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Results: 1 to 20 of 94

1.

Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an "angiogenic switch".

Kay NE, Shanafelt TD, Strege AK, Lee YK, Bone ND, Raza A.

Leuk Res. 2007 Jul;31(7):899-906. Epub 2007 Jan 22.

PMID:
17241660
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells.

Lagneaux L, Delforge A, Bron D, De Bruyn C, Stryckmans P.

Blood. 1998 Apr 1;91(7):2387-96.

PMID:
9516138
[PubMed - indexed for MEDLINE]
Free Article
3.

Chronic lymphocytic leukemia cells induce anti-apoptotic effects of bone marrow stroma.

Plander M, Ugocsai P, Seegers S, Orsó E, Reichle A, Schmitz G, Hofstädter F, Brockhoff G.

Ann Hematol. 2011 Dec;90(12):1381-90. doi: 10.1007/s00277-011-1218-z. Epub 2011 Apr 5.

PMID:
21465189
[PubMed - indexed for MEDLINE]
4.

Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells.

Gehrke I, Gandhirajan RK, Poll-Wolbeck SJ, Hallek M, Kreuzer KA.

Mol Med. 2011;17(7-8):619-27. doi: 10.2119/molmed.2010.00210. Epub 2011 Apr 14.

PMID:
21519633
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Constitutive activation of the MAPkinase p38 is critical for MMP-9 production and survival of B-CLL cells on bone marrow stromal cells.

Ringshausen I, Dechow T, Schneller F, Weick K, Oelsner M, Peschel C, Decker T.

Leukemia. 2004 Dec;18(12):1964-70.

PMID:
15483673
[PubMed - indexed for MEDLINE]
6.

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance.

Kurtova AV, Balakrishnan K, Chen R, Ding W, Schnabl S, Quiroga MP, Sivina M, Wierda WG, Estrov Z, Keating MJ, Shehata M, Jäger U, Gandhi V, Kay NE, Plunkett W, Burger JA.

Blood. 2009 Nov 12;114(20):4441-50. doi: 10.1182/blood-2009-07-233718. Epub 2009 Sep 17.

PMID:
19762485
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells.

Secchiero P, Voltan R, di Iasio MG, Melloni E, Tiribelli M, Zauli G.

Clin Cancer Res. 2010 Mar 15;16(6):1824-33. doi: 10.1158/1078-0432.CCR-09-3031. Epub 2010 Mar 9.

PMID:
20215548
[PubMed - indexed for MEDLINE]
Free Article
8.

Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro.

Panayiotidis P, Jones D, Ganeshaguru K, Foroni L, Hoffbrand AV.

Br J Haematol. 1996 Jan;92(1):97-103.

PMID:
8562418
[PubMed - indexed for MEDLINE]
9.

Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1.

Burger JA, Tsukada N, Burger M, Zvaifler NJ, Dell'Aquila M, Kipps TJ.

Blood. 2000 Oct 15;96(8):2655-63.

PMID:
11023495
[PubMed - indexed for MEDLINE]
Free Article
10.

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch.

Ding W, Knox TR, Tschumper RC, Wu W, Schwager SM, Boysen JC, Jelinek DF, Kay NE.

Blood. 2010 Oct 21;116(16):2984-93. doi: 10.1182/blood-2010-02-269894. Epub 2010 Jul 6.

PMID:
20606160
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression.

Ghosh AK, Secreto CR, Knox TR, Ding W, Mukhopadhyay D, Kay NE.

Blood. 2010 Mar 4;115(9):1755-64. doi: 10.1182/blood-2009-09-242719. Epub 2009 Dec 17.

PMID:
20018914
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Serum levels of syndecan-1 in B-cell chronic lymphocytic leukemia: correlation with the extent of angiogenesis and disease-progression risk in early disease.

Molica S, Vitelli G, Mirabelli R, Digiesu G, Giannarelli D, Cuneo A, Ribatti D, Vacca A.

Leuk Lymphoma. 2006 Jun;47(6):1034-40.

PMID:
16840194
[PubMed - indexed for MEDLINE]
13.

Adhesion to bone marrow stroma inhibits apoptosis of chronic lymphocytic leukemia cells.

Lagneaux L, Delforge A, De Bruyn C, Bernier M, Bron D.

Leuk Lymphoma. 1999 Nov;35(5-6):445-53.

PMID:
10609782
[PubMed - indexed for MEDLINE]
14.

Increased bone marrow angiogenesis in B cell chronic lymphocytic leukemia.

Kini AR, Kay NE, Peterson LC.

Leukemia. 2000 Aug;14(8):1414-8.

PMID:
10942237
[PubMed - indexed for MEDLINE]
15.

Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target.

Hegde GV, Peterson KJ, Emanuel K, Mittal AK, Joshi AD, Dickinson JD, Kollessery GJ, Bociek RG, Bierman P, Vose JM, Weisenburger DD, Joshi SS.

Mol Cancer Res. 2008 Dec;6(12):1928-36. doi: 10.1158/1541-7786.MCR-08-0142.

PMID:
19074837
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma.

Ruan J, Hyjek E, Kermani P, Christos PJ, Hooper AT, Coleman M, Hempstead B, Leonard JP, Chadburn A, Rafii S.

Clin Cancer Res. 2006 Oct 1;12(19):5622-31.

PMID:
17020964
[PubMed - indexed for MEDLINE]
Free Article
18.

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia.

Shehata M, Schnabl S, Demirtas D, Hilgarth M, Hubmann R, Ponath E, Badrnya S, Lehner C, Hoelbl A, Duechler M, Gaiger A, Zielinski C, Schwarzmeier JD, Jaeger U.

Blood. 2010 Oct 7;116(14):2513-21. doi: 10.1182/blood-2009-10-248054. Epub 2010 Jun 24.

PMID:
20576813
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

Thioredoxin, produced by stromal cells retrieved from the lymph node microenvironment, rescues chronic lymphocytic leukemia cells from apoptosis in vitro.

Bäckman E, Bergh AC, Lagerdahl I, Rydberg B, Sundström C, Tobin G, Rosenquist R, Linderholm M, Rosén A.

Haematologica. 2007 Nov;92(11):1495-504.

PMID:
18024398
[PubMed - indexed for MEDLINE]
Free Article

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