Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 156

1.

Does metronidazole interact with CYP3A substrates by inhibiting their metabolism through this metabolic pathway? Or should other mechanisms be considered?

Roedler R, Neuhauser MM, Penzak SR.

Ann Pharmacother. 2007 Apr;41(4):653-8. Epub 2007 Mar 20. Review. Erratum in: Ann Pharmacother. 2007 May;41(5):903.

PMID:
17374625
[PubMed - indexed for MEDLINE]
2.

Effects of metronidazole on midazolam metabolism in vitro and in vivo.

Wang JS, Backman JT, Kivistö KT, Neuvonen PJ.

Eur J Clin Pharmacol. 2000 Nov;56(8):555-9.

PMID:
11151744
[PubMed - indexed for MEDLINE]
3.

Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.

Allqvist A, Miura J, Bertilsson L, Mirghani RA.

Eur J Clin Pharmacol. 2007 Feb;63(2):173-9. Epub 2007 Jan 3.

PMID:
17200836
[PubMed - indexed for MEDLINE]
4.

Comparison of kinetic parameters for drug oxidation rates and substrate inhibition potential mediated by cytochrome P450 3A4 and 3A5.

Niwa T, Murayama N, Emoto C, Yamazaki H.

Curr Drug Metab. 2008 Jan;9(1):20-33. Review.

PMID:
18220568
[PubMed - indexed for MEDLINE]
5.

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.

Zhou S, Yung Chan S, Cher Goh B, Chan E, Duan W, Huang M, McLeod HL.

Clin Pharmacokinet. 2005;44(3):279-304. Review.

PMID:
15762770
[PubMed - indexed for MEDLINE]
6.

Alprazolam as an in vivo probe for studying induction of CYP3A in cynomolgus monkeys.

Ohtsuka T, Yoshikawa T, Kozakai K, Tsuneto Y, Uno Y, Utoh M, Yamazaki H, Kume T.

Drug Metab Dispos. 2010 Oct;38(10):1806-13. doi: 10.1124/dmd.110.032656. Epub 2010 Jun 28.

PMID:
20584745
[PubMed - indexed for MEDLINE]
Free Article
7.

Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro.

Amundsen R, Ã…sberg A, Ohm IK, Christensen H.

Drug Metab Dispos. 2012 Apr;40(4):655-61. doi: 10.1124/dmd.111.043018. Epub 2011 Dec 28.

PMID:
22205779
[PubMed - indexed for MEDLINE]
Free Article
8.

Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate.

Polasek TM, Miners JO.

Eur J Clin Pharmacol. 2006 Mar;62(3):203-8. Epub 2006 Jan 17.

PMID:
16416302
[PubMed - indexed for MEDLINE]
9.

Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.

Zhou SF.

Curr Drug Metab. 2008 May;9(4):310-22. Review.

PMID:
18473749
[PubMed - indexed for MEDLINE]
10.

Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.

Foti RS, Rock DA, Wienkers LC, Wahlstrom JL.

Drug Metab Dispos. 2010 Jun;38(6):981-7. doi: 10.1124/dmd.110.032094. Epub 2010 Mar 4.

PMID:
20203109
[PubMed - indexed for MEDLINE]
Free Article
11.

Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo.

Ring BJ, Patterson BE, Mitchell MI, Vandenbranden M, Gillespie J, Bedding AW, Jewell H, Payne CD, Forgue ST, Eckstein J, Wrighton SA, Phillips DL.

Clin Pharmacol Ther. 2005 Jan;77(1):63-75.

PMID:
15637532
[PubMed - indexed for MEDLINE]
12.

Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein.

Tachibana T, Kato M, Watanabe T, Mitsui T, Sugiyama Y.

Xenobiotica. 2009 Jun;39(6):430-43. doi: 10.1080/00498250902846252.

PMID:
19480549
[PubMed - indexed for MEDLINE]
13.

Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats.

Zhang W, Tan TM, Lim LY.

Drug Metab Dispos. 2007 Jan;35(1):110-5. Epub 2006 Oct 18.

PMID:
17050652
[PubMed - indexed for MEDLINE]
Free Article
14.

In vitro metabolism of the opioid tilidine and interaction of tilidine and nortilidine with CYP3A4, CYP2C19, and CYP2D6.

Weiss J, Sawa E, Riedel KD, Haefeli WE, Mikus G.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Sep;378(3):275-82. doi: 10.1007/s00210-008-0294-7. Epub 2008 May 31.

PMID:
18516595
[PubMed - indexed for MEDLINE]
15.

Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data.

Benet LZ, Cummins CL, Wu CY.

Curr Drug Metab. 2003 Oct;4(5):393-8. Review.

PMID:
14529371
[PubMed - indexed for MEDLINE]
16.

Drugs as CYP3A probes, inducers, and inhibitors.

Liu YT, Hao HP, Liu CX, Wang GJ, Xie HG.

Drug Metab Rev. 2007;39(4):699-721. Review.

PMID:
18058330
[PubMed - indexed for MEDLINE]
17.

A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and an in vitro study of the S-methyl metabolite of dalcetrapib.

Derks M, Fowler S, Kuhlmann O.

Clin Ther. 2009 Mar;31(3):586-99. doi: 10.1016/j.clinthera.2009.02.011.

PMID:
19393849
[PubMed - indexed for MEDLINE]
18.

The erythromycin breath test reflects P-glycoprotein function independently of cytochrome P450 3A activity.

Kurnik D, Wood AJ, Wilkinson GR.

Clin Pharmacol Ther. 2006 Sep;80(3):228-34.

PMID:
16952489
[PubMed - indexed for MEDLINE]
19.

Casopitant: in vitro data and SimCyp simulation to predict in vivo metabolic interactions involving cytochrome P450 3A4.

Motta P, Pons N, Pagliarusco S, Pellegatti M, Bonomo F.

Drug Metab Dispos. 2011 Mar;39(3):363-72. doi: 10.1124/dmd.110.035071. Epub 2010 Dec 13.

PMID:
21149541
[PubMed - indexed for MEDLINE]
Free Article
20.

Further characterization of a furanocoumarin-free grapefruit juice on drug disposition: studies with cyclosporine.

Paine MF, Widmer WW, Pusek SN, Beavers KL, Criss AB, Snyder J, Watkins PB.

Am J Clin Nutr. 2008 Apr;87(4):863-71.

PMID:
18400708
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk