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Results: 1 to 20 of 111

1.

Cleavage and degradation of Claspin during apoptosis by caspases and the proteasome.

Semple JI, Smits VA, Fernaud JR, Mamely I, Freire R.

Cell Death Differ. 2007 Aug;14(8):1433-42. Epub 2007 Apr 13.

PMID:
17431426
[PubMed - indexed for MEDLINE]
Free Article
2.

Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway.

Clarke CA, Bennett LN, Clarke PR.

J Biol Chem. 2005 Oct 21;280(42):35337-45. Epub 2005 Aug 25.

PMID:
16123041
[PubMed - indexed for MEDLINE]
Free Article
3.

Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery.

Mamely I, van Vugt MA, Smits VA, Semple JI, Lemmens B, Perrakis A, Medema RH, Freire R.

Curr Biol. 2006 Oct 10;16(19):1950-5. Epub 2006 Aug 24.

PMID:
16934469
[PubMed - indexed for MEDLINE]
Free Article
4.

Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress.

Mailand N, Bekker-Jensen S, Bartek J, Lukas J.

Mol Cell. 2006 Aug 4;23(3):307-18.

PMID:
16885021
[PubMed - indexed for MEDLINE]
Free Article
5.

Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activation.

Bennett LN, Clarke PR.

FEBS Lett. 2006 Jul 24;580(17):4176-81. Epub 2006 Jul 5.

PMID:
16828751
[PubMed - indexed for MEDLINE]
Free Article
6.

HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.

Collis SJ, Barber LJ, Clark AJ, Martin JS, Ward JD, Boulton SJ.

Nat Cell Biol. 2007 Apr;9(4):391-401. Epub 2007 Mar 25.

PMID:
17384638
[PubMed - indexed for MEDLINE]
7.

Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin.

Spardy N, Covella K, Cha E, Hoskins EE, Wells SI, Duensing A, Duensing S.

Cancer Res. 2009 Sep 1;69(17):7022-9. doi: 10.1158/0008-5472.CAN-09-0925. Epub 2009 Aug 25.

PMID:
19706760
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Role of Claspin in regulation of nucleotide excision repair factor DDB2.

Praetorius-Ibba M, Wang QE, Wani G, El-Mahdy MA, Zhu Q, Qin S, Wani AA.

DNA Repair (Amst). 2007 May 1;6(5):578-87. Epub 2006 Dec 28.

PMID:
17196446
[PubMed - indexed for MEDLINE]
9.

Claspin is phosphorylated in the Chk1-binding domain by a kinase distinct from Chk1.

Bennett LN, Larkin C, Gillespie DA, Clarke PR.

Biochem Biophys Res Commun. 2008 May 9;369(3):973-6. doi: 10.1016/j.bbrc.2008.02.154. Epub 2008 Mar 10.

PMID:
18331829
[PubMed - indexed for MEDLINE]
10.

Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures.

Yoo HY, Jeong SY, Dunphy WG.

Genes Dev. 2006 Apr 1;20(7):772-83. Epub 2006 Mar 17.

PMID:
16547171
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells.

Nyormoi O, Wang Z, Doan D, Ruiz M, McConkey D, Bar-Eli M.

Mol Cell Biol. 2001 Aug;21(15):4856-67.

PMID:
11438643
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response.

Peschiaroli A, Dorrello NV, Guardavaccaro D, Venere M, Halazonetis T, Sherman NE, Pagano M.

Mol Cell. 2006 Aug 4;23(3):319-29.

PMID:
16885022
[PubMed - indexed for MEDLINE]
Free Article
13.

Cleavage and inactivation of ATM during apoptosis.

Smith GC, d'Adda di Fagagna F, Lakin ND, Jackson SP.

Mol Cell Biol. 1999 Sep;19(9):6076-84.

PMID:
10454555
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation.

Jakobi R, McCarthy CC, Koeppel MA, Stringer DK.

J Biol Chem. 2003 Oct 3;278(40):38675-85. Epub 2003 Jul 9.

PMID:
12853446
[PubMed - indexed for MEDLINE]
Free Article
15.

Chk1 and Claspin potentiate PCNA ubiquitination.

Yang XH, Shiotani B, Classon M, Zou L.

Genes Dev. 2008 May 1;22(9):1147-52. doi: 10.1101/gad.1632808.

PMID:
18451105
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

DNA-damage control: Claspin destruction turns off the checkpoint.

Gewurz BE, Harper JW.

Curr Biol. 2006 Nov 7;16(21):R932-4.

PMID:
17084694
[PubMed - indexed for MEDLINE]
Free Article
17.

Drf1-dependent kinase interacts with Claspin through a conserved protein motif.

Gold DA, Dunphy WG.

J Biol Chem. 2010 Apr 23;285(17):12638-46. doi: 10.1074/jbc.M109.077370. Epub 2010 Feb 27.

PMID:
20190277
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Human claspin is required for replication checkpoint control.

Chini CC, Chen J.

J Biol Chem. 2003 Aug 8;278(32):30057-62. Epub 2003 May 24.

PMID:
12766152
[PubMed - indexed for MEDLINE]
Free Article
19.

Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint.

Rainey MD, Harhen B, Wang GN, Murphy PV, Santocanale C.

Cell Cycle. 2013 May 15;12(10):1560-8. doi: 10.4161/cc.24675. Epub 2013 Apr 17.

PMID:
23598722
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome.

Virador VM, Davidson B, Czechowicz J, Mai A, Kassis J, Kohn EC.

PLoS One. 2009;4(4):e5136. doi: 10.1371/journal.pone.0005136. Epub 2009 Apr 8.

PMID:
19352495
[PubMed - indexed for MEDLINE]
Free PMC Article

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