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Results: 1 to 20 of 593

2.

Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity.

Busse D, Doughty RS, Ramsey TT, Russell WE, Price JO, Flanagan WM, Shawver LK, Arteaga CL.

J Biol Chem. 2000 Mar 10;275(10):6987-95.

PMID:
10702262
[PubMed - indexed for MEDLINE]
Free Article
3.

A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.

de La Motte Rouge T, Galluzzi L, Olaussen KA, Zermati Y, Tasdemir E, Robert T, Ripoche H, Lazar V, Dessen P, Harper F, Pierron G, Pinna G, Araujo N, Harel-Belan A, Armand JP, Wong TW, Soria JC, Kroemer G.

Cancer Res. 2007 Jul 1;67(13):6253-62.

PMID:
17616683
[PubMed - indexed for MEDLINE]
Free Article
4.

Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.

Di Gennaro E, Barbarino M, Bruzzese F, De Lorenzo S, Caraglia M, Abbruzzese A, Avallone A, Comella P, Caponigro F, Pepe S, Budillon A.

J Cell Physiol. 2003 Apr;195(1):139-50.

PMID:
12599217
[PubMed - indexed for MEDLINE]
5.

sst2 somatostatin receptor mediates cell cycle arrest and induction of p27(Kip1). Evidence for the role of SHP-1.

Pagès P, Benali N, Saint-Laurent N, Estève JP, Schally AV, Tkaczuk J, Vaysse N, Susini C, Buscail L.

J Biol Chem. 1999 May 21;274(21):15186-93.

PMID:
10329727
[PubMed - indexed for MEDLINE]
Free Article
6.

p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 function.

Liu S, Yamauchi H.

Cancer Lett. 2009 Dec 28;286(2):240-9. doi: 10.1016/j.canlet.2009.05.038. Epub 2009 Jul 23.

PMID:
19631451
[PubMed - indexed for MEDLINE]
7.

Effects of the combined blockade of EGFR and ErbB-2 on signal transduction and regulation of cell cycle regulatory proteins in breast cancer cells.

D'Alessio A, De Luca A, Maiello MR, Lamura L, Rachiglio AM, Napolitano M, Gallo M, Normanno N.

Breast Cancer Res Treat. 2010 Sep;123(2):387-96. doi: 10.1007/s10549-009-0649-x. Epub 2009 Nov 28.

PMID:
19946741
[PubMed - indexed for MEDLINE]
8.

HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.

Hirata A, Hosoi F, Miyagawa M, Ueda S, Naito S, Fujii T, Kuwano M, Ono M.

Cancer Res. 2005 May 15;65(10):4253-60.

PMID:
15899817
[PubMed - indexed for MEDLINE]
Free Article
10.

Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machinery.

Rodríguez-Ubreva FJ, Cariaga-Martinez AE, Cortés MA, Romero-De Pablos M, Ropero S, López-Ruiz P, Colás B.

Oncogene. 2010 Jan 21;29(3):345-55. doi: 10.1038/onc.2009.329. Epub 2009 Oct 19.

PMID:
19838216
[PubMed - indexed for MEDLINE]
11.

Anti-epidermal growth factor receptor monoclonal antibody 225 upregulates p27(KIP1) and p15(INK4B) and induces G1 arrest in oral squamous carcinoma cell lines.

Kiyota A, Shintani S, Mihara M, Nakahara Y, Ueyama Y, Matsumura T, Tachikawa T, Wong DT.

Oncology. 2002;63(1):92-8.

PMID:
12187077
[PubMed - indexed for MEDLINE]
12.

Combined treatment with erlotinib and a transforming growth factor-β type I receptor inhibitor effectively suppresses the enhanced motility of erlotinib-resistant non-small-cell lung cancer cells.

Serizawa M, Takahashi T, Yamamoto N, Koh Y.

J Thorac Oncol. 2013 Mar;8(3):259-69. doi: 10.1097/JTO.0b013e318279e942.

PMID:
23334091
[PubMed - indexed for MEDLINE]
13.

Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.

Sangfelt O, Erickson S, Castro J, Heiden T, Gustafsson A, Einhorn S, Grandér D.

Oncogene. 1999 May 6;18(18):2798-810.

PMID:
10362250
[PubMed - indexed for MEDLINE]
Free Article
14.

The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-Met inhibition.

Nakachi I, Naoki K, Soejima K, Kawada I, Watanabe H, Yasuda H, Nakayama S, Yoda S, Satomi R, Ikemura S, Terai H, Sato T, Ishizaka A.

Mol Cancer Res. 2010 Aug;8(8):1142-51. doi: 10.1158/1541-7786.MCR-09-0388. Epub 2010 Jul 20.

PMID:
20647329
[PubMed - indexed for MEDLINE]
Free Article
15.

BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.

Banerji L, Glassford J, Lea NC, Thomas NS, Klaus GG, Lam EW.

Oncogene. 2001 Nov 1;20(50):7352-67.

PMID:
11704865
[PubMed - indexed for MEDLINE]
Free Article
16.

Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.

Hsieh FF, Barnett LA, Green WF, Freedman K, Matushansky I, Skoultchi AI, Kelley LL.

Blood. 2000 Oct 15;96(8):2746-54.

PMID:
11023508
[PubMed - indexed for MEDLINE]
Free Article
17.

Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells.

Hsu SL, Hsu JW, Liu MC, Chen LY, Chang CD.

Exp Cell Res. 2000 Aug 1;258(2):322-31.

PMID:
10896783
[PubMed - indexed for MEDLINE]
18.
19.

BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells.

Andreu EJ, Lledó E, Poch E, Ivorra C, Albero MP, Martínez-Climent JA, Montiel-Duarte C, Rifón J, Pérez-Calvo J, Arbona C, Prósper F, Pérez-Roger I.

Cancer Res. 2005 Apr 15;65(8):3264-72.

PMID:
15833859
[PubMed - indexed for MEDLINE]
Free Article
20.

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells.

Roy S, Kaur M, Agarwal C, Tecklenburg M, Sclafani RA, Agarwal R.

Mol Cancer Ther. 2007 Oct;6(10):2696-707.

PMID:
17938263
[PubMed - indexed for MEDLINE]
Free Article
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