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Items: 1 to 20 of 115

1.

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth.

Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, Brem H, Folkman J.

Nature. 1990 Dec 6;348(6301):555-7.

PMID:
1701033
2.

Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent.

Kusaka M, Sudo K, Fujita T, Marui S, Itoh F, Ingber D, Folkman J.

Biochem Biophys Res Commun. 1991 Feb 14;174(3):1070-6.

PMID:
1705118
3.

Synthesis and biological evaluation of novel fumagillin and ovalicin analogues.

Mazitschek R, Huwe A, Giannis A.

Org Biomol Chem. 2005 Jun 7;3(11):2150-4. Epub 2005 Apr 22.

PMID:
15917904
4.

Fumagillin inhibits colorectal cancer growth and metastasis in mice: in vivo and in vitro study of anti-angiogenesis.

Hou L, Mori D, Takase Y, Meihua P, Kai K, Tokunaga O.

Pathol Int. 2009 Jul;59(7):448-61. doi: 10.1111/j.1440-1827.2009.02393.x.

PMID:
19563408
5.

Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.

Griffith EC, Su Z, Turk BE, Chen S, Chang YH, Wu Z, Biemann K, Liu JO.

Chem Biol. 1997 Jun;4(6):461-71.

PMID:
9224570
6.

Inhibitory effects of fumagillin and its analogue TNP-470 on the function, morphology and angiogenesis of an oestrogen-induced prolactinoma in Fischer 344 rats.

Stepień H, Grochal M, Zieliński KW, Mucha S, Kunert-Radek J, Kulig A, Stawowy A, Pisarek H.

J Endocrinol. 1996 Jul;150(1):99-106.

PMID:
8708569
7.

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth.

Fotsis T, Zhang Y, Pepper MS, Adlercreutz H, Montesano R, Nawroth PP, Schweigerer L.

Nature. 1994 Mar 17;368(6468):237-9.

PMID:
7511798
8.

Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2.

Griffith EC, Su Z, Niwayama S, Ramsay CA, Chang YH, Liu JO.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15183-8.

9.

Inhibitory effects of 9-(4-thio-beta-D-ribo-pentofuranosyl)guanine on tumor growth and angiogenesis.

Miura S, Yamada K, Kano F, Yoshimura Y.

Biol Pharm Bull. 2004 Apr;27(4):520-3.

10.

Combined effects of an angiogenesis inhibitor (TNP-470) and hyperthermia.

Nishimura Y, Murata R, Hiraoka M.

Br J Cancer. 1996 Feb;73(3):270-4.

11.

Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo.

Lu J, Chong CR, Hu X, Liu JO.

J Med Chem. 2006 Sep 21;49(19):5645-8.

PMID:
16970390
12.

Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors.

Lefkove B, Govindarajan B, Arbiser JL.

Expert Rev Anti Infect Ther. 2007 Aug;5(4):573-9. Review.

PMID:
17678422
13.

A re-evaluation of fumagillin selectivity towards endothelial cells.

Rodriguez-Nieto S, Medina MA, Quesada AR.

Anticancer Res. 2001 Sep-Oct;21(5):3457-60.

PMID:
11848509
14.

[On chance discovery in rational drug design. Aspergillus fumigatus and angiogenesis].

Klein C.

Pharm Unserer Zeit. 2007;36(6):450-1. Review. German.

PMID:
17957690
15.

Antitumour effect of a synthetic analogue of fumagillin on murine renal carcinoma.

Morita T, Shinohara N, Tokue A.

Br J Urol. 1994 Oct;74(4):416-21.

PMID:
7529632
16.

Inhibition of angiogenesis in vivo by interleukin 12.

Voest EE, Kenyon BM, O'Reilly MS, Truitt G, D'Amato RJ, Folkman J.

J Natl Cancer Inst. 1995 Apr 19;87(8):581-6.

PMID:
7538593
17.

Design, synthesis, and antiangiogenic effects of a series of potent novel fumagillin analogues.

Lee HW, Cho CS, Kang SK, Yoo YS, Shin JS, Ahn SK.

Chem Pharm Bull (Tokyo). 2007 Jul;55(7):1024-9.

18.
19.

Novel bicyclic oxazolone derivatives as anti-angiogenic agents.

Perron-Sierra FM, Pierré A, Burbridge M, Guilbaud N.

Bioorg Med Chem Lett. 2002 Jun 3;12(11):1463-6.

PMID:
12031320
20.

Design and synthesis of highly potent fumagillin analogues from homology modeling for a human MetAP-2.

Han CK, Ahn SK, Choi NS, Hong RK, Moon SK, Chun HS, Lee SJ, Kim JW, Hong CI, Kim D, Yoon JH, No KT.

Bioorg Med Chem Lett. 2000 Jan 3;10(1):39-43.

PMID:
10636239
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