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Results: 1 to 20 of 104

1.

Hypoxia-inducible factors: central regulators of the tumor phenotype.

Gordan JD, Simon MC.

Curr Opin Genet Dev. 2007 Feb;17(1):71-7. Epub 2007 Jan 8. Review.

PMID:
17208433
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Feedback regulators of hypoxia-inducible factors and their role in cancer biology.

Henze AT, Acker T.

Cell Cycle. 2010 Jul 15;9(14):2749-63. Epub 2010 Jul 30.

PMID:
20603601
[PubMed - indexed for MEDLINE]
Free Article
3.

Biology of hypoxia-inducible factor-2alpha in development and disease.

Patel SA, Simon MC.

Cell Death Differ. 2008 Apr;15(4):628-34. doi: 10.1038/cdd.2008.17. Epub 2008 Feb 15. Review.

PMID:
18259197
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Hypoxia-inducible factor (HIF)-3alpha is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2.

Pasanen A, Heikkilä M, Rautavuoma K, Hirsilä M, Kivirikko KI, Myllyharju J.

Int J Biochem Cell Biol. 2010 Jul;42(7):1189-200. doi: 10.1016/j.biocel.2010.04.008. Epub 2010 Apr 21.

PMID:
20416395
[PubMed - indexed for MEDLINE]
5.

Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.

Aprelikova O, Wood M, Tackett S, Chandramouli GV, Barrett JC.

Cancer Res. 2006 Jun 1;66(11):5641-7.

PMID:
16740701
[PubMed - indexed for MEDLINE]
Free Article
6.

The HIF pathway: implications for patterns of gene expression in cancer.

Wykoff CC, Pugh CW, Harris AL, Maxwell PH, Ratcliffe PJ.

Novartis Found Symp. 2001;240:212-25; discussion 225-31. Review.

PMID:
11727931
[PubMed - indexed for MEDLINE]
7.
8.

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.

Cancer Res. 2001 Jul 1;61(13):5215-22.

PMID:
11431362
[PubMed - indexed for MEDLINE]
Free Article
10.

HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms.

Marín-Hernández A, Gallardo-Pérez JC, Ralph SJ, Rodríguez-Enríquez S, Moreno-Sánchez R.

Mini Rev Med Chem. 2009 Aug;9(9):1084-101. Review.

PMID:
19689405
[PubMed - indexed for MEDLINE]
11.

Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.

Anelli V, Gault CR, Cheng AB, Obeid LM.

J Biol Chem. 2008 Feb 8;283(6):3365-75. Epub 2007 Nov 30.

PMID:
18055454
[PubMed - indexed for MEDLINE]
Free Article
12.

Regulation of the chemokine receptor CXCR4 and metastasis by hypoxia-inducible factor in non small cell lung cancer cell lines.

Liu YL, Yu JM, Song XR, Wang XW, Xing LG, Gao BB.

Cancer Biol Ther. 2006 Oct;5(10):1320-6. Epub 2006 Oct 4.

PMID:
16929169
[PubMed - indexed for MEDLINE]
Free Article
13.

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation.

Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC.

Mol Cell Biol. 2003 Dec;23(24):9361-74.

PMID:
14645546
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

HIF-2alpha expression in human fetal paraganglia and neuroblastoma: relation to sympathetic differentiation, glucose deficiency, and hypoxia.

Nilsson H, Jögi A, Beckman S, Harris AL, Poellinger L, Påhlman S.

Exp Cell Res. 2005 Feb 15;303(2):447-56.

PMID:
15652356
[PubMed - indexed for MEDLINE]
15.

Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.

Catrina SB, Botusan IR, Rantanen A, Catrina AI, Pyakurel P, Savu O, Axelson M, Biberfeld P, Poellinger L, Brismar K.

Clin Cancer Res. 2006 Aug 1;12(15):4506-14.

PMID:
16899596
[PubMed - indexed for MEDLINE]
Free Article
16.

HIF-1α and HIF-2α correlate with migration and invasion in gastric cancer.

Wang Y, Li Z, Zhang H, Jin H, Sun L, Dong H, Xu M, Zhao P, Zhang B, Wang J, Pan Y, Liu L.

Cancer Biol Ther. 2010 Aug 15;10(4):376-82. Epub 2010 Aug 21.

PMID:
20559021
[PubMed - indexed for MEDLINE]
Free Article
18.

Hypoxia induced CCR7 expression via HIF-1alpha and HIF-2alpha correlates with migration and invasion in lung cancer cells.

Li Y, Qiu X, Zhang S, Zhang Q, Wang E.

Cancer Biol Ther. 2009 Feb;8(4):322-30. Epub 2009 Feb 3.

PMID:
19305150
[PubMed - indexed for MEDLINE]
Free Article
19.

HIF-1 inhibitors for cancer therapy: from gene expression to drug discovery.

Semenza GL.

Curr Pharm Des. 2009;15(33):3839-43. Review.

PMID:
19671047
[PubMed - indexed for MEDLINE]
20.

[Metastasis and hypoxia-inducible factor].

Kobayashi M, Nakagawa K.

Gan To Kagaku Ryoho. 2010 Nov;37(11):2047-51. Review. Japanese.

PMID:
21084801
[PubMed - indexed for MEDLINE]

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