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Results: 1 to 20 of 110

1.

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C.

Nat Immunol. 2006 Oct;7(10):1048-56. Epub 2006 Sep 3.

PMID:
16951689
[PubMed - indexed for MEDLINE]
2.

Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.

Scheller M, Huelsken J, Rosenbauer F, Taketo MM, Birchmeier W, Tenen DG, Leutz A.

Nat Immunol. 2006 Oct;7(10):1037-47. Epub 2006 Sep 3.

PMID:
16951686
[PubMed - indexed for MEDLINE]
3.

Activation of CCAAT/enhancer-binding protein alpha or PU.1 in hematopoietic stem cells leads to their reduced self-renewal and proliferation.

Fukuchi Y, Ito M, Shibata F, Kitamura T, Nakajima H.

Stem Cells. 2008 Dec;26(12):3172-81. doi: 10.1634/stemcells.2008-0320. Epub 2008 Sep 11.

PMID:
18787208
[PubMed - indexed for MEDLINE]
Free Article
4.

Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiation.

Tarafdar A, Dobbin E, Corrigan P, Freeburn R, Wheadon H.

PLoS One. 2013 Nov 26;8(11):e81030. doi: 10.1371/journal.pone.0081030. eCollection 2013.

PMID:
24324557
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.

Perry JM, He XC, Sugimura R, Grindley JC, Haug JS, Ding S, Li L.

Genes Dev. 2011 Sep 15;25(18):1928-42. doi: 10.1101/gad.17421911. Epub 2011 Sep 2.

PMID:
21890648
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity.

Trowbridge JJ, Guezguez B, Moon RT, Bhatia M.

Stem Cells. 2010 Aug;28(8):1379-89. doi: 10.1002/stem.457.

PMID:
20521329
[PubMed - indexed for MEDLINE]
Free Article
7.

Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.

Seo E, Basu-Roy U, Zavadil J, Basilico C, Mansukhani A.

Mol Cell Biol. 2011 Nov;31(22):4593-608. doi: 10.1128/MCB.05798-11. Epub 2011 Sep 19.

PMID:
21930787
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.

Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, Kuttler F, Malanchi I, Birchmeier W, Leutz A, Huelsken J, Held W.

Blood. 2008 Jan 1;111(1):142-9. Epub 2007 Sep 28.

PMID:
17906078
[PubMed - indexed for MEDLINE]
Free Article
9.

MOZ is essential for maintenance of hematopoietic stem cells.

Katsumoto T, Aikawa Y, Iwama A, Ueda S, Ichikawa H, Ochiya T, Kitabayashi I.

Genes Dev. 2006 May 15;20(10):1321-30.

PMID:
16702405
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.

Hu Z, Negrotto S, Gu X, Mahfouz R, Ng KP, Ebrahem Q, Copelan E, Singh H, Maciejewski JP, Saunthararajah Y.

Mol Cancer Ther. 2010 Jun;9(6):1536-43. doi: 10.1158/1535-7163.MCT-10-0191. Epub 2010 May 25.

PMID:
20501800
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Enforced activation of STAT5A facilitates the generation of embryonic stem-derived hematopoietic stem cells that contribute to hematopoiesis in vivo.

Schuringa JJ, Wu K, Morrone G, Moore MA.

Stem Cells. 2004;22(7):1191-204.

PMID:
15579639
[PubMed - indexed for MEDLINE]
Free Article
12.

Canonical Wnt pathway signaling suppresses VCAM-1 expression by marrow stromal and hematopoietic cells.

Malhotra S, Kincade PW.

Exp Hematol. 2009 Jan;37(1):19-30. doi: 10.1016/j.exphem.2008.08.008. Epub 2008 Oct 25.

PMID:
18951693
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation.

Luis TC, Weerkamp F, Naber BA, Baert MR, de Haas EF, Nikolic T, Heuvelmans S, De Krijger RR, van Dongen JJ, Staal FJ.

Blood. 2009 Jan 15;113(3):546-54. doi: 10.1182/blood-2008-06-163774. Epub 2008 Oct 2.

PMID:
18832654
[PubMed - indexed for MEDLINE]
Free Article
14.

Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.

Buono M, Visigalli I, Bergamasco R, Biffi A, Cosma MP.

J Exp Med. 2010 Aug 2;207(8):1647-60. doi: 10.1084/jem.20091022. Epub 2010 Jul 19.

PMID:
20643830
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML.

Jamieson CH, Ailles LE, Dylla SJ, Muijtjens M, Jones C, Zehnder JL, Gotlib J, Li K, Manz MG, Keating A, Sawyers CL, Weissman IL.

N Engl J Med. 2004 Aug 12;351(7):657-67.

PMID:
15306667
[PubMed - indexed for MEDLINE]
Free Article
16.

Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.

Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A.

Cell Stem Cell. 2010 Mar 5;6(3):279-86. doi: 10.1016/j.stem.2010.01.005.

PMID:
20207230
[PubMed - indexed for MEDLINE]
Free Article
17.

Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors.

Baba Y, Garrett KP, Kincade PW.

Immunity. 2005 Dec;23(6):599-609.

PMID:
16356858
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation.

Chiba T, Zheng YW, Kita K, Yokosuka O, Saisho H, Onodera M, Miyoshi H, Nakano M, Zen Y, Nakanuma Y, Nakauchi H, Iwama A, Taniguchi H.

Gastroenterology. 2007 Sep;133(3):937-50. Epub 2007 Jun 20.

PMID:
17673212
[PubMed - indexed for MEDLINE]
19.

HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche.

Jackson M, Axton RA, Taylor AH, Wilson JA, Gordon-Keylock SA, Kokkaliaris KD, Brickman JM, Schulz H, Hummel O, Hubner N, Forrester LM.

Stem Cells. 2012 Feb;30(2):150-60. doi: 10.1002/stem.782. Erratum in: Stem Cells. 2012 Jun;30(6):1311-2.

PMID:
22084016
[PubMed - indexed for MEDLINE]
Free Article
20.

NF-Y is necessary for hematopoietic stem cell proliferation and survival.

Bungartz G, Land H, Scadden DT, Emerson SG.

Blood. 2012 Feb 9;119(6):1380-9. doi: 10.1182/blood-2011-06-359406. Epub 2011 Nov 9.

PMID:
22072554
[PubMed - indexed for MEDLINE]
Free PMC Article

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