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17259873,17529859,19115971,18419539,19935447,18959493,16267772,19949357,18844684,18316986,18171247,19097840,19636285,18358662,21839135,18819966,19366362,19366365,17947966,17922399,21276441,23970485,23228356,19366363,15909260,21352937,19179034,18339522,16140686,12838672,23228353,18491947,20176669,22000087,19392883,17999974,19700359,11588694,19604721,17049211,17854472,16643530,19258924,15265832,16652275,17673477,16131518,17540542,22521846,23228355,20416266,20132251,19217998,15820983,24462930,23537554,20199759,19927039,18844690,17697316,22578763,15937758,15308357,24529940,23680440,12913778,18469733,9428584,24389158,20370508,19174454,24802765,19191622,19464534,12799510,15214879,20979849,19536041,18707553,19576637,21978670,25424794,11136262,20367225,23348816,18627249,17202908,16460546,17583392,20558247,21788714,18776825,21396531,28776337,16827713,17721369,23786942,26584056,22546719,21910891,19679235,22673142,12867838,15784306,26571373,17072121,18781875,22204595,24342249,23228358,17060695,29284419,15807381,16567980,15355410,18178388,17990224,14745695,24766085,15551214,14633369,16882291,18832131,26083590,19508165,25136018,15301674,23228352,18727804,20113175,24237437,15140858,27420806,23190779,15529269,26569193,16024234,19681946,25355940,21963873,21094423,20642870,15752529,16553916,18272956,26920470,20224541,19216062,17848875,15356776,24974272,21628304,15983908,15508501,19535383,18234877,19615960,23849332,19191605,17529860,27314035,21429682,16462300,11474429,17606677,24071028,18458650,22158567,18600192,21393143,19689466,26602268,19423491,15293896,18190701,23928466,21497634,19673968,21907527,20844463,24548097,24046219,23747454,12724479,16313770,24795223,18847402,16118046,11996682,17697443,21297521,22100892,19191614,24960150,19892529,17001845,18723327,27847379,11729519,21690620,14993532,16028155,17940232,23849314,18926673,26243258,19552985,27080766,21621576,18552897,19191611,18377994,22787364,15545856,16511389,22749798,26324014,17184290,16423493,10915080,20720416,16517889,22707105,22123697,20178139,32446777,31870586,15073163,23057516,28516842,27366006,29111412,22245497,15878444,20472027,16876978,20027125,28472614,20435707,23657529,22232285,26235372,11264032,15328116,21983212,7623880,24266666,11920317,23261044,23043378,11230456,12467543,20617352,17093012,19962156,16916725,19710581,21723357,28650416,15265831,16901591,9350093,17064274,19947881,33507135,23959308,28087317,15641266,21890767,21098526,28903506,12447737,28929957,16757594,29803821,18258121,20044050,16585644,12410477,16771912,15324545,28431817,28376809,12654736,28427991,20071233,18819983,19952861,24138693,25344177,11043072,23558320,16333099,21510746,16804429,31635974,10515818,19828490,21848708,15999006,9866434,19758792,16259643,20943207,16740811,26961592,26908787,23763847,16925096,8773670,16598044,19225097,24776520,23522635,17506919,29093321,19490958,23531034,36045056,30866853,16617552,26673859,22330126,8366829,25593104,12173128,20359560,28039377,11096005,15528684,9170700,17189091,31150842,31488088,24939685,12467542,27357587,22921813,15496389,29937245,21162625,17392436,24795228,11158138,11462184,11049766,16008622,11961958,28711387,22159491,14685452,16329681,28161295,31590932,15355420,16938419,22260780,22248318,24324221,25590837,22442292,16882290,25636183,17205472,28125588,16758412,32470194,30388168,11230444,21514939,19144940,29982572,3188210,19837717,30526145,19564254,15258000,26428194,20926218,28756964,32182260,21034194,15950288,17254463,15603993,20308373,28623109,15995047,8110402,30334707,28103262,15118910,9484256,11825007,31398980,19459987,20950338,17092618,32739491,11023465,12934179,18443117,22049827,20943819,15214878,23984273,20472403,10990272,27085174,21896350,23992851,23384407,1523077,28690025,24092845,16725302,27572394,25461243,25726037,21873379,23416655,21740830,18077618,27134492,28518018,30572022,21045368,21988450,16188350,28744663,10326798,14608266,16798688,12828156,24968052,21896349,15214880,20409693,14639539,17536934,11483833,11798929,10439539,18971356,27118458,28131730,18663502,23796611,23722433,21667000,25305566,10913397,29474258,20065057,16102653,30061027,17454891,6531496,21353946,27889249,12718807,23349853,21076929,19273677,14770075,32159507,17126867,15649990,21603602,15347911,21596081,11187442,11950115,21870053,23595388,11462175,1822151,29856703,12392662,28033345,28303826,16032557,23623384,20973240,15364451,21632898,31380301,21182994,28612153,26974749,21875450,21298844,21389591,30010393,11302833,10753730,21508171,16511752,21192863,23480525,19892480,29927374,10210308,10515817,15135501,21294383,25648240,24006139,31116101,27206423,29289385,10629012,25453309,31442868,14647555,16388429,18595984,16369663,31505644,25831418,21463396,16912938,15531597,26363404,19748932,16940064,21117969,27052283,18408957,17409214,16460553,16185459,26461259,15872231,30391398,23840728,24349263,22217305,12599075,25541296,25475124,17072272,17101260,20429715,8485280,8196139,35505649,23404685,16779850,27071529,23886767,17441533,11389489,17986268,25075961,25191941,15878263,22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Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States.

