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Items: 1 to 20 of 271


Loss of HSulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer.

Narita K, Chien J, Mullany SA, Staub J, Qian X, Lingle WL, Shridhar V.

J Biol Chem. 2007 May 11;282(19):14413-20. Epub 2007 Mar 15.


HSulf-1 inhibits angiogenesis and tumorigenesis in vivo.

Narita K, Staub J, Chien J, Meyer K, Bauer M, Friedl A, Ramakrishnan S, Shridhar V.

Cancer Res. 2006 Jun 15;66(12):6025-32.


Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.

Lai J, Chien J, Staub J, Avula R, Greene EL, Matthews TA, Smith DI, Kaufmann SH, Roberts LR, Shridhar V.

J Biol Chem. 2003 Jun 20;278(25):23107-17. Epub 2003 Apr 9.


WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth.

Matsuda Y, Schlange T, Oakeley EJ, Boulay A, Hynes NE.

Breast Cancer Res. 2009;11(3):R32. doi: 10.1186/bcr2317. Epub 2009 May 27.


HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

Uchimura K, Morimoto-Tomita M, Bistrup A, Li J, Lyon M, Gallagher J, Werb Z, Rosen SD.

BMC Biochem. 2006 Jan 17;7:2.


Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells.

Streicher KL, Willmarth NE, Garcia J, Boerner JL, Dewey TG, Ethier SP.

Mol Cancer Res. 2007 Aug;5(8):847-61. Epub 2007 Aug 1.


HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cells.

Khurana A, Liu P, Mellone P, Lorenzon L, Vincenzi B, Datta K, Yang B, Linhardt RJ, Lingle W, Chien J, Baldi A, Shridhar V.

Cancer Res. 2011 Mar 15;71(6):2152-61. doi: 10.1158/0008-5472.CAN-10-3059. Epub 2011 Jan 25.


A role for phospholipase C-gamma-mediated signaling in tumor cell invasion.

Kassis J, Moellinger J, Lo H, Greenberg NM, Kim HG, Wells A.

Clin Cancer Res. 1999 Aug;5(8):2251-60.


Efficient inhibition of an intraperitoneal xenograft model of human ovarian cancer by HSulf-1 gene delivered by biodegradable cationic heparin-polyethyleneimine nanogels.

Liu P, Gou M, Yi T, Xie C, Qi X, Zhou S, Deng H, Wei Y, Zhao X.

Oncol Rep. 2012 Feb;27(2):363-70. doi: 10.3892/or.2011.1550. Epub 2011 Nov 11.


HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.

Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD.

J Biol Chem. 2005 Dec 2;280(48):40066-73. Epub 2005 Sep 27.


Src family kinase inhibitors block amphiregulin-mediated autocrine ErbB signaling in normal human keratinocytes.

Kansra S, Stoll SW, Johnson JL, Elder JT.

Mol Pharmacol. 2005 Apr;67(4):1145-57. Epub 2004 Dec 22.


Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancer.

Cohen B, Shimizu M, Izrailit J, Ng NF, Buchman Y, Pan JG, Dering J, Reedijk M.

Breast Cancer Res Treat. 2010 Aug;123(1):113-24. doi: 10.1007/s10549-009-0621-9. Epub 2009 Nov 14.


Silencing of HSulf-2 expression in cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo.

Khurana A, McKean H, Kim H, Kim SH, mcguire J, Roberts LR, Goetz MP, Shridhar V.

Breast Cancer Res. 2012 Mar 12;14(2):R43.


HSULF-1 inhibits ERK and AKT signaling and decreases cell viability in vitro in human lung epithelial cells.

Zhang H, Newman DR, Sannes PL.

Respir Res. 2012 Aug 8;13:69. doi: 10.1186/1465-9921-13-69.


Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling.

Weng MS, Ho CT, Ho YS, Lin JK.

Toxicol Appl Pharmacol. 2007 Jan 15;218(2):107-18. Epub 2006 Nov 10.

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