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Results: 1 to 20 of 136

1.

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.

Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER 3rd, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ.

Nature. 2007 Apr 19;446(7138):876-81.

PMID:
17443180
[PubMed - indexed for MEDLINE]
2.

Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.

Reddy SK, Rape M, Margansky WA, Kirschner MW.

Nature. 2007 Apr 19;446(7138):921-5.

PMID:
17443186
[PubMed - indexed for MEDLINE]
3.

APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation.

Ge S, Skaar JR, Pagano M.

Cell Cycle. 2009 Jan 1;8(1):167-71. Epub 2009 Jan 11.

PMID:
19098431
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Orderly inactivation of the key checkpoint protein mitotic arrest deficient 2 (MAD2) during mitotic progression.

Ma HT, Poon RY.

J Biol Chem. 2011 Apr 15;286(15):13052-9. doi: 10.1074/jbc.M110.201897. Epub 2011 Feb 18.

PMID:
21335556
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding.

Kulukian A, Han JS, Cleveland DW.

Dev Cell. 2009 Jan;16(1):105-17. doi: 10.1016/j.devcel.2008.11.005.

PMID:
19154722
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

Nilsson J, Yekezare M, Minshull J, Pines J.

Nat Cell Biol. 2008 Dec;10(12):1411-20. doi: 10.1038/ncb1799. Epub 2008 Nov 9.

PMID:
18997788
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex.

Fang G.

Mol Biol Cell. 2002 Mar;13(3):755-66.

PMID:
11907259
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex.

Zich J, Sochaj AM, Syred HM, Milne L, Cook AG, Ohkura H, Rappsilber J, Hardwick KG.

Curr Biol. 2012 Feb 21;22(4):296-301. doi: 10.1016/j.cub.2011.12.049. Epub 2012 Jan 25.

PMID:
22281223
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation.

Izawa D, Pines J.

J Cell Biol. 2012 Oct 1;199(1):27-37. doi: 10.1083/jcb.201205170. Epub 2012 Sep 24.

PMID:
23007648
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly.

Eytan E, Sitry-Shevah D, Teichner A, Hershko A.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10568-73. doi: 10.1073/pnas.1308928110. Epub 2013 Jun 10.

PMID:
23754430
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia.

Zhang Y, van Deursen J, Galardy PJ.

PLoS One. 2011;6(8):e23389. doi: 10.1371/journal.pone.0023389. Epub 2011 Aug 11.

PMID:
21853124
[PubMed - indexed for MEDLINE]
Free PMC Article
12.
13.

Spindle checkpoint protein dynamics at kinetochores in living cells.

Howell BJ, Moree B, Farrar EM, Stewart S, Fang G, Salmon ED.

Curr Biol. 2004 Jun 8;14(11):953-64.

PMID:
15182668
[PubMed - indexed for MEDLINE]
Free Article
14.

Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis.

Sedgwick GG, Townsend K, Martin A, Shimwell NJ, Grand RJ, Stewart GS, Nilsson J, Turnell AS.

Oncogene. 2013 Sep 26;32(39):4622-33. doi: 10.1038/onc.2012.501. Epub 2012 Nov 19.

PMID:
23160376
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint.

Xia G, Luo X, Habu T, Rizo J, Matsumoto T, Yu H.

EMBO J. 2004 Aug 4;23(15):3133-43. Epub 2004 Jul 15.

PMID:
15257285
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex.

Herzog F, Primorac I, Dube P, Lenart P, Sander B, Mechtler K, Stark H, Peters JM.

Science. 2009 Mar 13;323(5920):1477-81. doi: 10.1126/science.1163300.

PMID:
19286556
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

Mansfeld J, Collin P, Collins MO, Choudhary JS, Pines J.

Nat Cell Biol. 2011 Sep 18;13(10):1234-43. doi: 10.1038/ncb2347.

PMID:
21926987
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31(comet).

Jia L, Li B, Warrington RT, Hao X, Wang S, Yu H.

Mol Biol Cell. 2011 Nov;22(22):4227-35. doi: 10.1091/mbc.E11-05-0389. Epub 2011 Sep 21.

PMID:
21937719
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Dual inhibition of Cdc20 by the spindle checkpoint.

Chen RH.

J Biomed Sci. 2007 Jul;14(4):475-9. Epub 2007 Mar 17. Review.

PMID:
17370142
[PubMed - indexed for MEDLINE]
20.

An E2 enzyme Ubc11 is required for ubiquitination of Slp1/Cdc20 and spindle checkpoint silencing in fission yeast.

Horikoshi Y, Habu T, Matsumoto T.

Cell Cycle. 2013 Mar 15;12(6):961-71. doi: 10.4161/cc.23946. Epub 2013 Feb 26.

PMID:
23442800
[PubMed - indexed for MEDLINE]
Free PMC Article

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