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Results: 1 to 20 of 112

1.

The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy.

Karam JA, Fan J, Stanfield J, Richer E, Benaim EA, Frenkel E, Antich P, Sagalowsky AI, Mason RP, Hsieh JT.

Int J Cancer. 2007 Apr 15;120(8):1795-802.

PMID:
17230511
[PubMed - indexed for MEDLINE]
2.

Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivo.

Sasakawa Y, Naoe Y, Inoue T, Sasakawa T, Matsuo M, Manda T, Mutoh S.

Biochem Pharmacol. 2002 Oct 1;64(7):1079-90.

PMID:
12234611
[PubMed - indexed for MEDLINE]
3.

Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models.

Sasaki Y, Negishi H, Idogawa M, Suzuki H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T.

Mol Cancer Ther. 2008 Apr;7(4):779-87. doi: 10.1158/1535-7163.MCT-07-0395.

PMID:
18413792
[PubMed - indexed for MEDLINE]
Free Article
4.

The effects of the histone deacetylase inhibitor romidepsin (FK228) are enhanced by aspirin (ASA) in COX-1 positive ovarian cancer cells through augmentation of p21.

Son DS, Wilson AJ, Parl AK, Khabele D.

Cancer Biol Ther. 2010 Jun 1;9(11):928-35. Epub 2010 Jun 25.

PMID:
20404564
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression.

Nishida K, Komiyama T, Miyazawa S, Shen ZN, Furumatsu T, Doi H, Yoshida A, Yamana J, Yamamura M, Ninomiya Y, Inoue H, Asahara H.

Arthritis Rheum. 2004 Oct;50(10):3365-76.

PMID:
15476220
[PubMed - indexed for MEDLINE]
Free Article
6.

Low concentrations of the histone deacetylase inhibitor, depsipeptide, enhance the effects of gemcitabine and docetaxel in hormone refractory prostate cancer cells.

Kanzaki M, Kakinuma H, Kumazawa T, Inoue T, Saito M, Narita S, Yuasa T, Tsuchiya N, Habuchi T.

Oncol Rep. 2007 Apr;17(4):761-7.

PMID:
17342312
[PubMed - indexed for MEDLINE]
7.

Antitumor efficacy of FK228, a novel histone deacetylase inhibitor, depends on the effect on expression of angiogenesis factors.

Sasakawa Y, Naoe Y, Noto T, Inoue T, Sasakawa T, Matsuo M, Manda T, Mutoh S.

Biochem Pharmacol. 2003 Sep 15;66(6):897-906.

PMID:
12963476
[PubMed - indexed for MEDLINE]
8.

Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin.

Shang D, Liu Y, Matsui Y, Ito N, Nishiyama H, Kamoto T, Ogawa O.

Urology. 2008 Jun;71(6):1220-5. doi: 10.1016/j.urology.2007.11.029.

PMID:
18538698
[PubMed - indexed for MEDLINE]
9.

Histone deacetylase inhibitor FK228 activates tumor suppressor Prdx1 with apoptosis induction in esophageal cancer cells.

Hoshino I, Matsubara H, Hanari N, Mori M, Nishimori T, Yoneyama Y, Akutsu Y, Sakata H, Matsushita K, Seki N, Ochiai T.

Clin Cancer Res. 2005 Nov 1;11(21):7945-52.

PMID:
16278420
[PubMed - indexed for MEDLINE]
Free Article
10.

Effects of FK228, a novel histone deacetylase inhibitor, on tumor growth and expression of p21 and c-myc genes in vivo.

Sasakawa Y, Naoe Y, Inoue T, Sasakawa T, Matsuo M, Manda T, Mutoh S.

Cancer Lett. 2003 Jun 10;195(2):161-8.

PMID:
12767524
[PubMed - indexed for MEDLINE]
11.

Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228.

Yu X, Guo ZS, Marcu MG, Neckers L, Nguyen DM, Chen GA, Schrump DS.

J Natl Cancer Inst. 2002 Apr 3;94(7):504-13.

PMID:
11929951
[PubMed - indexed for MEDLINE]
Free Article
12.

Metformin synergistically enhances antitumor activity of histone deacetylase inhibitor trichostatin a against osteosarcoma cell line.

Duo J, Ma Y, Wang G, Han X, Zhang C.

DNA Cell Biol. 2013 Apr;32(4):156-64. doi: 10.1089/dna.2012.1926. Epub 2013 Mar 1.

PMID:
23451817
[PubMed - indexed for MEDLINE]
13.

Antitumor effects of histone deacetylase inhibitor on Ewing's family tumors.

Sakimura R, Tanaka K, Nakatani F, Matsunobu T, Li X, Hanada M, Okada T, Nakamura T, Matsumoto Y, Iwamoto Y.

Int J Cancer. 2005 Sep 20;116(5):784-92.

PMID:
15849726
[PubMed - indexed for MEDLINE]
14.

Proapoptotic ability of oncogenic H-Ras to facilitate apoptosis induced by histone deacetylase inhibitors in human cancer cells.

Choudhary S, Wang HC.

Mol Cancer Ther. 2007 Mar;6(3):1099-111.

PMID:
17363503
[PubMed - indexed for MEDLINE]
Free Article
15.

Lack of preventive efficacy of FK228, a histone deacetylase inhibitor, against N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in p53+/- and p53+/+ mice.

Wei M, Wanibuchi H, Morimura K, Salim EI, Moku M, Doi K, Mitsuhashi M, Masuda C, Shen J, Kinoshita A, Fukushima S.

Anticancer Res. 2004 Mar-Apr;24(2B):785-90.

PMID:
15161027
[PubMed - indexed for MEDLINE]
Free Article
16.

5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation.

Scott SA, Dong WF, Ichinohasama R, Hirsch C, Sheridan D, Sanche SE, Geyer CR, Decoteau JF.

Leuk Res. 2006 Jan;30(1):69-76. Epub 2005 Jul 25.

PMID:
16043219
[PubMed - indexed for MEDLINE]
17.

Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.

Liu Y, Salvador LA, Byeon S, Ying Y, Kwan JC, Law BK, Hong J, Luesch H.

J Pharmacol Exp Ther. 2010 Nov;335(2):351-61. doi: 10.1124/jpet.110.172387. Epub 2010 Aug 25.

PMID:
20739454
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Histone deacetylase inhibitor, FK228, induces apoptosis and suppresses cell proliferation of human glioblastoma cells in vitro and in vivo.

Sawa H, Murakami H, Kumagai M, Nakasato M, Yamauchi S, Matsuyama N, Tamura Y, Satone A, Ide W, Hashimoto I, Kamada H.

Acta Neuropathol. 2004 Jun;107(6):523-31. Epub 2004 Mar 16.

PMID:
15024582
[PubMed - indexed for MEDLINE]
19.

Potentiation of anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the cyclin-dependent kinase inhibitor P276-00 in human non-small-cell lung cancer cell lines.

Shirsath N, Rathos M, Chaudhari U, Sivaramakrishnan H, Joshi K.

Lung Cancer. 2013 Nov;82(2):214-21. doi: 10.1016/j.lungcan.2013.08.010. Epub 2013 Sep 3.

PMID:
24051085
[PubMed - indexed for MEDLINE]
20.

[Inhibitory effect of a novel histone deacetylases inhibitor FK228 on human colon cancer HCT-116 cells in vitro and in vivo].

Xu DB, Wang YL, Yue Y, Wu SC, Ding H.

Zhonghua Zhong Liu Za Zhi. 2013 Nov;35(11):814-8. Chinese.

PMID:
24447477
[PubMed - indexed for MEDLINE]

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