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Results: 1 to 20 of 98

1.

Transcriptional interference among the murine beta-like globin genes.

Hu X, Eszterhas S, Pallazzi N, Bouhassira EE, Fields J, Tanabe O, Gerber SA, Bulger M, Engel JD, Groudine M, Fiering S.

Blood. 2007 Mar 1;109(5):2210-6. Epub 2006 Oct 31.

PMID:
17077320
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Promoters of the murine embryonic beta-like globin genes Ey and betah1 do not compete for interaction with the beta-globin locus control region.

Hu X, Bulger M, Roach JN, Eszterhas SK, Olivier E, Bouhassira EE, Groudine MT, Fiering S.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1111-5. Epub 2003 Jan 13. Erratum in: Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17251.

PMID:
12525692
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding.

Alhashem YN, Vinjamur DS, Basu M, Klingmüller U, Gaensler KM, Lloyd JA.

J Biol Chem. 2011 Jul 15;286(28):24819-27. doi: 10.1074/jbc.M111.247536. Epub 2011 May 24.

PMID:
21610079
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Mechanisms of developmental control of transcription in the murine alpha- and beta-globin loci.

Trimborn T, Gribnau J, Grosveld F, Fraser P.

Genes Dev. 1999 Jan 1;13(1):112-24.

PMID:
9887104
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene.

Tewari R, Gillemans N, Harper A, Wijgerde M, Zafarana G, Drabek D, Grosveld F, Philipsen S.

Development. 1996 Dec;122(12):3991-9.

PMID:
9012519
[PubMed - indexed for MEDLINE]
Free Article
6.

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ, Groudine M.

Genes Dev. 1995 Sep 15;9(18):2203-13.

PMID:
7557375
[PubMed - indexed for MEDLINE]
Free Article
7.

Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control region.

Tewari R, Gillemans N, Wijgerde M, Nuez B, von Lindern M, Grosveld F, Philipsen S.

EMBO J. 1998 Apr 15;17(8):2334-41.

PMID:
9545245
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.

Sawado T, Halow J, Bender MA, Groudine M.

Genes Dev. 2003 Apr 15;17(8):1009-18. Epub 2003 Apr 2.

PMID:
12672691
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Regulated expression of the human beta globin gene in transgenic mice requires an upstream globin or nonglobin promoter.

Anderson KP, Lloyd JA, Ponce E, Crable SC, Neumann JC, Lingrel JB.

Mol Biol Cell. 1993 Oct;4(10):1077-85.

PMID:
8298193
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CpG hypomethylation in a large domain encompassing the embryonic beta-like globin genes in primitive erythrocytes.

Hsu M, Mabaera R, Lowrey CH, Martin DI, Fiering S.

Mol Cell Biol. 2007 Jul;27(13):5047-54. Epub 2007 Apr 23.

PMID:
17452448
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes.

Schübeler D, Groudine M, Bender MA.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11432-7. Epub 2001 Sep 11.

PMID:
11553791
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Activation of beta-major globin gene transcription is associated with recruitment of NF-E2 to the beta-globin LCR and gene promoter.

Sawado T, Igarashi K, Groudine M.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10226-31. Epub 2001 Aug 21.

PMID:
11517325
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes.

Navas PA, Swank RA, Yu M, Peterson KR, Stamatoyannopoulos G.

Hum Mol Genet. 2003 Nov 15;12(22):2941-8. Epub 2003 Sep 23.

PMID:
14506128
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Differential requirement of a distal regulatory region for pre-initiation complex formation at globin gene promoters.

Ross J, Bottardi S, Bourgoin V, Wollenschlaeger A, Drobetsky E, Trudel M, Milot E.

Nucleic Acids Res. 2009 Sep;37(16):5295-308. doi: 10.1093/nar/gkp545. Epub 2009 Jun 30.

PMID:
19567738
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion.

Navas PA, Peterson KR, Li Q, Skarpidi E, Rohde A, Shaw SE, Clegg CH, Asano H, Stamatoyannopoulos G.

Mol Cell Biol. 1998 Jul;18(7):4188-96.

PMID:
9632803
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis.

Basu P, Lung TK, Lemsaddek W, Sargent TG, Williams DC Jr, Basu M, Redmond LC, Lingrel JB, Haar JL, Lloyd JA.

Blood. 2007 Nov 1;110(9):3417-25. Epub 2007 Aug 3.

PMID:
17675555
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.

Navas PA, Li Q, Peterson KR, Swank RA, Rohde A, Roy J, Stamatoyannopoulos G.

Hum Mol Genet. 2002 Apr 15;11(8):893-903.

PMID:
11971871
[PubMed - indexed for MEDLINE]
Free Article
19.

Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription.

Bender MA, Byron R, Ragoczy T, Telling A, Bulger M, Groudine M.

Blood. 2006 Aug 15;108(4):1395-401. Epub 2006 Apr 27.

PMID:
16645164
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Sequences located 3' to the breakpoint of the hereditary persistence of fetal hemoglobin-3 deletion exhibit enhancer activity and can modify the developmental expression of the human fetal A gamma-globin gene in transgenic mice.

Anagnou NP, Perez-Stable C, Gelinas R, Costantini F, Liapaki K, Constantopoulou M, Kosteas T, Moschonas NK, Stamatoyannopoulos G.

J Biol Chem. 1995 Apr 28;270(17):10256-63.

PMID:
7537267
[PubMed - indexed for MEDLINE]
Free Article

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