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Results: 1 to 20 of 132

1.

Synthesis, aerobic cytotoxicity, and radiosensitizing activity of novel 2,4-dinitrophenylamine tethered 5-fluorouracil and hydroxyurea.

Khalaj A, Doroudi AR, Ostad SN, Khoshayand MR, Babai M, Adibpour N.

Bioorg Med Chem Lett. 2006 Dec 1;16(23):6034-8. Epub 2006 Sep 20.

PMID:
16990003
[PubMed - indexed for MEDLINE]
2.

Synthesis, in vitro cytotoxicity and radiosensitizing activity of novel 3-[(2,4-dinitrophenylamino)alkyl] derivatives of 5-fluorouracil.

Khalaj A, Abdi K, Ostad SN, Khoshayand MR, Lamei N, Nedaie HA.

Chem Biol Drug Des. 2014 Feb;83(2):183-90. doi: 10.1111/cbdd.12211. Epub 2013 Oct 4.

PMID:
23964692
[PubMed - indexed for MEDLINE]
3.

Synthesis and activity of novel nitropyrazines for use as hypoxic cell radiosensitizers.

Hartman GD, Hartman RD, Schwering JE, Saari WS, Engelhardt EL, Jones NR, Wardman P, Watts ME, Woodcock M.

J Med Chem. 1984 Dec;27(12):1634-9.

PMID:
6389865
[PubMed - indexed for MEDLINE]
4.
5.

Synthesis, in vitro aerobic and hypoxic cytotoxicity and radiosensitizing activity of novel metronidazole tethered 5-fluorouracil.

Abdi K, Khalaj A, Ostad SN, Lamei N, Khoshayand MR.

Daru. 2013 Dec 20;21(1):76. doi: 10.1186/2008-2231-21-76.

PMID:
24359860
[PubMed]
Free PMC Article
6.

Nitroimidazoles, XIV: Synthesis of 4-nitroimidazoles with 1-substituents containing acid, ester or phenol functions, and radiosensitizing efficiency of some of these compounds.

Suwinski J, Szczepankiewicz W, Widel M.

Arch Pharm (Weinheim). 1992 Jun;325(6):317-24.

PMID:
1444756
[PubMed - indexed for MEDLINE]
7.

Novel substituted (Z)-5-((N-benzyl-1H-indol-3-yl)methylene)imidazolidine-2,4-diones and 5-((N-benzyl-1H-indol-3-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones as potent radio-sensitizing agents.

Reddy YT, Sekhar KR, Sasi N, Reddy PN, Freeman ML, Crooks PA.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):600-2. doi: 10.1016/j.bmcl.2009.11.082. Epub 2009 Nov 22.

PMID:
20005706
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Radiosensitizing ability and cytotoxicity of some 5(4)-substituted 2-methyl-4(5)-nitroimidazoles.

Wideł M, Watras J, Suwiński J, Salwińska E.

Neoplasma. 1982;29(4):407-15.

PMID:
7133232
[PubMed - indexed for MEDLINE]
9.

Cytotoxicity and radiosensitising activity of synthesized dinitrophenyl derivatives of 5-fluorouracil.

Abdi K, Khalaj A, Ostad SN, Khoshayand MR.

Daru. 2012;20(1):3. doi: 10.1186/1560-8115-20-3. Epub 2012 Jul 19.

PMID:
23226112
[PubMed]
Free PMC Article
10.

[Synthesis and radiosensitizing activity of nitro-arylimino-diethyl-sodium thiosulfate and nitro phenylalanine derivatives].

Liu HX, Hu B, Li Z, Mi FS, Shen Y.

Yao Xue Xue Bao. 1992;27(8):632-7. Chinese.

PMID:
1481683
[PubMed - indexed for MEDLINE]
11.

Potent radiosensitizing agents: 5-methylselenyl- and 5-phenylselenyl-methyl-2'-deoxyuridine.

Rode AB, Kim BM, Park SH, Hong IS, Hong SH.

Bioorg Med Chem Lett. 2011 Feb 15;21(4):1151-4. doi: 10.1016/j.bmcl.2010.12.102. Epub 2010 Dec 25.

PMID:
21251826
[PubMed - indexed for MEDLINE]
12.

Synthesis of a series of nitrothiophenes with basic or electrophilic substituents and evaluation as radiosensitizers and as bioreductively activated cytotoxins.

Threadgill MD, Webb P, O'Neill P, Naylor MA, Stephens MA, Stratford IJ, Cole S, Adams GE, Fielden EM.

J Med Chem. 1991 Jul;34(7):2112-20.

PMID:
2066984
[PubMed - indexed for MEDLINE]
13.

Novel lipophilic hydroxyurea derivatives: synthesis, cytostatic and antiviral activity evaluations.

Perković I, Butula I, Zorc B, Hock K, Kraljević Pavelić S, Pavelić K, Clercq ED, Balzarini J, Mintas M.

Chem Biol Drug Des. 2008 Jun;71(6):546-53. doi: 10.1111/j.1747-0285.2008.00660.x. Epub 2008 Apr 10.

PMID:
18410308
[PubMed - indexed for MEDLINE]
14.

Synthesis of novel dioxane nucleosides having two bases, physico-chemical properties, and their biological activities.

Kajimoto N, Yamaizumi J, Aida M, Harada K, Maeda M.

Nucleic Acids Symp Ser. 1997;(37):5-6.

PMID:
9585971
[PubMed - indexed for MEDLINE]
15.

Toxicity of nitro compounds toward hypoxic mammalian cells in vitro: dependence on reduction potential.

Adams GE, Stratford IJ, Wallace RG, Wardman P, Watts ME.

J Natl Cancer Inst. 1980 Mar;64(3):555-60.

PMID:
6928241
[PubMed - indexed for MEDLINE]
16.

Radiosensitizing hypoxic cells with new 3-nitro-1,2,4-triazole derivatives in vitro and in vivo.

Nagao Y, Sano S, Ochiai M, Fuji K, Nishimoto S, Kagiya T, Murayama C, Mori T, Shibamoto Y, Sasai K, et al.

Chem Pharm Bull (Tokyo). 1989 Jul;37(7):1951-3.

PMID:
2805177
[PubMed - indexed for MEDLINE]
17.

[Experimental study of radiosensitizing effect of analogs of purines and pyrimidine bases in cultured HeLa cells].

Pavlov AS, Kostromina KN, Parkhomenko IM, Simakina EP, Han Youngsoo.

Vestn Ross Akad Med Nauk. 2001;(8):48-51. Russian.

PMID:
11552626
[PubMed - indexed for MEDLINE]
18.

Synthesis and biological evaluation of new 4beta-5-Fu-substituted 4'-demethylepipodophyllotoxin derivatives.

Zhang FM, Yao XJ, Tian X, Tu YQ.

Molecules. 2006 Nov 2;11(11):849-57.

PMID:
18007391
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

NLNQ-1, a 2-[3-(2-nitro-1-imidazolyl) propylamino]-3-chloro-1,4-naphthoquinone, as a hypoxia-selective cytotoxin and radiosensitizer.

Papadopoulou MV, Bloomer WD.

In Vivo. 2008 May-Jun;22(3):285-8.

PMID:
18610737
[PubMed - indexed for MEDLINE]
Free Article

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