ames BN.

Ann N Y Acad Sci. 2002 Apr;959:133-66. Review.

PMID:
11976193
[PubMed - indexed for MEDLINE]
3.

Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.

Hagen TM, Moreau R, Suh JH, Visioli F.

Ann N Y Acad Sci. 2002 Apr;959:491-507. Review.

PMID:
11976222
[PubMed - indexed for MEDLINE]
4.

Biologic activity of mitochondrial metabolites on aging and age-related hearing loss.

Seidman MD, Khan MJ, Bai U, Shirwany N, Quirk WS.

Am J Otol. 2000 Mar;21(2):161-7.

PMID:
10733178
[PubMed - indexed for MEDLINE]
5.

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.

Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2356-61. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184-5.

PMID:
11854529
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid.

Shen W, Liu K, Tian C, Yang L, Li X, Ren J, Packer L, Head E, Sharman E, Liu J.

J Cell Biochem. 2008 Jul 1;104(4):1232-43. doi: 10.1002/jcb.21701.

PMID:
18260126
[PubMed - indexed for MEDLINE]
7.

Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

Zhang H, Jia H, Liu J, Ao N, Yan B, Shen W, Wang X, Li X, Luo C, Liu J.

J Cell Mol Med. 2010 Jan;14(1-2):215-25. doi: 10.1111/j.1582-4934.2008.00390.x.

PMID:
20414966
[PubMed - indexed for MEDLINE]
8.

Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats.

Hao J, Shen W, Tian C, Liu Z, Ren J, Luo C, Long J, Sharman E, Liu J.

J Cell Mol Med. 2009 Apr;13(4):701-11. doi: 10.1111/j.1582-4934.2008.00342.x. Epub 2008 Apr 10.

PMID:
18410524
[PubMed - indexed for MEDLINE]
9.

Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders?

Soczynska JK, Kennedy SH, Chow CS, Woldeyohannes HO, Konarski JZ, McIntyre RS.

Expert Opin Investig Drugs. 2008 Jun;17(6):827-43. doi: 10.1517/13543784.17.6.827 . Review.

PMID:
18491985
[PubMed - indexed for MEDLINE]
10.

R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes.

Shen W, Liu K, Tian C, Yang L, Li X, Ren J, Packer L, Cotman CW, Liu J.

Diabetologia. 2008 Jan;51(1):165-74. Epub 2007 Nov 17.

PMID:
18026715
[PubMed - indexed for MEDLINE]
11.
12.

Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.

Long J, Gao F, Tong L, Cotman CW, Ames BN, Liu J.

Neurochem Res. 2009 Apr;34(4):755-63. doi: 10.1007/s11064-008-9850-2. Epub 2008 Oct 10.

PMID:
18846423
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Oxidative stress on mitochondrial antioxidant defense system in the aging process: role of DL-alpha-lipoic acid and L-carnitine.

Savitha S, Tamilselvan J, Anusuyadevi M, Panneerselvam C.

Clin Chim Acta. 2005 May;355(1-2):173-80.

PMID:
15820492
[PubMed - indexed for MEDLINE]
14.

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.

Liu J, Killilea DW, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1876-81. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184.

PMID:
11854488
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mitochondrial membrane damage during aging process in rat heart: potential efficacy of L-carnitine and DL alpha lipoic acid.

Savitha S, Panneerselvam C.

Mech Ageing Dev. 2006 Apr;127(4):349-55. Epub 2006 Jan 20.

PMID:
16430943
[PubMed - indexed for MEDLINE]
16.

Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans.

Brown MK, Evans JL, Luo Y.

Pharmacol Biochem Behav. 2006 Nov;85(3):620-8. Epub 2006 Dec 5.

PMID:
17156833
[PubMed - indexed for MEDLINE]
17.

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.

Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G.

J Alzheimers Dis. 2007 Sep;12(2):195-206. Review.

PMID:
17917164
[PubMed - indexed for MEDLINE]
18.

High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinson's disease.

Jia H, Li X, Gao H, Feng Z, Li X, Zhao L, Jia X, Zhang H, Liu J.

J Neurosci Res. 2008 Jul;86(9):2083-90. doi: 10.1002/jnr.21650.

PMID:
18381761
[PubMed - indexed for MEDLINE]
19.

Cytochrome c oxidase rather than cytochrome c is a major determinant of mitochondrial respiratory capacity in skeletal muscle of aged rats: role of carnitine and lipoic acid.

Tamilselvan J, Sivarajan K, Anusuyadevi M, Panneerselvam C.

Rejuvenation Res. 2007 Sep;10(3):311-26.

PMID:
17555400
[PubMed - indexed for MEDLINE]
20.

Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging.

Savitha S, Sivarajan K, Haripriya D, Kokilavani V, Panneerselvam C.

Clin Nutr. 2005 Oct;24(5):794-800.

PMID:
15919137
[PubMed - indexed for MEDLINE]

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