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Results: 1 to 20 of 141

1.

Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation.

Mahajan NP, Liu Y, Majumder S, Warren MR, Parker CE, Mohler JL, Earp HS, Whang YE.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8438-43. Epub 2007 May 9.

PMID:
17494760
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases.

Liu Y, Karaca M, Zhang Z, Gioeli D, Earp HS, Whang YE.

Oncogene. 2010 Jun 3;29(22):3208-16. doi: 10.1038/onc.2010.103. Epub 2010 Apr 12.

PMID:
20383201
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity.

Mahajan K, Challa S, Coppola D, Lawrence H, Luo Y, Gevariya H, Zhu W, Chen YA, Lawrence NJ, Mahajan NP.

Prostate. 2010 Sep 1;70(12):1274-85. doi: 10.1002/pros.21163.

PMID:
20623637
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer.

Mahajan K, Coppola D, Rawal B, Chen YA, Lawrence HR, Engelman RW, Lawrence NJ, Mahajan NP.

J Biol Chem. 2012 Jun 22;287(26):22112-22. doi: 10.1074/jbc.M112.357384. Epub 2012 May 7.

PMID:
22566699
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth.

Gregory CW, Whang YE, McCall W, Fei X, Liu Y, Ponguta LA, French FS, Wilson EM, Earp HS 3rd.

Clin Cancer Res. 2005 Mar 1;11(5):1704-12.

PMID:
15755991
[PubMed - indexed for MEDLINE]
Free Article
6.

Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox.

Mahajan NP, Whang YE, Mohler JL, Earp HS.

Cancer Res. 2005 Nov 15;65(22):10514-23.

PMID:
16288044
[PubMed - indexed for MEDLINE]
Free Article
7.

Growth hormone (GH) receptors in prostate cancer: gene expression in human tissues and cell lines and characterization, GH signaling and androgen receptor regulation in LNCaP cells.

Weiss-Messer E, Merom O, Adi A, Karry R, Bidosee M, Ber R, Kaploun A, Stein A, Barkey RJ.

Mol Cell Endocrinol. 2004 May 31;220(1-2):109-23.

PMID:
15196705
[PubMed - indexed for MEDLINE]
10.

Shepherding AKT and androgen receptor by Ack1 tyrosine kinase.

Mahajan K, Mahajan NP.

J Cell Physiol. 2010 Aug;224(2):327-33. doi: 10.1002/jcp.22162. Review.

PMID:
20432460
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.

Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M.

Cancer Res. 2004 Oct 1;64(19):7156-68.

PMID:
15466214
[PubMed - indexed for MEDLINE]
Free Article
12.

Inhibition of HER-2/neu kinase impairs androgen receptor recruitment to the androgen responsive enhancer.

Liu Y, Majumder S, McCall W, Sartor CI, Mohler JL, Gregory CW, Earp HS, Whang YE.

Cancer Res. 2005 Apr 15;65(8):3404-9.

PMID:
15833875
[PubMed - indexed for MEDLINE]
Free Article
13.

Inhibition of MAPK-signaling pathway promotes the interaction of the corepressor SMRT with the human androgen receptor and mediates repression of prostate cancer cell growth in the presence of antiandrogens.

Eisold M, Asim M, Eskelinen H, Linke T, Baniahmad A.

J Mol Endocrinol. 2009 May;42(5):429-35. doi: 10.1677/JME-08-0084. Epub 2009 Feb 17.

PMID:
19223455
[PubMed - indexed for MEDLINE]
Free Article
14.

Steroidogenic enzyme AKR1C3 is a novel androgen receptor-selective coactivator that promotes prostate cancer growth.

Yepuru M, Wu Z, Kulkarni A, Yin F, Barrett CM, Kim J, Steiner MS, Miller DD, Dalton JT, Narayanan R.

Clin Cancer Res. 2013 Oct 15;19(20):5613-25. doi: 10.1158/1078-0432.CCR-13-1151. Epub 2013 Aug 30.

PMID:
23995860
[PubMed - indexed for MEDLINE]
15.

The significance of Her2 on androgen receptor protein stability in the transition of androgen requirement in prostate cancer cells.

Hsu FN, Yang MS, Lin E, Tseng CF, Lin H.

Am J Physiol Endocrinol Metab. 2011 May;300(5):E902-8. doi: 10.1152/ajpendo.00610.2010. Epub 2011 Mar 1.

PMID:
21364123
[PubMed - indexed for MEDLINE]
Free Article
16.

Compensatory upregulation of tyrosine kinase Etk/BMX in response to androgen deprivation promotes castration-resistant growth of prostate cancer cells.

Dai B, Chen H, Guo S, Yang X, Linn DE, Sun F, Li W, Guo Z, Xu K, Kim O, Kong X, Melamed J, Qiu S, Chen H, Qiu Y.

Cancer Res. 2010 Jul 1;70(13):5587-96. doi: 10.1158/0008-5472.CAN-09-4610. Epub 2010 Jun 22.

PMID:
20570899
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

2,2-bis(4-chlorophenyl)-1,1-dichloroethylene stimulates androgen independence in prostate cancer cells through combinatorial activation of mutant androgen receptor and mitogen-activated protein kinase pathways.

Shah S, Hess-Wilson JK, Webb S, Daly H, Godoy-Tundidor S, Kim J, Boldison J, Daaka Y, Knudsen KE.

Mol Cancer Res. 2008 Sep;6(9):1507-20. doi: 10.1158/1541-7786.MCR-07-2166.

PMID:
18819937
[PubMed - indexed for MEDLINE]
Free Article
18.
19.

A competitive inhibitor that reduces recruitment of androgen receptor to androgen-responsive genes.

Cherian MT, Wilson EM, Shapiro DJ.

J Biol Chem. 2012 Jul 6;287(28):23368-80. doi: 10.1074/jbc.M112.344671. Epub 2012 May 15.

PMID:
22589544
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Sarcosine induces increase in HER2/neu expression in androgen-dependent prostate cancer cells.

Dahl M, Bouchelouche P, Kramer-Marek G, Capala J, Nordling J, Bouchelouche K.

Mol Biol Rep. 2011 Oct;38(7):4237-43. doi: 10.1007/s11033-010-0442-2. Epub 2011 Jul 14.

PMID:
21755295
[PubMed - indexed for MEDLINE]
Free PMC Article

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