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Results: 1 to 20 of 242

1.

Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs.

Pirot P, Naamane N, Libert F, Magnusson NE, Ørntoft TF, Cardozo AK, Eizirik DL.

Diabetologia. 2007 May;50(5):1006-14. Epub 2007 Mar 1.

PMID:
17333111
[PubMed - indexed for MEDLINE]
2.

Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms.

Pirot P, Eizirik DL, Cardozo AK.

Diabetologia. 2006 Jun;49(6):1229-36. Epub 2006 Apr 8.

PMID:
16604358
[PubMed - indexed for MEDLINE]
3.

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.

PMID:
17906960
[PubMed - indexed for MEDLINE]
4.

Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells.

Pirot P, Ortis F, Cnop M, Ma Y, Hendershot LM, Eizirik DL, Cardozo AK.

Diabetes. 2007 Apr;56(4):1069-77.

PMID:
17395747
[PubMed - indexed for MEDLINE]
Free Article
5.

Novel insights into the global proteome responses of insulin-producing INS-1E cells to different degrees of endoplasmic reticulum stress.

D'Hertog W, Maris M, Ferreira GB, Verdrengh E, Lage K, Hansen DA, Cardozo AK, Workman CT, Moreau Y, Eizirik DL, Waelkens E, Overbergh L, Mathieu C.

J Proteome Res. 2010 Oct 1;9(10):5142-52. doi: 10.1021/pr1004086.

PMID:
20839851
[PubMed - indexed for MEDLINE]
6.

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ.

Diabetologia. 2007 Apr;50(4):752-63. Epub 2007 Feb 1.

PMID:
17268797
[PubMed - indexed for MEDLINE]
7.

Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin.

Hartley T, Siva M, Lai E, Teodoro T, Zhang L, Volchuk A.

BMC Cell Biol. 2010 Jul 26;11:59. doi: 10.1186/1471-2121-11-59.

PMID:
20659334
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.

Ortis F, Pirot P, Naamane N, Kreins AY, Rasschaert J, Moore F, Théâtre E, Verhaeghe C, Magnusson NE, Chariot A, Orntoft TF, Eizirik DL.

Diabetologia. 2008 Jul;51(7):1213-25. doi: 10.1007/s00125-008-0999-7. Epub 2008 May 8.

PMID:
18463842
[PubMed - indexed for MEDLINE]
9.

Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.

Kutlu B, Cardozo AK, Darville MI, Kruhøffer M, Magnusson N, Ørntoft T, Eizirik DL.

Diabetes. 2003 Nov;52(11):2701-19.

PMID:
14578289
[PubMed - indexed for MEDLINE]
Free Article
10.

H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells.

Yang G, Yang W, Wu L, Wang R.

J Biol Chem. 2007 Jun 1;282(22):16567-76. Epub 2007 Apr 12.

PMID:
17430888
[PubMed - indexed for MEDLINE]
Free Article
11.

Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.

Riggs AC, Bernal-Mizrachi E, Ohsugi M, Wasson J, Fatrai S, Welling C, Murray J, Schmidt RE, Herrera PL, Permutt MA.

Diabetologia. 2005 Nov;48(11):2313-21. Epub 2005 Oct 8.

PMID:
16215705
[PubMed - indexed for MEDLINE]
12.

Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.

Lai E, Bikopoulos G, Wheeler MB, Rozakis-Adcock M, Volchuk A.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E540-50. doi: 10.1152/ajpendo.00478.2007. Epub 2008 Jan 15.

PMID:
18198352
[PubMed - indexed for MEDLINE]
Free Article
13.

Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis.

Casas S, Gomis R, Gribble FM, Altirriba J, Knuutila S, Novials A.

Diabetes. 2007 Sep;56(9):2284-94. Epub 2007 Jun 11.

PMID:
17563070
[PubMed - indexed for MEDLINE]
Free Article
14.

IL-1beta caused pancreatic beta-cells apoptosis is mediated in part by endoplasmic reticulum stress via the induction of endoplasmic reticulum Ca2+ release through the c-Jun N-terminal kinase pathway.

Wang Q, Zhang H, Zhao B, Fei H.

Mol Cell Biochem. 2009 Apr;324(1-2):183-90. doi: 10.1007/s11010-008-9997-9. Epub 2008 Dec 25.

PMID:
19109696
[PubMed - indexed for MEDLINE]
15.

Homocysteine-induced changes in mRNA levels of genes coding for cytoplasmic- and endoplasmic reticulum-resident stress proteins in neuronal cell cultures.

Althausen S, Paschen W.

Brain Res Mol Brain Res. 2000 Dec 8;84(1-2):32-40.

PMID:
11113529
[PubMed - indexed for MEDLINE]
16.

Endoplasmic reticulum stress induces Wfs1 gene expression in pancreatic beta-cells via transcriptional activation.

Ueda K, Kawano J, Takeda K, Yujiri T, Tanabe K, Anno T, Akiyama M, Nozaki J, Yoshinaga T, Koizumi A, Shinoda K, Oka Y, Tanizawa Y.

Eur J Endocrinol. 2005 Jul;153(1):167-76.

PMID:
15994758
[PubMed - indexed for MEDLINE]
Free Article
17.

Differential regulation of the endoplasmic reticulum stress response in pancreatic beta-cells exposed to long-chain saturated and monounsaturated fatty acids.

Diakogiannaki E, Welters HJ, Morgan NG.

J Endocrinol. 2008 Jun;197(3):553-63. doi: 10.1677/JOE-08-0041.

PMID:
18492819
[PubMed - indexed for MEDLINE]
Free Article
18.

Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells.

Kitiphongspattana K, Khan TA, Ishii-Schrade K, Roe MW, Philipson LH, Gaskins HR.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1543-54. Epub 2007 Jan 30.

PMID:
17264231
[PubMed - indexed for MEDLINE]
Free Article
19.

Impact of endoplasmic reticulum stress pathway on pancreatic beta-cells and diabetes mellitus.

Araki E, Oyadomari S, Mori M.

Exp Biol Med (Maywood). 2003 Nov;228(10):1213-7. Review.

PMID:
14610263
[PubMed - indexed for MEDLINE]
20.

Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger.

Guillemette T, van Peij N, Goosen T, Lanthaler K, Robson GD, van den Hondel CA, Stam H, Archer DB.

BMC Genomics. 2007 Jun 11;8:158.

PMID:
17561995
[PubMed - indexed for MEDLINE]
Free PMC Article

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