Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 419

1.

Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate.

de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH Jr, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW.

J Biol Chem. 2007 Jan 26;282(4):2440-9. Epub 2006 Nov 22.

PMID:
17121835
[PubMed - indexed for MEDLINE]
Free Article
2.

Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications.

Poelarends GJ, Serrano H, Johnson WH Jr, Whitman CP.

Biochemistry. 2004 Jun 8;43(22):7187-96.

PMID:
15170356
[PubMed - indexed for MEDLINE]
3.

The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis.

Azurmendi HF, Wang SC, Massiah MA, Poelarends GJ, Whitman CP, Mildvan AS.

Biochemistry. 2004 Apr 13;43(14):4082-91.

PMID:
15065850
[PubMed - indexed for MEDLINE]
4.

Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases.

Poelarends GJ, Serrano H, Person MD, Johnson WH Jr, Murzin AG, Whitman CP.

Biochemistry. 2004 Jan 27;43(3):759-72.

PMID:
14730981
[PubMed - indexed for MEDLINE]
5.

Inactivation of Cg10062, a cis-3-chloroacrylic acid dehalogenase homologue in Corynebacterium glutamicum, by (R)- and (S)-oxirane-2-carboxylate: analysis and implications.

Robertson BA, Johnson WH, Lo HH Jr, Whitman CP.

Biochemistry. 2008 Aug 19;47(33):8796-803. doi: 10.1021/bi800790y. Epub 2008 Jul 23.

PMID:
18646866
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Characterization of a newly identified mycobacterial tautomerase with promiscuous dehalogenase and hydratase activities reveals a functional link to a recently diverged cis-3-chloroacrylic acid dehalogenase.

Baas BJ, Zandvoort E, Wasiel AA, Quax WJ, Poelarends GJ.

Biochemistry. 2011 Apr 12;50(14):2889-99. doi: 10.1021/bi200071k. Epub 2011 Mar 22.

PMID:
21370851
[PubMed - indexed for MEDLINE]
7.

Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Implications for the catalytic and inactivation mechanisms.

Guo Y, Serrano H, Johnson WH Jr, Ernst S, Hackert ML, Whitman CP.

Bioorg Chem. 2011 Feb;39(1):1-9. doi: 10.1016/j.bioorg.2010.10.001. Epub 2010 Oct 20.

PMID:
21074239
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A mutational analysis of the active site loop residues in cis-3-Chloroacrylic acid dehalogenase.

Schroeder GK, Huddleston JP, Johnson WH Jr, Whitman CP.

Biochemistry. 2013 Jun 18;52(24):4204-16. doi: 10.1021/bi4004414. Epub 2013 Jun 5.

PMID:
23692140
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily.

de Jong RM, Brugman W, Poelarends GJ, Whitman CP, Dijkstra BW.

J Biol Chem. 2004 Mar 19;279(12):11546-52. Epub 2003 Dec 29.

PMID:
14701869
[PubMed - indexed for MEDLINE]
Free Article
10.

Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity.

Pegan SD, Serrano H, Whitman CP, Mesecar AD.

Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1277-82. doi: 10.1107/S0907444908034707. Epub 2008 Nov 18.

PMID:
19018104
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase.

Harris TK, Czerwinski RM, Johnson WH Jr, Legler PM, Abeygunawardana C, Massiah MA, Stivers JT, Whitman CP, Mildvan AS.

Biochemistry. 1999 Sep 21;38(38):12343-57.

PMID:
10493802
[PubMed - indexed for MEDLINE]
12.

Reactions of trans-3-chloroacrylic acid dehalogenase with acetylene substrates: consequences of and evidence for a hydration reaction.

Wang SC, Person MD, Johnson WH Jr, Whitman CP.

Biochemistry. 2003 Jul 29;42(29):8762-73.

PMID:
12873137
[PubMed - indexed for MEDLINE]
13.
14.

Pre-steady-state kinetic analysis of cis-3-chloroacrylic acid dehalogenase: analysis and implications.

Robertson BA, Schroeder GK, Jin Z, Johnson KA, Whitman CP.

Biochemistry. 2009 Dec 15;48(49):11737-44. doi: 10.1021/bi901349z.

PMID:
19856961
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily.

Poelarends GJ, Serrano H, Person MD, Johnson WH Jr, Whitman CP.

Biochemistry. 2008 Aug 5;47(31):8139-47. doi: 10.1021/bi8007388. Epub 2008 Jul 4.

PMID:
18598055
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?

Poelarends GJ, Johnson WH Jr, Serrano H, Whitman CP.

Biochemistry. 2007 Aug 21;46(33):9596-604. Epub 2007 Jul 28.

PMID:
17661448
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural studies of the 1,3-dichloropropene catabolic enzymes.

Poelarends GJ, Whitman CP.

Bioorg Chem. 2004 Oct;32(5):376-92. Review.

PMID:
15381403
[PubMed - indexed for MEDLINE]
18.

Crystal structures of the wild-type, P1A mutant, and inactivated malonate semialdehyde decarboxylase: a structural basis for the decarboxylase and hydratase activities.

Almrud JJ, Poelarends GJ, Johnson WH Jr, Serrano H, Hackert ML, Whitman CP.

Biochemistry. 2005 Nov 15;44(45):14818-27.

PMID:
16274229
[PubMed - indexed for MEDLINE]
19.

A pre-steady state kinetic analysis of the αY60W mutant of trans-3-chloroacrylic acid dehalogenase: implications for the mechanism of the wild-type enzyme.

Huddleston JP, Schroeder GK, Johnson KA, Whitman CP.

Biochemistry. 2012 Nov 20;51(46):9420-35. doi: 10.1021/bi3010686. Epub 2012 Nov 8.

PMID:
23110338
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Catalytic role for arginine 188 in the C-C hydrolase catalytic mechanism for Escherichia coli MhpC and Burkholderia xenovorans LB400 BphD.

Li C, Li JJ, Montgomery MG, Wood SP, Bugg TD.

Biochemistry. 2006 Oct 17;45(41):12470-9.

PMID:
17029402
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk