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Items: 1 to 20 of 236

1.

[18F]FPhEP and [18F]F2PhEP, two new epibatidine-based radioligands: evaluation for imaging nicotinic acetylcholine receptors in baboon brain.

Valette H, Dollé F, Saba W, Roger G, Hinnen F, Coulon C, Ottaviani M, Syrota A, Bottlaender M.

Synapse. 2007 Sep;61(9):764-70.

PMID:
17568410
2.

Synthesis and radiosynthesis of [(18)F]FPhEP, a novel alpha(4)beta(2)-selective, epibatidine-based antagonist for PET imaging of nicotinic acetylcholine receptors.

Roger G, Saba W, Valette H, Hinnen F, Coulon C, Ottaviani M, Bottlaender M, Dollé F.

Bioorg Med Chem. 2006 Jun 1;14(11):3848-58. Epub 2006 Feb 7.

PMID:
16455259
3.

Synthesis and nicotinic acetylcholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: a new positron emission tomography ligand for nicotinic receptors.

Doll F, Dolci L, Valette H, Hinnen F, Vaufrey F, Guenther I, Fuseau C, Coulon C, Bottlaender M, Crouzel C.

J Med Chem. 1999 Jun 17;42(12):2251-9.

PMID:
10377231
4.

Imaging nicotinic acetylcholine receptors with fluorine-18-FPH, an epibatidine analog.

Villemagne VL, Horti A, Scheffel U, Ravert HT, Finley P, Clough DJ, London ED, Wagner HN Jr, Dannals RF.

J Nucl Med. 1997 Nov;38(11):1737-41.

5.

Fluorine-18-FPH for PET imaging of nicotinic acetylcholine receptors.

Horti A, Scheffel U, Stathis M, Finley P, Ravert HT, London ED, Dannals RF.

J Nucl Med. 1997 Aug;38(8):1260-5.

6.

18F-ZW-104: a new radioligand for imaging neuronal nicotinic acetylcholine receptors--in vitro binding properties and PET studies in baboons.

Valette H, Xiao Y, Peyronneau MA, Damont A, Kozikowski AP, Wei ZL, Kassiou M, Kellar KJ, Dollé F, Bottlaender M.

J Nucl Med. 2009 Aug;50(8):1349-55. doi: 10.2967/jnumed.108.061374.

7.

Synthesis of a fluorine-18 labeled derivative of epibatidine for in vivo nicotinic acetylcholine receptor PET imaging.

Dolci L, Dolle F, Valette H, Vaufrey F, Fuseau C, Bottlaender M, Crouzel C.

Bioorg Med Chem. 1999 Mar;7(3):467-79.

PMID:
10220033
8.

Imaging central nicotinic acetylcholine receptors in baboons with [18F]fluoro-A-85380.

Valette H, Bottlaender M, Dollé F, Guenther I, Fuseau C, Coulon C, Ottaviani M, Crouzel C.

J Nucl Med. 1999 Aug;40(8):1374-80.

9.

Synthesis and evaluation of nicotine alpha4beta2 receptor radioligand, 5-(3'-18F-fluoropropyl)-3-(2-(S)-pyrrolidinylmethoxy)pyridine, in rodents and PET in nonhuman primate.

Chattopadhyay S, Xue B, Collins D, Pichika R, Bagnera R, Leslie FM, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.

J Nucl Med. 2005 Jan;46(1):130-40.

10.

In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18F-fluoro-A-85380 and PET.

Gallezot JD, Bottlaender M, Grégoire MC, Roumenov D, Deverre JR, Coulon C, Ottaviani M, Dollé F, Syrota A, Valette H.

J Nucl Med. 2005 Feb;46(2):240-7.

11.

PET Imaging of nicotinic acetylcholine receptors in baboons with 18F-AZAN, a radioligand with improved brain kinetics.

Kuwabara H, Wong DF, Gao Y, Valentine H, Holt DP, Ravert HT, Dannals RF, Horti AG.

J Nucl Med. 2012 Jan;53(1):121-9. doi: 10.2967/jnumed.111.092338. Epub 2011 Dec 15.

12.

Synthesis of a [2-pyridinyl-18F]-labelled fluoro derivative of (-)-cytisine as a candidate radioligand for brain nicotinic alpha4beta2 receptor imaging with PET.

Roger G, Lagnel B, Rouden J, Besret L, Valette H, Demphel S, Gopisetti J, Coulon C, Ottaviani M, Wrenn LA, Letchworth SR, Bohme GA, Benavides J, Lasne MC, Bottlaender M, Dollé F.

Bioorg Med Chem. 2003 Dec 1;11(24):5333-43.

PMID:
14642577
13.

Pharmacological evaluation of a Br-76 analog of epibatidine: a potent ligand for studying brain nicotinic acetylcholine receptors.

Kassiou M, Bottlaender M, Loc'h C, Dolle F, Musachio JL, Coulon C, Ottaviani M, Dannals RF, Maziere B.

Synapse. 2002 Aug;45(2):95-104.

PMID:
12112402
14.

Characterization of the nicotinic ligand 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine in vivo.

Valette H, Bottlaender M, Dollé F, Guenther I, Coulon C, Hinnen F, Fuseau C, Ottaviani M, Crouzel C.

Life Sci. 1999;64(5):PL93-7.

PMID:
10072197
15.

Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors.

Gao Y, Horti AG, Kuwabara H, Ravert HT, Hilton J, Holt DP, Kumar A, Alexander M, Endres CJ, Wong DF, Dannals RF.

J Med Chem. 2007 Aug 9;50(16):3814-24. Epub 2007 Jul 13.

PMID:
17629263
16.
17.

Comparative studies of epibatidine derivatives [18F]NFEP and [18F]N-methyl-NFEP: kinetics, nicotine effect, and toxicity.

Ding YS, Molina PE, Fowler JS, Logan J, Volkow ND, Kuhar MJ, Carroll FI.

Nucl Med Biol. 1999 Jan;26(1):139-48.

PMID:
10096514
18.

Autoradiography of 2-[18F]F-A-85380 on nicotinic acetylcholine receptors in the porcine brain in vitro.

Deuther-Conrad W, Wevers A, Becker G, Schildan A, Patt M, Sabri O, Steinbach J, Brust P.

Synapse. 2006 Mar 15;59(4):201-10.

PMID:
16385508
19.

In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors.

Gündisch D, Koren AO, Horti AG, Pavlova OA, Kimes AS, Mukhin AG, London ED.

Synapse. 2005 Feb;55(2):89-97.

PMID:
15529332
20.

[125/123I]IPH: a radioiodinated analog of epibatidine for in vivo studies of nicotinic acetylcholine receptors.

Musachio JL, Villemagne VL, Scheffel U, Stathis M, Finley P, Horti A, London ED, Dannals RF.

Synapse. 1997 Aug;26(4):392-9.

PMID:
9215598
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