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Results: 1 to 20 of 89

1.

Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.

Hardy OT, Hohmeier HE, Becker TC, Manduchi E, Doliba NM, Gupta RK, White P, Stoeckert CJ Jr, Matschinsky FM, Newgard CB, Kaestner KH.

Mol Endocrinol. 2007 Mar;21(3):765-73. Epub 2006 Dec 21.

PMID:
17185391
[PubMed - indexed for MEDLINE]
2.

Role of medium- and short-chain L-3-hydroxyacyl-CoA dehydrogenase in the regulation of body weight and thermogenesis.

Schulz N, Himmelbauer H, Rath M, van Weeghel M, Houten S, Kulik W, Suhre K, Scherneck S, Vogel H, Kluge R, Wiedmer P, Joost HG, Schürmann A.

Endocrinology. 2011 Dec;152(12):4641-51. doi: 10.1210/en.2011-1547. Epub 2011 Oct 11.

PMID:
21990309
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.

Li C, Chen P, Palladino A, Narayan S, Russell LK, Sayed S, Xiong G, Chen J, Stokes D, Butt YM, Jones PM, Collins HW, Cohen NA, Cohen AS, Nissim I, Smith TJ, Strauss AW, Matschinsky FM, Bennett MJ, Stanley CA.

J Biol Chem. 2010 Oct 8;285(41):31806-18. doi: 10.1074/jbc.M110.123638. Epub 2010 Jul 29.

PMID:
20670938
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Specificity in beta cell expression of L-3-hydroxyacyl-CoA dehydrogenase, short chain, and potential role in down-regulating insulin release.

Martens GA, Vervoort A, Van de Casteele M, Stangé G, Hellemans K, Van Thi HV, Schuit F, Pipeleers D.

J Biol Chem. 2007 Jul 20;282(29):21134-44. Epub 2007 May 9.

PMID:
17491019
[PubMed - indexed for MEDLINE]
Free Article
5.

Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms.

Yang W, Yang G, Jia X, Wu L, Wang R.

J Physiol. 2005 Dec 1;569(Pt 2):519-31. Epub 2005 Sep 22.

PMID:
16179362
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Short-chain 3-hydroxyacyl-CoA dehydrogenase is a negative regulator of insulin secretion in response to fuel and non-fuel stimuli in INS832/13 β-cells.

Pepin E, Guay C, Delghingaro-Augusto V, Joly E, Madiraju SR, Prentki M.

J Diabetes. 2010 Sep;2(3):157-67. doi: 10.1111/j.1753-0407.2010.00076.x.

PMID:
20923481
[PubMed - indexed for MEDLINE]
7.

Foxa2 regulates multiple pathways of insulin secretion.

Lantz KA, Vatamaniuk MZ, Brestelli JE, Friedman JR, Matschinsky FM, Kaestner KH.

J Clin Invest. 2004 Aug;114(4):512-20.

PMID:
15314688
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with hyperinsulinism: a novel glucose-fatty acid cycle?

Eaton S, Chatziandreou I, Krywawych S, Pen S, Clayton PT, Hussain K.

Biochem Soc Trans. 2003 Dec;31(Pt 6):1137-9. Review.

PMID:
14641012
[PubMed - indexed for MEDLINE]
9.

Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion.

Clayton PT, Eaton S, Aynsley-Green A, Edginton M, Hussain K, Krywawych S, Datta V, Malingre HE, Berger R, van den Berg IE.

J Clin Invest. 2001 Aug;108(3):457-65.

PMID:
11489939
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

C16:0 sulfatide inhibits insulin secretion in rat beta-cells by reducing the sensitivity of KATP channels to ATP inhibition.

Buschard K, Blomqvist M, Månsson JE, Fredman P, Juhl K, Gromada J.

Diabetes. 2006 Oct;55(10):2826-34.

PMID:
17003349
[PubMed - indexed for MEDLINE]
Free Article
11.

BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.

Cosgrove KE, Antoine MH, Lee AT, Barnes PD, de Tullio P, Clayton P, McCloy R, De Lonlay P, Nihoul-Fékété C, Robert JJ, Saudubray JM, Rahier J, Lindley KJ, Hussain K, Aynsley-Green A, Pirotte B, Lebrun P, Dunne MJ.

J Clin Endocrinol Metab. 2002 Nov;87(11):4860-8.

PMID:
12414839
[PubMed - indexed for MEDLINE]
12.

Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

Straub SG, Cosgrove KE, Ammälä C, Shepherd RM, O'Brien RE, Barnes PD, Kuchinski N, Chapman JC, Schaeppi M, Glaser B, Lindley KJ, Sharp GW, Aynsley-Green A, Dunne MJ.

Diabetes. 2001 Feb;50(2):329-39.

PMID:
11272144
[PubMed - indexed for MEDLINE]
Free Article
13.

Role of aryl hydrocarbon receptor nuclear translocator in KATP channel-mediated insulin secretion in INS-1 insulinoma cells.

Kim JS, Zheng H, Kim SJ, Park JW, Park KS, Ho WK, Chun YS.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):1048-53. doi: 10.1016/j.bbrc.2009.01.004. Epub 2009 Jan 12.

PMID:
19141293
[PubMed - indexed for MEDLINE]
14.

Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cells.

Miyazaki S, Taniguchi H, Moritoh Y, Tashiro F, Yamamoto T, Yamato E, Ikegami H, Ozato K, Miyazaki J.

Diabetes. 2010 Nov;59(11):2854-61. doi: 10.2337/db09-1897. Epub 2010 Aug 26.

PMID:
20798333
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism.

Sato Y, Henquin JC.

Diabetes. 1998 Nov;47(11):1713-21.

PMID:
9792540
[PubMed - indexed for MEDLINE]
16.

Insights in congenital hyperinsulinism.

Hussain K.

Endocr Dev. 2007;11:106-21. Review.

PMID:
17986831
[PubMed - indexed for MEDLINE]
17.

Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

MacDonald PE, Sewing S, Wang J, Joseph JW, Smukler SR, Sakellaropoulos G, Wang J, Saleh MC, Chan CB, Tsushima RG, Salapatek AM, Wheeler MB.

J Biol Chem. 2002 Nov 22;277(47):44938-45. Epub 2002 Sep 20.

PMID:
12270920
[PubMed - indexed for MEDLINE]
Free Article
18.

Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion.

MacDonald PE, Ha XF, Wang J, Smukler SR, Sun AM, Gaisano HY, Salapatek AM, Backx PH, Wheeler MB.

Mol Endocrinol. 2001 Aug;15(8):1423-35.

PMID:
11463864
[PubMed - indexed for MEDLINE]
19.

Mechanisms of amino acid-stimulated insulin secretion in congenital hyperinsulinism.

Zhang T, Li C.

Acta Biochim Biophys Sin (Shanghai). 2013 Jan;45(1):36-43. doi: 10.1093/abbs/gms107. Epub 2012 Dec 4. Review.

PMID:
23212075
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan.

Chan SL, Mourtada M, Morgan NG.

Diabetes. 2001 Feb;50(2):340-7.

PMID:
11272145
[PubMed - indexed for MEDLINE]
Free Article
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