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Items: 1 to 20 of 194

1.

Targeting the Hedgehog pathway in cancer.

Rubin LL, de Sauvage FJ.

Nat Rev Drug Discov. 2006 Dec;5(12):1026-33. Review.

PMID:
17139287
2.

The Hedgehog pathway as a drug target in cancer therapy.

Lauth M, Toftgård R.

Curr Opin Investig Drugs. 2007 Jun;8(6):457-61. Review.

PMID:
17621875
3.

Hedgehog signalling as a target in cancer stem cells.

Medina V, Calvo MB, Díaz-Prado S, Espada J.

Clin Transl Oncol. 2009 Apr;11(4):199-207. Review.

PMID:
19380296
4.

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications.

Yang L, Xie G, Fan Q, Xie J.

Oncogene. 2010 Jan 28;29(4):469-81. doi: 10.1038/onc.2009.392. Epub 2009 Nov 23. Review.

PMID:
19935712
5.

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways.

Takebe N, Harris PJ, Warren RQ, Ivy SP.

Nat Rev Clin Oncol. 2011 Feb;8(2):97-106. doi: 10.1038/nrclinonc.2010.196. Epub 2010 Dec 14. Review.

PMID:
21151206
6.

Following the hedgehog to new cancer therapies.

Dlugosz AA, Talpaz M.

N Engl J Med. 2009 Sep 17;361(12):1202-5. doi: 10.1056/NEJMe0906092. Epub 2009 Sep 2. No abstract available.

PMID:
19726764
7.
8.

The role of hedgehog signalling in tumorigenesis.

Wicking C, McGlinn E.

Cancer Lett. 2001 Nov 8;173(1):1-7. Review.

PMID:
11578802
9.

Proteins of the Hedgehog signaling pathway as therapeutic targets against cancer.

Nehmé R, Mus-Veteau I.

Expert Rev Proteomics. 2010 Aug;7(4):601-12. doi: 10.1586/epr.10.39. Review.

PMID:
20653513
10.

Hedgehog signaling pathway: development of antagonists for cancer therapy.

Xie J.

Curr Oncol Rep. 2008 Mar;10(2):107-13. Review.

PMID:
18377823
11.

Targeting the hedgehog pathway: role in cancer and clinical implications of its inhibition.

Cohen DJ.

Hematol Oncol Clin North Am. 2012 Jun;26(3):565-88, viii. doi: 10.1016/j.hoc.2012.01.005. Review.

PMID:
22520980
12.

Mechanisms of Hedgehog signalling in cancer.

Marini KD, Payne BJ, Watkins DN, Martelotto LG.

Growth Factors. 2011 Dec;29(6):221-34. doi: 10.3109/08977194.2011.610756. Epub 2011 Aug 30. Review.

PMID:
21875383
13.

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

Scales SJ, de Sauvage FJ.

Trends Pharmacol Sci. 2009 Jun;30(6):303-12. doi: 10.1016/j.tips.2009.03.007. Epub 2009 May 13. Review.

PMID:
19443052
14.

Emerging mechanisms in morphogen-mediated axon guidance.

Sánchez-Camacho C, Bovolenta P.

Bioessays. 2009 Oct;31(10):1013-25. doi: 10.1002/bies.200900063. Review.

PMID:
19705365
15.

Dysregulation of Hedgehog, Wnt and Notch signalling pathways in breast cancer.

Zardawi SJ, O'Toole SA, Sutherland RL, Musgrove EA.

Histol Histopathol. 2009 Mar;24(3):385-98. Review.

PMID:
19130408
16.

Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors.

Queiroz KC, Spek CA, Peppelenbosch MP.

Drug Resist Updat. 2012 Aug;15(4):211-22. doi: 10.1016/j.drup.2012.05.002. Epub 2012 Aug 19. Review.

PMID:
22910179
17.

The hedgehog pathway as a therapeutic target for treatment of breast cancer.

Barginear MF, Leung M, Budman DR.

Breast Cancer Res Treat. 2009 Jul;116(2):239-46. doi: 10.1007/s10549-009-0423-0. Epub 2009 May 29. Review.

PMID:
19479372
18.

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy.

Lauth M, Toftgård R.

Cell Cycle. 2007 Oct 15;6(20):2458-63. Epub 2007 Jul 30. Review.

PMID:
17726373
19.

Advances in targeting the Hedgehog signaling pathway in cancer therapy.

Kiesslich T, Neureiter D.

Expert Opin Ther Targets. 2012 Feb;16(2):151-6. doi: 10.1517/14728222.2012.652948. Epub 2012 Jan 11.

PMID:
22233124
20.

Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer.

Yun JI, Kim HR, Park H, Kim SK, Lee J.

Arch Pharm Res. 2012 Aug;35(8):1317-33. doi: 10.1007/s12272-012-0801-8. Epub 2012 Sep 1. Review.

PMID:
22941475
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