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Items: 1 to 20 of 139

1.

Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells.

Waypa GB, Guzy R, Mungai PT, Mack MM, Marks JD, Roe MW, Schumacker PT.

Circ Res. 2006 Oct 27;99(9):970-8. Epub 2006 Sep 28.

2.

Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells.

Waypa GB, Marks JD, Guzy R, Mungai PT, Schriewer J, Dokic D, Schumacker PT.

Circ Res. 2010 Feb 19;106(3):526-35. doi: 10.1161/CIRCRESAHA.109.206334. Epub 2009 Dec 17.

3.

Hypoxia increases ROS signaling and cytosolic Ca(2+) in pulmonary artery smooth muscle cells of mouse lungs slices.

Desireddi JR, Farrow KN, Marks JD, Waypa GB, Schumacker PT.

Antioxid Redox Signal. 2010 Mar 1;12(5):595-602. doi: 10.1089/ars.2009.2862.

4.

Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes.

Waypa GB, Marks JD, Mack MM, Boriboun C, Mungai PT, Schumacker PT.

Circ Res. 2002 Oct 18;91(8):719-26.

5.

Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing.

Waypa GB, Chandel NS, Schumacker PT.

Circ Res. 2001 Jun 22;88(12):1259-66.

6.

Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation.

Waypa GB, Marks JD, Guzy RD, Mungai PT, Schriewer JM, Dokic D, Ball MK, Schumacker PT.

Am J Respir Crit Care Med. 2013 Feb 15;187(4):424-32. doi: 10.1164/rccm.201207-1294OC. Epub 2013 Jan 17.

7.

Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells.

Chi AY, Waypa GB, Mungai PT, Schumacker PT.

Antioxid Redox Signal. 2010 Mar 1;12(5):603-10. doi: 10.1089/ars.2009.2861.

8.

Mitochondrial ROS-PKCepsilon signaling axis is uniquely involved in hypoxic increase in [Ca2+]i in pulmonary artery smooth muscle cells.

Rathore R, Zheng YM, Li XQ, Wang QS, Liu QH, Ginnan R, Singer HA, Ho YS, Wang YX.

Biochem Biophys Res Commun. 2006 Dec 22;351(3):784-90. Epub 2006 Oct 30.

9.

Extracellular calcium-sensing receptor is critical in hypoxic pulmonary vasoconstriction.

Zhang J, Zhou J, Cai L, Lu Y, Wang T, Zhu L, Hu Q.

Antioxid Redox Signal. 2012 Aug 1;17(3):471-84. doi: 10.1089/ars.2011.4168. Epub 2012 Jan 25.

PMID:
22098336
10.

Role of mitochondrial reactive oxygen species in hypoxia-dependent increase in intracellular calcium in pulmonary artery myocytes.

Wang QS, Zheng YM, Dong L, Ho YS, Guo Z, Wang YX.

Free Radic Biol Med. 2007 Mar 1;42(5):642-53. Epub 2006 Dec 14.

11.

Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells.

Rathore R, Zheng YM, Niu CF, Liu QH, Korde A, Ho YS, Wang YX.

Free Radic Biol Med. 2008 Nov 1;45(9):1223-31. doi: 10.1016/j.freeradbiomed.2008.06.012. Epub 2008 Jun 21.

12.

Important role of PLC-γ1 in hypoxic increase in intracellular calcium in pulmonary arterial smooth muscle cells.

Yadav VR, Song T, Joseph L, Mei L, Zheng YM, Wang YX.

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 1;304(3):L143-51. doi: 10.1152/ajplung.00310.2012. Epub 2012 Nov 30.

13.

Sirtuin 3 deficiency does not augment hypoxia-induced pulmonary hypertension.

Waypa GB, Osborne SW, Marks JD, Berkelhamer SK, Kondapalli J, Schumacker PT.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):885-91. doi: 10.1165/rcmb.2013-0191OC.

14.

ROS-dependent signaling mechanisms for hypoxic Ca(2+) responses in pulmonary artery myocytes.

Wang YX, Zheng YM.

Antioxid Redox Signal. 2010 Mar 1;12(5):611-23. doi: 10.1089/ars.2009.2877. Review.

15.

Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells.

Farrow KN, Lee KJ, Perez M, Schriewer JM, Wedgwood S, Lakshminrusimha S, Smith CL, Steinhorn RH, Schumacker PT.

Antioxid Redox Signal. 2012 Aug 1;17(3):460-70. doi: 10.1089/ars.2011.4184. Epub 2012 Mar 8.

16.

Chronic hypoxia limits H2O2-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle.

Plomaritas DR, Herbert LM, Yellowhair TR, Resta TC, Gonzalez Bosc LV, Walker BR, Jernigan NL.

Am J Physiol Lung Cell Mol Physiol. 2014 Sep 1;307(5):L419-30. doi: 10.1152/ajplung.00095.2014. Epub 2014 Jul 3.

17.

Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.

Archer SL, Weir EK, Reeve HL, Michelakis E.

Adv Exp Med Biol. 2000;475:219-40. Review.

PMID:
10849663
18.

Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.

Michelakis ED, Thébaud B, Weir EK, Archer SL.

J Mol Cell Cardiol. 2004 Dec;37(6):1119-36. Review.

PMID:
15572043
19.

Hypoxic pulmonary vasoconstriction in the absence of pretone: essential role for intracellular Ca2+ release.

Connolly MJ, Prieto-Lloret J, Becker S, Ward JP, Aaronson PI.

J Physiol. 2013 Sep 15;591(18):4473-98. doi: 10.1113/jphysiol.2013.253682. Epub 2013 Jun 17.

20.

Hypoxic neonatal pulmonary arterial myocytes are sensitized to ROS-generated 8-isoprostane.

Gong Y, Yi M, Fediuk J, Lizotte PP, Dakshinamurti S.

Free Radic Biol Med. 2010 Apr 1;48(7):882-94. doi: 10.1016/j.freeradbiomed.2010.01.009. Epub 2010 Jan 14.

PMID:
20079425
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