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Results: 1 to 20 of 299

1.

Spinning disk confocal microscopy of live, intraerythrocytic malarial parasites. 1. Quantification of hemozoin development for drug sensitive versus resistant malaria.

Gligorijevic B, McAllister R, Urbach JS, Roepe PD.

Biochemistry. 2006 Oct 17;45(41):12400-10.

PMID:
17029396
[PubMed - indexed for MEDLINE]
2.

Spinning disk confocal microscopy of live, intraerythrocytic malarial parasites. 2. Altered vacuolar volume regulation in drug resistant malaria.

Gligorijevic B, Bennett T, McAllister R, Urbach JS, Roepe PD.

Biochemistry. 2006 Oct 17;45(41):12411-23.

PMID:
17029397
[PubMed - indexed for MEDLINE]
3.

Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy.

Gligorijevic B, Purdy K, Elliott DA, Cooper RA, Roepe PD.

Mol Biochem Parasitol. 2008 May;159(1):7-23. doi: 10.1016/j.molbiopara.2007.12.014. Epub 2008 Jan 9.

PMID:
18281110
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Chloroquine transport in Plasmodium falciparum. 1. Influx and efflux kinetics for live trophozoite parasites using a novel fluorescent chloroquine probe.

Cabrera M, Natarajan J, Paguio MF, Wolf C, Urbach JS, Roepe PD.

Biochemistry. 2009 Oct 13;48(40):9471-81. doi: 10.1021/bi901034r.

PMID:
19728740
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The effects of chloroquine and verapamil on digestive vacuolar pH of P. falciparum either sensitive or resistant to chloroquine.

Ursos LM, Dzekunov SM, Roepe PD.

Mol Biochem Parasitol. 2000 Sep;110(1):125-34.

PMID:
10989150
[PubMed - indexed for MEDLINE]
6.

Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine.

Dzekunov SM, Ursos LM, Roepe PD.

Mol Biochem Parasitol. 2000 Sep;110(1):107-24.

PMID:
10989149
[PubMed - indexed for MEDLINE]
7.

Glutathione transport: a new role for PfCRT in chloroquine resistance.

Patzewitz EM, Salcedo-Sora JE, Wong EH, Sethia S, Stocks PA, Maughan SC, Murray JA, Krishna S, Bray PG, Ward SA, Müller S.

Antioxid Redox Signal. 2013 Sep 1;19(7):683-95. doi: 10.1089/ars.2012.4625. Epub 2012 Dec 20.

PMID:
23256874
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH.

Bennett TN, Kosar AD, Ursos LM, Dzekunov S, Singh Sidhu AB, Fidock DA, Roepe PD.

Mol Biochem Parasitol. 2004 Jan;133(1):99-114.

PMID:
14668017
[PubMed - indexed for MEDLINE]
9.

Nonradioactive heteroduplex tracking assay for the detection of minority-variant chloroquine-resistant Plasmodium falciparum in Madagascar.

Juliano JJ, Randrianarivelojosia M, Ramarosandratana B, Ariey F, Mwapasa V, Meshnick SR.

Malar J. 2009 Mar 16;8:47. doi: 10.1186/1475-2875-8-47.

PMID:
19291288
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Malagashanine potentiates chloroquine antimalarial activity in drug resistant Plasmodium malaria by modifying both its efflux and influx.

Ramanitrahasimbola D, Rasoanaivo P, Ratsimamanga S, Vial H.

Mol Biochem Parasitol. 2006 Mar;146(1):58-67. Epub 2005 Nov 17.

PMID:
16313982
[PubMed - indexed for MEDLINE]
11.

Chloroquine transport in Plasmodium falciparum. 2. Analysis of PfCRT-mediated drug transport using proteoliposomes and a fluorescent chloroquine probe.

Paguio MF, Cabrera M, Roepe PD.

Biochemistry. 2009 Oct 13;48(40):9482-91. doi: 10.1021/bi901035j.

PMID:
19725576
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Role for the plasmodium falciparum digestive vacuole in chloroquine resistance.

Saliba KJ, Folb PI, Smith PJ.

Biochem Pharmacol. 1998 Aug 1;56(3):313-20.

PMID:
9744568
[PubMed - indexed for MEDLINE]
13.

Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum.

Mehlotra RK, Mattera G, Bockarie MJ, Maguire JD, Baird JK, Sharma YD, Alifrangis M, Dorsey G, Rosenthal PJ, Fryauff DJ, Kazura JW, Stoneking M, Zimmerman PA.

Antimicrob Agents Chemother. 2008 Jun;52(6):2212-22. doi: 10.1128/AAC.00089-08. Epub 2008 Apr 14.

PMID:
18411325
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum.

Sanchez CP, Stein WD, Lanzer M.

Trends Parasitol. 2007 Jul;23(7):332-9. Epub 2007 May 10. Review.

PMID:
17493873
[PubMed - indexed for MEDLINE]
15.

Hemozoin production by Plasmodium falciparum: variation with strain and exposure to chloroquine.

Orjih AU, Fitch CD.

Biochim Biophys Acta. 1993 Jul 11;1157(3):270-4.

PMID:
8323956
[PubMed - indexed for MEDLINE]
16.

In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin.

Sidhu AB, Sun Q, Nkrumah LJ, Dunne MW, Sacchettini JC, Fidock DA.

J Biol Chem. 2007 Jan 26;282(4):2494-504. Epub 2006 Nov 15.

PMID:
17110371
[PubMed - indexed for MEDLINE]
Free Article
17.

A verapamil-sensitive chloroquine-associated H+ leak from the digestive vacuole in chloroquine-resistant malaria parasites.

Lehane AM, Hayward R, Saliba KJ, Kirk K.

J Cell Sci. 2008 May 15;121(Pt 10):1624-32. doi: 10.1242/jcs.016758. Epub 2008 Apr 29.

PMID:
18445688
[PubMed - indexed for MEDLINE]
Free Article
18.

Quantitative pH measurements in Plasmodium falciparum-infected erythrocytes using pHluorin.

Kuhn Y, Rohrbach P, Lanzer M.

Cell Microbiol. 2007 Apr;9(4):1004-13.

PMID:
17381432
[PubMed - indexed for MEDLINE]
19.

Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria.

Ojurongbe O, Ogungbamigbe TO, Fagbenro-Beyioku AF, Fendel R, Kremsner PG, Kun JF.

Malar J. 2007 Apr 11;6:41.

PMID:
17428334
[PubMed - indexed for MEDLINE]
Free PMC Article

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