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Items: 1 to 20 of 234

1.

Radical scavenging and cytochrome P450 3A4 inhibitory activity of bergaptol and geranylcoumarin from grapefruit.

Girennavar B, Jayaprakasha GK, Jadegoud Y, Nagana Gowda GA, Patil BS.

Bioorg Med Chem. 2007 Jun 1;15(11):3684-91. Epub 2007 Mar 18.

PMID:
17400460
2.

Potent inhibition of human cytochrome P450 3A4, 2D6, and 2C9 isoenzymes by grapefruit juice and its furocoumarins.

Girennavar B, Jayaprakasha GK, Patil BS.

J Food Sci. 2007 Oct;72(8):C417-21.

PMID:
17995595
3.

Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel.

Wangensteen H, Molden E, Christensen H, Malterud KE.

Eur J Clin Pharmacol. 2003 Feb;58(10):663-8. Epub 2003 Jan 30.

PMID:
12610742
4.

Furocoumarins from grapefruit juice and their effect on human CYP 3A4 and CYP 1B1 isoenzymes.

Girennavar B, Poulose SM, Jayaprakasha GK, Bhat NG, Patil BS.

Bioorg Med Chem. 2006 Apr 15;14(8):2606-12. Epub 2005 Dec 9.

PMID:
16338240
5.

Minor furanocoumarins and coumarins in grapefruit peel oil as inhibitors of human cytochrome P450 3A4.

C├ęsar TB, Manthey JA, Myung K.

J Nat Prod. 2009 Sep;72(9):1702-4. doi: 10.1021/np900266m.

PMID:
19689106
6.

Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.

Bailey DG, Dresser GK, Bend JR.

Clin Pharmacol Ther. 2003 Jun;73(6):529-37.

PMID:
12811362
7.
8.

Major furocoumarins in grapefruit juice II: phototoxicity, photogenotoxicity, and inhibitory potency vs. cytochrome P450 3A4 activity.

Messer A, Raquet N, Lohr C, Schrenk D.

Food Chem Toxicol. 2012 Mar;50(3-4):756-60. doi: 10.1016/j.fct.2011.11.023. Epub 2011 Dec 3.

PMID:
22155270
9.

6',7'-Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein.

Edwards DJ, Fitzsimmons ME, Schuetz EG, Yasuda K, Ducharme MP, Warbasse LH, Woster PM, Schuetz JD, Watkins P.

Clin Pharmacol Ther. 1999 Mar;65(3):237-44.

PMID:
10096255
10.

A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction.

Paine MF, Widmer WW, Hart HL, Pusek SN, Beavers KL, Criss AB, Brown SS, Thomas BF, Watkins PB.

Am J Clin Nutr. 2006 May;83(5):1097-105. Erratum in: Am J Clin Nutr. 2006 Jul;84(1):264.

11.

6'7'-Dihydroxybergamottin contributes to the grapefruit juice effect.

Kakar SM, Paine MF, Stewart PW, Watkins PB.

Clin Pharmacol Ther. 2004 Jun;75(6):569-79.

PMID:
15179411
12.

Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice.

Edwards DJ, Bellevue FH 3rd, Woster PM.

Drug Metab Dispos. 1996 Dec;24(12):1287-90.

PMID:
8971132
13.

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice.

He K, Iyer KR, Hayes RN, Sinz MW, Woolf TF, Hollenberg PF.

Chem Res Toxicol. 1998 Apr;11(4):252-9.

PMID:
9548795
15.

Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine.

Chan WK, Nguyen LT, Miller VP, Harris RZ.

Life Sci. 1998;62(10):PL135-42.

PMID:
9496718
16.

Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins.

Malhotra S, Bailey DG, Paine MF, Watkins PB.

Clin Pharmacol Ther. 2001 Jan;69(1):14-23.

PMID:
11180034
17.

Dihydroxybergamottin caproate as a potent and stable CYP3A4 inhibitor.

Ohta T, Nagahashi M, Hosoi S, Tsukamoto S.

Bioorg Med Chem. 2002 Apr;10(4):969-73.

PMID:
11836106
18.

Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds.

Ho PC, Saville DJ, Wanwimolruk S.

J Pharm Pharm Sci. 2001 Sep-Dec;4(3):217-27.

19.

Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition.

Paine MF, Criss AB, Watkins PB.

J Pharmacol Exp Ther. 2005 Mar;312(3):1151-60. Epub 2004 Oct 14.

20.

Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.

Ohnishi A, Matsuo H, Yamada S, Takanaga H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y.

Br J Pharmacol. 2000 Jul;130(6):1369-77.

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