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Results: 1 to 20 of 147

1.

Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages.

Smith SJ, Fenwick PS, Nicholson AG, Kirschenbaum F, Finney-Hayward TK, Higgins LS, Giembycz MA, Barnes PJ, Donnelly LE.

Br J Pharmacol. 2006 Oct;149(4):393-404. Epub 2006 Sep 4.

PMID:
16953188
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Synergistic effects of p38 mitogen-activated protein kinase inhibition with a corticosteroid in alveolar macrophages from patients with chronic obstructive pulmonary disease.

Armstrong J, Harbron C, Lea S, Booth G, Cadden P, Wreggett KA, Singh D.

J Pharmacol Exp Ther. 2011 Sep;338(3):732-40. doi: 10.1124/jpet.111.180737. Epub 2011 May 24.

PMID:
21610141
[PubMed - indexed for MEDLINE]
Free Article
3.

Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage.

Tudhope SJ, Finney-Hayward TK, Nicholson AG, Mayer RJ, Barnette MS, Barnes PJ, Donnelly LE.

J Pharmacol Exp Ther. 2008 Jan;324(1):306-12. Epub 2007 Oct 5.

PMID:
17921189
[PubMed - indexed for MEDLINE]
Free Article
4.

p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism.

Meja KK, Seldon PM, Nasuhara Y, Ito K, Barnes PJ, Lindsay MA, Giembycz MA.

Br J Pharmacol. 2000 Nov;131(6):1143-53.

PMID:
11082122
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.

Cameron P, Smith SJ, Giembycz MA, Rotondo D, Plevin R.

Br J Pharmacol. 2003 Dec;140(7):1320-30. Epub 2003 Nov 3.

PMID:
14597601
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.

Koch A, Giembycz M, Ito K, Lim S, Jazrawi E, Barnes PJ, Adcock I, Erdmann E, Chung KF.

Am J Respir Cell Mol Biol. 2004 Mar;30(3):342-9. Epub 2003 Jul 18.

PMID:
12871851
[PubMed - indexed for MEDLINE]
8.

Resveratrol impairs the release of steroid-resistant inflammatory cytokines from human airway smooth muscle cells in chronic obstructive pulmonary disease.

Knobloch J, Sibbing B, Jungck D, Lin Y, Urban K, Stoelben E, Strauch J, Koch A.

J Pharmacol Exp Ther. 2010 Dec;335(3):788-98. doi: 10.1124/jpet.110.166843. Epub 2010 Aug 26.

PMID:
20801891
[PubMed - indexed for MEDLINE]
Free Article
9.

Inhibition of secretory phospholipase A2-induced cytokine production in human lung macrophages by budesonide.

Triggiani M, Granata F, Petraroli A, Loffredo S, Frattini A, Staiano RI, Monaco G, Marone G.

Int Arch Allergy Immunol. 2009;150(2):144-55. doi: 10.1159/000218117. Epub 2009 May 11.

PMID:
19439980
[PubMed - indexed for MEDLINE]
10.
11.

Corticosteroid effects on COPD alveolar macrophages: dependency on cell culture methodology.

Higham A, Lea S, Ray D, Singh D.

J Immunol Methods. 2014 Mar;405:144-53. doi: 10.1016/j.jim.2014.02.003. Epub 2014 Feb 12.

PMID:
24530567
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease.

Docena G, Rovedatti L, Kruidenier L, Fanning A, Leakey NA, Knowles CH, Lee K, Shanahan F, Nally K, McLean PG, Di Sabatino A, MacDonald TT.

Clin Exp Immunol. 2010 Oct;162(1):108-15. doi: 10.1111/j.1365-2249.2010.04203.x. Epub 2010 Aug 20.

PMID:
20731675
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The role of P38 MAPK and PKC in BLP induced TNF-alpha release, apoptosis, and NFkappaB activation in THP-1 monocyte cells.

O'Sullivan AW, Wang JH, Redmond HP.

J Surg Res. 2009 Jan;151(1):138-44. doi: 10.1016/j.jss.2008.02.031. Epub 2008 Mar 18.

PMID:
18675993
[PubMed - indexed for MEDLINE]
14.

KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.

Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst J, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ.

Eur J Pharmacol. 2010 Apr 25;632(1-3):93-102. doi: 10.1016/j.ejphar.2010.01.011. Epub 2010 Feb 2.

PMID:
20132813
[PubMed - indexed for MEDLINE]
15.

Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor.

Westra J, Doornbos-van der Meer B, de Boer P, van Leeuwen MA, van Rijswijk MH, Limburg PC.

Arthritis Res Ther. 2004;6(4):R384-92. Epub 2004 Jun 21.

PMID:
15225374
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor.

Schmeck B, Zahlten J, Moog K, van Laak V, Huber S, Hocke AC, Opitz B, Hoffmann E, Kracht M, Zerrahn J, Hammerschmidt S, Rosseau S, Suttorp N, Hippenstiel S.

J Biol Chem. 2004 Dec 17;279(51):53241-7. Epub 2004 Oct 13.

PMID:
15485852
[PubMed - indexed for MEDLINE]
Free Article
17.

Second-generation inhibitors demonstrate the involvement of p38 mitogen-activated protein kinase in post-transcriptional modulation of inflammatory mediator production in human and rodent airways.

Birrell MA, Wong S, McCluskie K, Catley MC, Hardaker EL, Haj-Yahia S, Belvisi MG.

J Pharmacol Exp Ther. 2006 Mar;316(3):1318-27. Epub 2005 Dec 20.

PMID:
16368902
[PubMed - indexed for MEDLINE]
Free Article
18.

Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo?

Page TH, Brown A, Timms EM, Foxwell BM, Ray KP.

Arthritis Rheum. 2010 Nov;62(11):3221-31. doi: 10.1002/art.27631.

PMID:
20589681
[PubMed - indexed for MEDLINE]
Free Article
19.

SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence.

Underwood DC, Osborn RR, Kotzer CJ, Adams JL, Lee JC, Webb EF, Carpenter DC, Bochnowicz S, Thomas HC, Hay DW, Griswold DE.

J Pharmacol Exp Ther. 2000 Apr;293(1):281-8.

PMID:
10734180
[PubMed - indexed for MEDLINE]
Free Article
20.

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