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OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.

Kovtun IV, Liu Y, Bjoras M, Klungland A, Wilson SH, McMurray CT.

Nature. 2007 May 24;447(7143):447-52. Epub 2007 Apr 22.


Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.

Goula AV, Berquist BR, Wilson DM 3rd, Wheeler VC, Trottier Y, Merienne K.

PLoS Genet. 2009 Dec;5(12):e1000749. doi: 10.1371/journal.pgen.1000749. Epub 2009 Dec 4.


Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo.

Kovtun IV, Johnson KO, McMurray CT.

Aging (Albany NY). 2011 May;3(5):509-14.


Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion.

Jarem DA, Wilson NR, Schermerhorn KM, Delaney S.

DNA Repair (Amst). 2011 Aug 15;10(8):887-96. doi: 10.1016/j.dnarep.2011.06.003. Epub 2011 Jul 2.


Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice.

Møllersen L, Rowe AD, Illuzzi JL, Hildrestrand GA, Gerhold KJ, Tveterås L, Bjølgerud A, Wilson DM 3rd, Bjørås M, Klungland A.

Hum Mol Genet. 2012 Nov 15;21(22):4939-47. doi: 10.1093/hmg/dds337. Epub 2012 Aug 21.


The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells.

de Souza-Pinto NC, Maynard S, Hashiguchi K, Hu J, Muftuoglu M, Bohr VA.

Mol Cell Biol. 2009 Aug;29(16):4441-54. doi: 10.1128/MCB.00265-09. Epub 2009 Jun 8.


Structure-dependent DNA damage and repair in a trinucleotide repeat sequence.

Jarem DA, Wilson NR, Delaney S.

Biochemistry. 2009 Jul 21;48(28):6655-63. doi: 10.1021/bi9007403.


CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.

Pal R, Ramdzan ZM, Kaur S, Duquette PM, Marcotte R, Leduy L, Davoudi S, Lamarche-Vane N, Iulianella A, Nepveu A.

J Biol Chem. 2015 Sep 11;290(37):22520-31. doi: 10.1074/jbc.M115.651042. Epub 2015 Jul 28.


Initiation of 8-oxoguanine base excision repair within trinucleotide tandem repeats.

Derevyanko AG, Endutkin AV, Ishchenko AA, Saparbaev MK, Zharkov DO.

Biochemistry (Mosc). 2012 Mar;77(3):270-9. doi: 10.1134/S0006297912030054.


Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.

Xu M, Lai Y, Torner J, Zhang Y, Zhang Z, Liu Y.

Nucleic Acids Res. 2014 Apr;42(6):3675-91. doi: 10.1093/nar/gkt1372. Epub 2014 Jan 14.


Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2.

Hailer MK, Slade PG, Martin BD, Rosenquist TA, Sugden KD.

DNA Repair (Amst). 2005 Jan 2;4(1):41-50.


Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1.

Rhee DB, Ghosh A, Lu J, Bohr VA, Liu Y.

DNA Repair (Amst). 2011 Jan 2;10(1):34-44. doi: 10.1016/j.dnarep.2010.09.008. Epub 2010 Oct 16.


Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.

Pinto RM, Dragileva E, Kirby A, Lloret A, Lopez E, St Claire J, Panigrahi GB, Hou C, Holloway K, Gillis T, Guide JR, Cohen PE, Li GM, Pearson CE, Daly MJ, Wheeler VC.

PLoS Genet. 2013 Oct;9(10):e1003930. doi: 10.1371/journal.pgen.1003930. Epub 2013 Oct 31.


The hOGG1 Ser326Cys polymorphism and Huntington's disease.

Coppedè F, Migheli F, Ceravolo R, Bregant E, Rocchi A, Petrozzi L, Unti E, Lonigro R, Siciliano G, Migliore L.

Toxicology. 2010 Dec 5;278(2):199-203. doi: 10.1016/j.tox.2009.10.019. Epub 2009 Oct 24.


Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.

Kovalenko M, Dragileva E, St Claire J, Gillis T, Guide JR, New J, Dong H, Kucherlapati R, Kucherlapati MH, Ehrlich ME, Lee JM, Wheeler VC.

PLoS One. 2012;7(9):e44273. doi: 10.1371/journal.pone.0044273. Epub 2012 Sep 7.


Alzheimer's disease-associated polymorphisms in human OGG1 alter catalytic activity and sensitize cells to DNA damage.

Jacob KD, Noren Hooten N, Tadokoro T, Lohani A, Barnes J, Evans MK.

Free Radic Biol Med. 2013 Oct;63:115-25. doi: 10.1016/j.freeradbiomed.2013.05.010. Epub 2013 May 14.


Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion.

Liu Y, Prasad R, Beard WA, Hou EW, Horton JK, McMurray CT, Wilson SH.

J Biol Chem. 2009 Oct 9;284(41):28352-66. doi: 10.1074/jbc.M109.050286. Epub 2009 Aug 11.


Activity of OGG1 variants in the repair of pro-oxidant-induced 8-oxo-2'-deoxyguanosine.

Smart DJ, Chipman JK, Hodges NJ.

DNA Repair (Amst). 2006 Nov 8;5(11):1337-45. Epub 2006 Jul 24.


Direct visualization of repair of oxidative damage by OGG1 in the nuclei of live cells.

Zielinska A, Davies OT, Meldrum RA, Hodges NJ.

J Biochem Mol Toxicol. 2011 Jan-Feb;25(1):1-7. doi: 10.1002/jbt.20346. Epub 2010 Nov 15.

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