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Results: 1 to 20 of 117

1.

Conformational restriction blocks glutamate receptor desensitization.

Weston MC, Schuck P, Ghosal A, Rosenmund C, Mayer ML.

Nat Struct Mol Biol. 2006 Dec;13(12):1120-7. Epub 2006 Nov 19.

PMID:
17115050
[PubMed - indexed for MEDLINE]
2.

Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.

Mayer ML, Olson R, Gouaux E.

J Mol Biol. 2001 Aug 24;311(4):815-36.

PMID:
11518533
[PubMed - indexed for MEDLINE]
3.

A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.

Holm MM, Naur P, Vestergaard B, Geballe MT, Gajhede M, Kastrup JS, Traynelis SF, Egebjerg J.

J Biol Chem. 2005 Oct 21;280(42):35469-76. Epub 2005 Aug 15.

PMID:
16103115
[PubMed - indexed for MEDLINE]
Free Article
4.

Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor.

Armstrong N, Jasti J, Beich-Frandsen M, Gouaux E.

Cell. 2006 Oct 6;127(1):85-97.

PMID:
17018279
[PubMed - indexed for MEDLINE]
Free Article
5.

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate.

Naur P, Vestergaard B, Skov LK, Egebjerg J, Gajhede M, Kastrup JS.

FEBS Lett. 2005 Feb 14;579(5):1154-60.

PMID:
15710405
[PubMed - indexed for MEDLINE]
Free Article
6.

Amino-acid residues involved in glutamate receptor 6 kainate receptor gating and desensitization.

Fleck MW, Cornell E, Mah SJ.

J Neurosci. 2003 Feb 15;23(4):1219-27.

PMID:
12598610
[PubMed - indexed for MEDLINE]
Free Article
7.

Mechanism of glutamate receptor desensitization.

Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E.

Nature. 2002 May 16;417(6886):245-53.

PMID:
12015593
[PubMed - indexed for MEDLINE]
8.

Crystal structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with L-glutamate: structural dissection of the ligand interaction and subunit interface.

Lee JH, Kang GB, Lim HH, Jin KS, Kim SH, Ree M, Park CS, Kim SJ, Eom SH.

J Mol Biol. 2008 Feb 15;376(2):308-16. doi: 10.1016/j.jmb.2007.10.081. Epub 2007 Nov 6.

PMID:
18164033
[PubMed - indexed for MEDLINE]
9.

Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core.

Hogner A, Kastrup JS, Jin R, Liljefors T, Mayer ML, Egebjerg J, Larsen IK, Gouaux E.

J Mol Biol. 2002 Sep 6;322(1):93-109.

PMID:
12215417
[PubMed - indexed for MEDLINE]
10.

cDNA cloning and functional properties of human glutamate receptor EAA3 (GluR5) in homomeric and heteromeric configuration.

Korczak B, Nutt SL, Fletcher EJ, Hoo KH, Elliott CE, Rampersad V, McWhinnie EA, Kamboj RK.

Receptors Channels. 1995;3(1):41-9.

PMID:
8589992
[PubMed - indexed for MEDLINE]
11.

Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6.

Zhang Y, Nayeem N, Nanao MH, Green T.

J Neurosci. 2006 Sep 27;26(39):10033-42.

PMID:
17005866
[PubMed - indexed for MEDLINE]
Free Article
12.

Conformational flexibility of the ligand-binding domain dimer in kainate receptor gating and desensitization.

Nayeem N, Mayans O, Green T.

J Neurosci. 2011 Feb 23;31(8):2916-24. doi: 10.1523/JNEUROSCI.4771-10.2011.

PMID:
21414913
[PubMed - indexed for MEDLINE]
Free Article
13.

Regulation of AMPA receptor gating by ligand binding core dimers.

Horning MS, Mayer ML.

Neuron. 2004 Feb 5;41(3):379-88.

PMID:
14766177
[PubMed - indexed for MEDLINE]
Free Article
14.

Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions.

Chaudhry C, Plested AJ, Schuck P, Mayer ML.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12329-34. doi: 10.1073/pnas.0904175106. Epub 2009 Jul 15.

PMID:
19617541
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Chemistry and conformation of the ligand-binding domain of GluR2 subtype of glutamate receptors.

Cheng Q, Jayaraman V.

J Biol Chem. 2004 Jun 18;279(25):26346-50. Epub 2004 Apr 20.

PMID:
15100219
[PubMed - indexed for MEDLINE]
Free Article
16.

Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.

Chaudhry C, Weston MC, Schuck P, Rosenmund C, Mayer ML.

EMBO J. 2009 May 20;28(10):1518-30. doi: 10.1038/emboj.2009.86. Epub 2009 Apr 2.

PMID:
19339989
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.

Hald H, Ahring PK, Timmermann DB, Liljefors T, Gajhede M, Kastrup JS.

J Mol Biol. 2009 Sep 4;391(5):906-17. doi: 10.1016/j.jmb.2009.07.002. Epub 2009 Jul 8.

PMID:
19591837
[PubMed - indexed for MEDLINE]
18.

A molecular envelope of the ligand-binding domain of a glutamate receptor in the presence and absence of agonist.

Abele R, Svergun D, Keinänen K, Koch MH, Madden DR.

Biochemistry. 1999 Aug 24;38(34):10949-57.

PMID:
10460150
[PubMed - indexed for MEDLINE]
19.

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.

Kunishima N, Shimada Y, Tsuji Y, Sato T, Yamamoto M, Kumasaka T, Nakanishi S, Jingami H, Morikawa K.

Nature. 2000 Oct 26;407(6807):971-7.

PMID:
11069170
[PubMed - indexed for MEDLINE]
20.

Identification of amino acid residues that control functional behavior in GluR5 and GluR6 kainate receptors.

Swanson GT, Gereau RW 4th, Green T, Heinemann SF.

Neuron. 1997 Oct;19(4):913-26.

PMID:
9354337
[PubMed - indexed for MEDLINE]
Free Article

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