Farrell DJ, Klugman KP, Pichichero M. Farrell DJ, et al. Pediatr Infect Dis J. 2007 Feb;26(2):123-8. doi: 10.1097/01.inf.0000253059.84602.c3. Pediatr Infect Dis J. 2007. PMID: 17259873

Impact of the pneumococcal conjugate vaccine on serotype distribution and antimicrobial resistance of invasive Streptococcus pneumoniae isolates in Dallas, TX, children from 1999 through 2005.

Messina AF, Katz-Gaynor K, Barton T, Ahmad N, Ghaffar F, Rasko D, McCracken GH Jr. Messina AF, et al. Pediatr Infect Dis J. 2007 Jun;26(6):461-7. doi: 10.1097/INF.0b013e31805cdbeb. Pediatr Infect Dis J. 2007. PMID: 17529859

Changing epidemiology of antimicrobial-resistant Streptococcus pneumoniae in the United States, 2004-2005.

Richter SS, Heilmann KP, Dohrn CL, Riahi F, Beekmann SE, Doern GV. Richter SS, et al. Clin Infect Dis. 2009 Feb 1;48(3):e23-33. doi: 10.1086/595857. Clin Infect Dis. 2009. PMID: 19115971

Population snapshot of emergent Streptococcus pneumoniae serotype 19A in the United States, 2005.

Moore MR, Gertz RE Jr, Woodbury RL, Barkocy-Gallagher GA, Schaffner W, Lexau C, Gershman K, Reingold A, Farley M, Harrison LH, Hadler JL, Bennett NM, Thomas AR, McGee L, Pilishvili T, Brueggemann AB, Whitney CG, Jorgensen JH, Beall B. Moore MR, et al. J Infect Dis. 2008 Apr 1;197(7):1016-27. doi: 10.1086/528996. J Infect Dis. 2008. PMID: 18419539

Changing serotypes causing childhood invasive pneumococcal disease: Massachusetts, 2001-2007.

Hsu KK, Shea KM, Stevenson AE, Pelton SI; Massachusetts Department of Public Health. Hsu KK, et al. Pediatr Infect Dis J. 2010 Apr;29(4):289-93. doi: 10.1097/INF.0b013e3181c15471. Pediatr Infect Dis J. 2010. PMID: 19935447

Emergence of Streptococcus pneumoniae serotypes 19A, 6C, and 22F and serogroup 15 in Cleveland, Ohio, in relation to introduction of the protein-conjugated pneumococcal vaccine.

Jacobs MR, Good CE, Bajaksouzian S, Windau AR. Jacobs MR, et al. Clin Infect Dis. 2008 Dec 1;47(11):1388-95. doi: 10.1086/592972. Clin Infect Dis. 2008. PMID: 18959493

Postvaccine genetic structure of Streptococcus pneumoniae serotype 19A from children in the United States.

Pai R, Moore MR, Pilishvili T, Gertz RE, Whitney CG, Beall B; Active Bacterial Core Surveillance Team. Pai R, et al. J Infect Dis. 2005 Dec 1;192(11):1988-95. doi: 10.1086/498043. Epub 2005 Nov 1. J Infect Dis. 2005. PMID: 16267772

Epidemiology and evolution of invasive pneumococcal disease caused by multidrug resistant serotypes of 19A in the 8 years after implementation of pneumococcal conjugate vaccine immunization in Dallas, Texas.

Techasaensiri C, Messina AF, Katz K, Ahmad N, Huang R, McCracken GH Jr. Techasaensiri C, et al. Pediatr Infect Dis J. 2010 Apr;29(4):294-300. doi: 10.1097/INF.0b013e3181c2a229. Pediatr Infect Dis J. 2010. PMID: 19949357

Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine.

Aguiar SI, Serrano I, Pinto FR, Melo-Cristino J, Ramirez M; Portuguese Surveillance Group for the Study of Respiratory Pathogens. Aguiar SI, et al. Clin Microbiol Infect. 2008 Sep;14(9):835-43. doi: 10.1111/j.1469-0691.2008.02031.x. Clin Microbiol Infect. 2008. PMID: 18844684 Free article.

Impact of conjugate vaccine on transmission of antimicrobial-resistant Streptococcus pneumoniae among Alaskan children.

Park SY, Moore MR, Bruden DL, Hyde TB, Reasonover AL, Harker-Jones M, Rudolph KM, Hurlburt DA, Parks DJ, Parkinson AJ, Schuchat A, Hennessy TW. Park SY, et al. Pediatr Infect Dis J. 2008 Apr;27(4):335-40. doi: 10.1097/INF.0b013e318161434d. Pediatr Infect Dis J. 2008. PMID: 18316986

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