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Results: 1 to 20 of 89

Similar articles for PubMed (Select 17114586)

1.

Hedgehog/Ras interactions regulate early stages of pancreatic cancer.

Pasca di Magliano M, Sekine S, Ermilov A, Ferris J, Dlugosz AA, Hebrok M.

Genes Dev. 2006 Nov 15;20(22):3161-73.

2.

Stromal response to Hedgehog signaling restrains pancreatic cancer progression.

Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3091-100. doi: 10.1073/pnas.1411679111. Epub 2014 Jul 14.

3.

Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancer.

Feldmann G, Karikari C, dal Molin M, Duringer S, Volkmann P, Bartsch DK, Bisht S, Koorstra JB, Brossart P, Maitra A, Fendrich V.

Cancer Biol Ther. 2011 Jun 1;11(11):959-68. Epub 2011 Jun 1.

4.

Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice.

Collins MA, Bednar F, Zhang Y, Brisset JC, Galbán S, Galbán CJ, Rakshit S, Flannagan KS, Adsay NV, Pasca di Magliano M.

J Clin Invest. 2012 Feb;122(2):639-53. doi: 10.1172/JCI59227. Epub 2012 Jan 9.

5.

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.

Tian H, Callahan CA, DuPree KJ, Darbonne WC, Ahn CP, Scales SJ, de Sauvage FJ.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4254-9. doi: 10.1073/pnas.0813203106. Epub 2009 Feb 25.

6.

Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.

Morton JP, Mongeau ME, Klimstra DS, Morris JP, Lee YC, Kawaguchi Y, Wright CV, Hebrok M, Lewis BC.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5103-8. Epub 2007 Mar 19.

7.

Stabilization of beta-catenin induces pancreas tumor formation.

Heiser PW, Cano DA, Landsman L, Kim GE, Kench JG, Klimstra DS, Taketo MM, Biankin AV, Hebrok M.

Gastroenterology. 2008 Oct;135(4):1288-300. doi: 10.1053/j.gastro.2008.06.089. Epub 2008 Jul 9.

8.

Trisomy of the Dscr1 gene suppresses early progression of pancreatic intraepithelial neoplasia driven by oncogenic Kras.

Lee JC, Shin J, Baek KH.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):50-5. doi: 10.1016/j.bbrc.2013.09.033. Epub 2013 Sep 13.

PMID:
24041692
9.

N-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer.

Su Y, Li J, Witkiewicz AK, Brennan D, Neill T, Talarico J, Radice GL.

Oncogene. 2012 Oct 11;31(41):4484-9. doi: 10.1038/onc.2011.574. Epub 2011 Dec 12.

10.

Shh signaling and pancreatic cancer: implications for therapy?

Morton JP, Lewis BC.

Cell Cycle. 2007 Jul 1;6(13):1553-7. Epub 2007 May 18. Review.

11.

Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts.

Walter K, Omura N, Hong SM, Griffith M, Vincent A, Borges M, Goggins M.

Clin Cancer Res. 2010 Mar 15;16(6):1781-9. doi: 10.1158/1078-0432.CCR-09-1913. Epub 2010 Mar 9.

12.

Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.

Prasad NB, Biankin AV, Fukushima N, Maitra A, Dhara S, Elkahloun AG, Hruban RH, Goggins M, Leach SD.

Cancer Res. 2005 Mar 1;65(5):1619-26.

13.

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.

Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M.

Nature. 2003 Oct 23;425(6960):851-6. Epub 2003 Sep 14.

14.
15.

Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma.

Damhofer H, Medema JP, Veenstra VL, Badea L, Popescu I, Roelink H, Bijlsma MF.

Mol Oncol. 2013 Dec;7(6):1031-42. doi: 10.1016/j.molonc.2013.08.004. Epub 2013 Aug 16.

16.

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.

Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL.

J Clin Invest. 2011 Oct;121(10):4106-17. doi: 10.1172/JCI42754. Epub 2011 Sep 19.

17.

Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo.

Qiu W, Sahin F, Iacobuzio-Donahue CA, Garcia-Carracedo D, Wang WM, Kuo CY, Chen D, Arking DE, Lowy AM, Hruban RH, Remotti HE, Su GH.

Oncotarget. 2011 Nov;2(11):862-73.

18.

Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects.

Adsay NV, Basturk O, Cheng JD, Andea AA.

Semin Radiat Oncol. 2005 Oct;15(4):254-64. Review.

PMID:
16183479
19.

Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice.

Grippo PJ, Fitchev PS, Bentrem DJ, Melstrom LG, Dangi-Garimella S, Krantz SB, Heiferman MJ, Chung C, Adrian K, Cornwell ML, Flesche JB, Rao SM, Talamonti MS, Munshi HG, Crawford SE.

Gut. 2012 Oct;61(10):1454-64. doi: 10.1136/gutjnl-2011-300821. Epub 2012 Jan 10.

PMID:
22234980
20.

Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway.

Li SH, Fu J, Watkins DN, Srivastava RK, Shankar S.

Mol Cell Biochem. 2013 Jan;373(1-2):217-27. doi: 10.1007/s11010-012-1493-6. Epub 2012 Nov 6.

PMID:
23129257
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