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Results: 1 to 20 of 157

Similar articles for PubMed (Select 17190598)

1.

ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology.

Lam YC, Bowman AB, Jafar-Nejad P, Lim J, Richman R, Fryer JD, Hyun ED, Duvick LA, Orr HT, Botas J, Zoghbi HY.

Cell. 2006 Dec 29;127(7):1335-47.

2.

Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes.

Bowman AB, Lam YC, Jafar-Nejad P, Chen HK, Richman R, Samaco RC, Fryer JD, Kahle JJ, Orr HT, Zoghbi HY.

Nat Genet. 2007 Mar;39(3):373-9. Epub 2007 Feb 18.

PMID:
17322884
3.

Hosting neurotoxicity in polyglutamine disease.

Liu N, Bonini NM.

Cell. 2006 Dec 29;127(7):1299-300.

4.

Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1.

Lim J, Crespo-Barreto J, Jafar-Nejad P, Bowman AB, Richman R, Hill DE, Orr HT, Zoghbi HY.

Nature. 2008 Apr 10;452(7188):713-8. doi: 10.1038/nature06731. Epub 2008 Mar 12.

5.

Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua.

Fryer JD, Yu P, Kang H, Mandel-Brehm C, Carter AN, Crespo-Barreto J, Gao Y, Flora A, Shaw C, Orr HT, Zoghbi HY.

Science. 2011 Nov 4;334(6056):690-3. doi: 10.1126/science.1212673.

6.

Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.

Mizutani A, Wang L, Rajan H, Vig PJ, Alaynick WA, Thaler JP, Tsai CC.

EMBO J. 2005 Sep 21;24(18):3339-51. Epub 2005 Aug 25.

7.

Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.

Crespo-Barreto J, Fryer JD, Shaw CA, Orr HT, Zoghbi HY.

PLoS Genet. 2010 Jul 8;6(7):e1001021. doi: 10.1371/journal.pgen.1001021.

8.

Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua.

Kim E, Lu HC, Zoghbi HY, Song JJ.

Genes Dev. 2013 Mar 15;27(6):590-5. doi: 10.1101/gad.212068.112.

9.

USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.

Hong S, Kim SJ, Ka S, Choi I, Kang S.

Mol Cell Neurosci. 2002 Jun;20(2):298-306.

PMID:
12093161
10.

Amino acids in a region of ataxin-1 outside of the polyglutamine tract influence the course of disease in SCA1 transgenic mice.

Skinner PJ, Vierra-Green CA, Emamian E, Zoghbi HY, Orr HT.

Neuromolecular Med. 2002;1(1):33-42.

PMID:
12025814
11.

CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation.

Al-Ramahi I, Lam YC, Chen HK, de Gouyon B, Zhang M, Pérez AM, Branco J, de Haro M, Patterson C, Zoghbi HY, Botas J.

J Biol Chem. 2006 Sep 8;281(36):26714-24. Epub 2006 Jul 10.

12.

The ubiquitin-conjugating enzyme UbcH6 regulates the transcriptional repression activity of the SCA1 gene product ataxin-1.

Lee S, Hong S, Kang S.

Biochem Biophys Res Commun. 2008 Aug 8;372(4):735-40. doi: 10.1016/j.bbrc.2008.05.125. Epub 2008 Jun 2.

PMID:
18519031
14.

A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.

Sánchez I, Piñol P, Corral-Juan M, Pandolfo M, Matilla-Dueñas A.

Hum Mol Genet. 2013 Sep 1;22(17):3425-37. doi: 10.1093/hmg/ddt197. Epub 2013 Apr 29.

15.

Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.

Emamian ES, Kaytor MD, Duvick LA, Zu T, Tousey SK, Zoghbi HY, Clark HB, Orr HT.

Neuron. 2003 May 8;38(3):375-87.

PMID:
12741986
16.

A role for both wild-type and expanded ataxin-7 in transcriptional regulation.

Ström AL, Forsgren L, Holmberg M.

Neurobiol Dis. 2005 Dec;20(3):646-55. Epub 2005 Jun 3.

PMID:
15936949
17.

Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17.

Kim E, Lee Y, Choi S, Song JJ.

Biochem Biophys Res Commun. 2014 Jul 11;449(4):399-404. doi: 10.1016/j.bbrc.2014.05.063. Epub 2014 May 22.

PMID:
24858692
18.

dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1.

Al-Ramahi I, Pérez AM, Lim J, Zhang M, Sorensen R, de Haro M, Branco J, Pulst SM, Zoghbi HY, Botas J.

PLoS Genet. 2007 Dec 28;3(12):e234. doi: 10.1371/journal.pgen.0030234. Epub 2007 Nov 16.

19.

An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein.

Bergeron D, Lapointe C, Bissonnette C, Tremblay G, Motard J, Roucou X.

J Biol Chem. 2013 Jul 26;288(30):21824-35. doi: 10.1074/jbc.M113.472654. Epub 2013 Jun 12.

20.

The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.

Cvetanovic M, Rooney RJ, Garcia JJ, Toporovskaya N, Zoghbi HY, Opal P.

EMBO Rep. 2007 Jul;8(7):671-7. Epub 2007 Jun 8.

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