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Results: 1 to 20 of 95

1.

Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers.

Rozenfeld R, Devi LA.

FASEB J. 2007 Aug;21(10):2455-65. Epub 2007 Mar 23.

PMID:
17384143
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Role of Src in ligand-specific regulation of delta-opioid receptor desensitization and internalization.

Hong MH, Xu C, Wang YJ, Ji JL, Tao YM, Xu XJ, Chen J, Xie X, Chi ZQ, Liu JG.

J Neurochem. 2009 Jan;108(1):102-14. doi: 10.1111/j.1471-4159.2008.05740.x. Epub 2008 Nov 10.

PMID:
19014372
[PubMed - indexed for MEDLINE]
3.

Selective interference of beta-arrestin 1 with kappa and delta but not mu opioid receptor/G protein coupling.

Cheng ZJ, Yu QM, Wu YL, Ma L, Pei G.

J Biol Chem. 1998 Sep 18;273(38):24328-33.

PMID:
9733719
[PubMed - indexed for MEDLINE]
Free Article
4.

Inhibition of EGF-induced ERK/MAP kinase-mediated astrocyte proliferation by mu opioids: integration of G protein and beta-arrestin 2-dependent pathways.

Miyatake M, Rubinstein TJ, McLennan GP, Belcheva MM, Coscia CJ.

J Neurochem. 2009 Jul;110(2):662-74. doi: 10.1111/j.1471-4159.2009.06156.x. Epub 2009 May 8.

PMID:
19457093
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity.

Gomes I, Fujita W, Gupta A, Saldanha SA, Negri A, Pinello CE, Eberhart C, Roberts E, Filizola M, Hodder P, Devi LA.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12072-7. doi: 10.1073/pnas.1222044110. Epub 2013 Jul 1. Erratum in: Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):1760. Saldanha, Adrian S [corrected to Saldanha, S Adrian]; Eberhart, Christina [added].

PMID:
23818586
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mu-opioid receptor knockout prevents changes in delta-opioid receptor trafficking induced by chronic inflammatory pain.

Morinville A, Cahill CM, Kieffer B, Collier B, Beaudet A.

Pain. 2004 Jun;109(3):266-73.

PMID:
15157687
[PubMed - indexed for MEDLINE]
7.

Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice.

Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A.

J Neurosci. 2003 Jun 15;23(12):4888-98.

PMID:
12832511
[PubMed - indexed for MEDLINE]
Free Article
8.

mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin.

Lowe JD, Celver JP, Gurevich VV, Chavkin C.

J Biol Chem. 2002 May 3;277(18):15729-35. Epub 2002 Feb 22.

PMID:
11861651
[PubMed - indexed for MEDLINE]
Free Article
9.

Beta-arrestin2 enhances beta2-adrenergic receptor-mediated nuclear translocation of ERK.

Kobayashi H, Narita Y, Nishida M, Kurose H.

Cell Signal. 2005 Oct;17(10):1248-53. Epub 2005 Feb 12.

PMID:
16038799
[PubMed - indexed for MEDLINE]
10.

Potentiation of μ-opioid receptor-mediated signaling by ketamine.

Gupta A, Devi LA, Gomes I.

J Neurochem. 2011 Oct;119(2):294-302. doi: 10.1111/j.1471-4159.2011.07361.x. Epub 2011 Sep 20.

PMID:
21692801
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors.

Rutherford JM, Wang J, Xu H, Dersch CM, Partilla JS, Rice KC, Rothman RB.

Peptides. 2008 Aug;29(8):1424-31. doi: 10.1016/j.peptides.2008.03.019. Epub 2008 Apr 8.

PMID:
18472184
[PubMed - indexed for MEDLINE]
13.

Opioid modulation of extracellular signal-regulated protein kinase activity is ras-dependent and involves Gbetagamma subunits.

Belcheva MM, Vogel Z, Ignatova E, Avidor-Reiss T, Zippel R, Levy R, Young EC, Barg J, Coscia CJ.

J Neurochem. 1998 Feb;70(2):635-45.

PMID:
9453557
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Heterodimerization of substance P and mu-opioid receptors regulates receptor trafficking and resensitization.

Pfeiffer M, Kirscht S, Stumm R, Koch T, Wu D, Laugsch M, Schröder H, Höllt V, Schulz S.

J Biol Chem. 2003 Dec 19;278(51):51630-7. Epub 2003 Oct 7.

PMID:
14532289
[PubMed - indexed for MEDLINE]
Free Article
15.

Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors.

Zhang X, Wang F, Chen X, Li J, Xiang B, Zhang YQ, Li BM, Ma L.

J Neurochem. 2005 Oct;95(1):169-78.

PMID:
16181421
[PubMed - indexed for MEDLINE]
16.

Serine 363 of the {delta}-opioid receptor is crucial for adopting distinct pathways to activate ERK1/2 in response to stimulation with different ligands.

Xu C, Hong MH, Zhang LS, Hou YY, Wang YH, Wang FF, Chen YJ, Xu XJ, Chen J, Xie X, Ma L, Chi ZQ, Liu JG.

J Cell Sci. 2010 Dec 15;123(Pt 24):4259-70. doi: 10.1242/jcs.073742. Epub 2010 Nov 23.

PMID:
21098639
[PubMed - indexed for MEDLINE]
Free Article
17.

mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis.

Hojo M, Sudo Y, Ando Y, Minami K, Takada M, Matsubara T, Kanaide M, Taniyama K, Sumikawa K, Uezono Y.

J Pharmacol Sci. 2008 Nov;108(3):308-19. Epub 2008 Nov 13.

PMID:
19008645
[PubMed - indexed for MEDLINE]
Free Article
18.

An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.

Groer CE, Tidgewell K, Moyer RA, Harding WW, Rothman RB, Prisinzano TE, Bohn LM.

Mol Pharmacol. 2007 Feb;71(2):549-57. Epub 2006 Nov 7.

PMID:
17090705
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia.

Gomes I, Gupta A, Filipovska J, Szeto HH, Pintar JE, Devi LA.

Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5135-9. Epub 2004 Mar 24.

PMID:
15044695
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

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