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J Am Geriatr Soc. 2006 Nov;54(11):1725-35.

Use of herbal medicine and other dietary supplements in community-dwelling older people: Baseline data from the ginkgo evaluation of memory study.

Author information

  • 1National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA. nahinr@mail.nih.gov

Abstract

OBJECTIVES:

To analyze baseline data from the Ginkgo Evaluation of Memory (GEM) study, in which information was collected on the use of all dietary supplements.

DESIGN:

Cross-sectional regression analysis.

SETTING:

GEM study sites in California, Maryland, North Carolina, and Pennsylvania.

PARTICIPANTS:

The GEM study enrolled 3,072 ambulatory individuals aged 75 and older between September 2000 and June 2002.

MEASUREMENTS:

Self-reported use of dietary supplements and use identified through bottles brought to the clinic.

RESULTS:

Respectively, 59.4%, 66.6%, and 27.4% of the GEM study cohort used a multivitamin, at least one individual vitamin or mineral supplement, and some type of nonvitamin/nonmineral dietary supplement (NVNMDS). In logistic regression models, multivitamin use was associated with female sex, a higher income, a higher modified Mini-Mental State Examination score, difficulty with mobility, and asthma history; use of any other vitamin or mineral was associated with female sex, white race, nonsmoking, more years of schooling, difficulty walking, a history of osteoporosis, and reading health and senior magazines; and NVNMDS use was associated with residing in California, having difficulties with muscle strength, and reading health and senior magazines.

CONCLUSION:

There were substantial differences between individuals who used vitamins and minerals and those who used NVNMDS. These data require that trial investigators pay close attention to participant use of off-protocol dietary supplements. In addition, these findings may help identify elderly individuals likely to combine NVNMDS and prescription drugs.

PMID:
17087700
[PubMed - indexed for MEDLINE]
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