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Items: 1 to 20 of 100

1.

Structure of a heparin-dependent complex of Hedgehog and Ihog.

McLellan JS, Yao S, Zheng X, Geisbrecht BV, Ghirlando R, Beachy PA, Leahy DJ.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17208-13. Epub 2006 Oct 31.

2.

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.

McLellan JS, Zheng X, Hauk G, Ghirlando R, Beachy PA, Leahy DJ.

Nature. 2008 Oct 16;455(7215):979-83. doi: 10.1038/nature07358. Epub 2008 Sep 14.

3.

The ihog cell-surface proteins bind Hedgehog and mediate pathway activation.

Yao S, Lum L, Beachy P.

Cell. 2006 Apr 21;125(2):343-57.

4.

Genetic and biochemical definition of the Hedgehog receptor.

Zheng X, Mann RK, Sever N, Beachy PA.

Genes Dev. 2010 Jan 1;24(1):57-71. doi: 10.1101/gad.1870310.

5.

Ihog and Boi are essential for Hedgehog signaling in Drosophila.

Camp D, Currie K, Labbé A, van Meyel DJ, Charron F.

Neural Dev. 2010 Nov 2;5:28. doi: 10.1186/1749-8104-5-28.

6.

The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.

Avanesov A, Blair SS.

Development. 2013 Jan 1;140(1):107-16. doi: 10.1242/dev.078444. Epub 2012 Nov 15.

7.

Kinetic and structural studies on interactions between heparin or heparan sulfate and proteins of the hedgehog signaling pathway.

Zhang F, McLellan JS, Ayala AM, Leahy DJ, Linhardt RJ.

Biochemistry. 2007 Apr 3;46(13):3933-41. Epub 2007 Mar 10.

8.

Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand.

Camp D, Haitian He B, Li S, Althaus IW, Holtz AM, Allen BL, Charron F, van Meyel DJ.

Development. 2014 Oct;141(20):3879-88. doi: 10.1242/dev.103564. Epub 2014 Sep 17.

9.

Interactions between Hedgehog proteins and their binding partners come into view.

Beachy PA, Hymowitz SG, Lazarus RA, Leahy DJ, Siebold C.

Genes Dev. 2010 Sep 15;24(18):2001-12. doi: 10.1101/gad.1951710. Review.

10.

Drosophila miR-932 modulates hedgehog signaling by targeting its co-receptor Brother of ihog.

Gao L, Wu L, Hou X, Zhang Q, Zhang F, Ye X, Yang Y, Lin X.

Dev Biol. 2013 May 1;377(1):166-76. doi: 10.1016/j.ydbio.2013.02.002. Epub 2013 Feb 21.

11.

All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.

Kavran JM, Ward MD, Oladosu OO, Mulepati S, Leahy DJ.

J Biol Chem. 2010 Aug 6;285(32):24584-90. doi: 10.1074/jbc.M110.131680. Epub 2010 Jun 1.

12.

Balancing Hedgehog, a retention and release equilibrium given by Dally, Ihog, Boi and shifted/DmWif.

Bilioni A, Sánchez-Hernández D, Callejo A, Gradilla AC, Ibáñez C, Mollica E, Carmen Rodríguez-Navas M, Simon E, Guerrero I.

Dev Biol. 2013 Apr 15;376(2):198-212. doi: 10.1016/j.ydbio.2012.12.013. Epub 2012 Dec 29.

13.

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium.

Callejo A, Bilioni A, Mollica E, Gorfinkiel N, Andrés G, Ibáñez C, Torroja C, Doglio L, Sierra J, Guerrero I.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12591-8. doi: 10.1073/pnas.1106881108. Epub 2011 Jun 20.

14.

The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development.

Yan D, Wu Y, Yang Y, Belenkaya TY, Tang X, Lin X.

Development. 2010 Jun;137(12):2033-44. doi: 10.1242/dev.045740.

15.
16.

Cdon and Boc: Two transmembrane proteins implicated in cell-cell communication.

Sanchez-Arrones L, Cardozo M, Nieto-Lopez F, Bovolenta P.

Int J Biochem Cell Biol. 2012 May;44(5):698-702. doi: 10.1016/j.biocel.2012.01.019. Epub 2012 Feb 3. Review.

PMID:
22326621
17.

Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion.

Gradilla AC, González E, Seijo I, Andrés G, Bischoff M, González-Mendez L, Sánchez V, Callejo A, Ibáñez C, Guerra M, Ortigão-Farias JR, Sutherland JD, González M, Barrio R, Falcón-Pérez JM, Guerrero I.

Nat Commun. 2014 Dec 4;5:5649. doi: 10.1038/ncomms6649.

PMID:
25472772
18.

Detergent-solubilized Patched purified from Sf9 cells fails to interact strongly with cognate Hedgehog or Ihog homologs.

Cleveland TE 4th, McCabe JM, Leahy DJ.

Protein Expr Purif. 2014 Dec;104:92-102. doi: 10.1016/j.pep.2014.09.012. Epub 2014 Sep 26.

19.

Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling.

Kim MS, Saunders AM, Hamaoka BY, Beachy PA, Leahy DJ.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13112-7. doi: 10.1073/pnas.1109877108. Epub 2011 Jul 26.

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