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Items: 1 to 20 of 70

1.

A stability switch for proteins.

Clackson T.

Chem Biol. 2006 Sep;13(9):926-8.

2.

Precise control of protein concentration in living cells.

Lau HD, Yaegashi J, Zaro BW, Pratt MR.

Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8458-61. doi: 10.1002/anie.201003073. No abstract available.

PMID:
20878685
3.

Targeting protein stability with a small molecule.

Lampson MA, Kapoor TM.

Cell. 2006 Sep 8;126(5):827-9.

4.

Solution structure of the FK506-binding domain of human FKBP38.

Maestre-Martínez M, Edlich F, Jarczowski F, Weiwad M, Fischer G, Lücke C.

J Biomol NMR. 2006 Mar;34(3):197-202. No abstract available.

PMID:
16604427
5.

Controlling proteins the intein way.

Evanko D.

Nat Methods. 2007 Feb;4(2):112-3.

PMID:
17326269
6.

Regulating cell surface glycosylation with a small-molecule switch.

Dube DH, de Graffenried CL, Kohler JJ.

Methods Enzymol. 2006;415:213-29.

PMID:
17116477
7.

Engineering modular protein interaction switches by sequence overlap.

Sallee NA, Yeh BJ, Lim WA.

J Am Chem Soc. 2007 Apr 18;129(15):4606-11. Epub 2007 Mar 24.

PMID:
17381089
8.

In vitro selection of RNA aptamers against a composite small molecule-protein surface.

Plummer KA, Carothers JM, Yoshimura M, Szostak JW, Verdine GL.

Nucleic Acids Res. 2005 Sep 30;33(17):5602-10. Print 2005.

9.

Crystal structure of the FK506 binding domain of Plasmodium falciparum FKBP35 in complex with FK506.

Kotaka M, Ye H, Alag R, Hu G, Bozdech Z, Preiser PR, Yoon HS, Lescar J.

Biochemistry. 2008 Jun 3;47(22):5951-61. doi: 10.1021/bi800004u. Epub 2008 May 9.

PMID:
18465874
10.

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.

Vedadi M, Niesen FH, Allali-Hassani A, Fedorov OY, Finerty PJ Jr, Wasney GA, Yeung R, Arrowsmith C, Ball LJ, Berglund H, Hui R, Marsden BD, Nordlund P, Sundstrom M, Weigelt J, Edwards AM.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15835-40. Epub 2006 Oct 11.

11.

An FKBP destabilization domain modulates protein levels in Plasmodium falciparum.

Armstrong CM, Goldberg DE.

Nat Methods. 2007 Dec;4(12):1007-9. Epub 2007 Nov 11.

PMID:
17994030
12.

FKBP family proteins: immunophilins with versatile biological functions.

Kang CB, Hong Y, Dhe-Paganon S, Yoon HS.

Neurosignals. 2008;16(4):318-25. doi: 10.1159/000123041. Epub 2008 Jul 18. Review.

PMID:
18635947
13.

Accurate prediction of stability changes in protein mutants by combining machine learning with structure based computational mutagenesis.

Masso M, Vaisman II.

Bioinformatics. 2008 Sep 15;24(18):2002-9. doi: 10.1093/bioinformatics/btn353. Epub 2008 Jul 16.

14.

Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands.

Stankunas K, Bayle JH, Havranek JJ, Wandless TJ, Baker D, Crabtree GR, Gestwicki JE.

Chembiochem. 2007 Jul 9;8(10):1162-9.

PMID:
17525916
15.

Applications of site-specific chemical modification in the manufacture of biopharmaceuticals: I. An overview.

Lundblad RL, Bradshaw RA.

Biotechnol Appl Biochem. 1997 Dec;26 ( Pt 3):143-51. Review.

PMID:
9428153
16.

Fragment-based synthesis and SAR of modified FKBP ligands: influence of different linking on binding affinity.

Röhrig CH, Loch C, Guan JY, Siegal G, Overhand M.

ChemMedChem. 2007 Jul;2(7):1054-70.

PMID:
17541991
17.

A novel calmodulin-Ca2+ target recognition activates the Bcl-2 regulator FKBP38.

Edlich F, Maestre-Martínez M, Jarczowski F, Weiwad M, Moutty MC, Malesević M, Jahreis G, Fischer G, Lücke C.

J Biol Chem. 2007 Dec 14;282(50):36496-504. Epub 2007 Oct 17.

18.

Engineering of monomeric FK506-binding protein 22 with peptidyl prolyl cis-trans isomerase. Importance of a V-shaped dimeric structure for binding to protein substrate.

Budiman C, Bando K, Angkawidjaja C, Koga Y, Takano K, Kanaya S.

FEBS J. 2009 Aug;276(15):4091-101. doi: 10.1111/j.1742-4658.2009.07116.x. Epub 2009 Jun 25.

19.

Functional drift of sequence attributes in the FK506-binding proteins (FKBPs).

Galat A.

J Chem Inf Model. 2008 May;48(5):1118-30. doi: 10.1021/ci700429n. Epub 2008 Apr 16.

PMID:
18412331
20.

Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool.

Takakusagi Y, Kuramochi K, Takagi M, Kusayanagi T, Manita D, Ozawa H, Iwakiri K, Takakusagi K, Miyano Y, Nakazaki A, Kobayashi S, Sugawara F, Sakaguchi K.

Bioorg Med Chem. 2008 Nov 15;16(22):9837-46. doi: 10.1016/j.bmc.2008.09.061. Epub 2008 Sep 30.

PMID:
18930404
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