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Items: 1 to 20 of 352

1.

Fmr1 knockout mice are impaired in a leverpress escape/avoidance task.

Brennan FX, Albeck DS, Paylor R.

Genes Brain Behav. 2006 Aug;5(6):467-71.

2.

Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins.

Spencer CM, Serysheva E, Yuva-Paylor LA, Oostra BA, Nelson DL, Paylor R.

Hum Mol Genet. 2006 Jun 15;15(12):1984-94. Epub 2006 May 4.

3.

Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome.

Spencer CM, Alekseyenko O, Serysheva E, Yuva-Paylor LA, Paylor R.

Genes Brain Behav. 2005 Oct;4(7):420-30.

4.

Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation.

Qin M, Kang J, Smith CB.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15758-63. Epub 2002 Nov 11.

5.

Protective effects of melatonin against oxidative stress in Fmr1 knockout mice: a therapeutic research model for the fragile X syndrome.

Romero-Zerbo Y, Decara J, el Bekay R, Sanchez-Salido L, Del Arco-Herrera I, de Fonseca FR, de Diego-Otero Y.

J Pineal Res. 2009 Mar;46(2):224-34. doi: 10.1111/j.1600-079X.2008.00653.x. Epub 2008 Dec 23.

PMID:
19141086
6.

The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments in Fmr1 KO mice.

Vinueza Veloz MF, Buijsen RA, Willemsen R, Cupido A, Bosman LW, Koekkoek SK, Potters JW, Oostra BA, De Zeeuw CI.

Genes Brain Behav. 2012 Apr;11(3):325-31. doi: 10.1111/j.1601-183X.2011.00763.x. Epub 2012 Jan 19.

7.

Male and female Fmr1 knockout mice on C57 albino background exhibit spatial learning and memory impairments.

Baker KB, Wray SP, Ritter R, Mason S, Lanthorn TH, Savelieva KV.

Genes Brain Behav. 2010 Aug;9(6):562-74. doi: 10.1111/j.1601-183X.2010.00585.x. Epub 2010 Apr 6.

8.

A phenotypic and molecular characterization of the fmr1-tm1Cgr fragile X mouse.

Yan QJ, Asafo-Adjei PK, Arnold HM, Brown RE, Bauchwitz RP.

Genes Brain Behav. 2004 Dec;3(6):337-59.

9.

Downregulation of tonic GABAergic inhibition in a mouse model of fragile X syndrome.

Curia G, Papouin T, Séguéla P, Avoli M.

Cereb Cortex. 2009 Jul;19(7):1515-20. doi: 10.1093/cercor/bhn159. Epub 2008 Sep 11.

10.
11.

Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes.

Musumeci SA, Calabrese G, Bonaccorso CM, D'Antoni S, Brouwer JR, Bakker CE, Elia M, Ferri R, Nelson DL, Oostra BA, Catania MV.

Exp Neurol. 2007 Jan;203(1):233-40. Epub 2006 Sep 27.

PMID:
17007840
12.

Alterations in the auditory startle response in Fmr1 targeted mutant mouse models of fragile X syndrome.

Nielsen DM, Derber WJ, McClellan DA, Crnic LS.

Brain Res. 2002 Feb 8;927(1):8-17.

PMID:
11814427
13.

A mouse model of fragile X syndrome exhibits heightened arousal and/or emotion following errors or reversal of contingencies.

Moon J, Ota KT, Driscoll LL, Levitsky DA, Strupp BJ.

Dev Psychobiol. 2008 Jul;50(5):473-85. doi: 10.1002/dev.20308.

PMID:
18551464
14.

Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex.

Ventura R, Pascucci T, Catania MV, Musumeci SA, Puglisi-Allegra S.

Behav Pharmacol. 2004 Sep;15(5-6):433-42.

PMID:
15343070
15.

Mouse model of fragile X syndrome: behavioral and hormonal response to stressors.

Nielsen DM, Evans JJ, Derber WJ, Johnston KA, Laudenslager ML, Crnic LS, Maclean KN.

Behav Neurosci. 2009 Jun;123(3):677-86. doi: 10.1037/a0015242.

PMID:
19485574
16.

Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome.

Dickson PE, Corkill B, McKimm E, Miller MM, Calton MA, Goldowitz D, Blaha CD, Mittleman G.

Behav Brain Res. 2013 Sep 1;252:126-35. doi: 10.1016/j.bbr.2013.05.060. Epub 2013 Jun 4.

17.

Dendritic spine abnormalities in the occipital cortex of C57BL/6 Fmr1 knockout mice.

McKinney BC, Grossman AW, Elisseou NM, Greenough WT.

Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5;136B(1):98-102.

PMID:
15892134
18.

Corticosterone response to acute stress in a mouse model of Fragile X syndrome.

Markham JA, Beckel-Mitchener AC, Estrada CM, Greenough WT.

Psychoneuroendocrinology. 2006 Jul;31(6):781-5. Epub 2006 Apr 18.

PMID:
16621323
19.

Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits.

Uutela M, Lindholm J, Louhivuori V, Wei H, Louhivuori LM, Pertovaara A, Akerman K, Castrén E, Castrén ML.

Genes Brain Behav. 2012 Jul;11(5):513-23. doi: 10.1111/j.1601-183X.2012.00784.x. Epub 2012 Apr 11.

20.

Chronic metabotropic glutamate receptor 5 inhibition corrects local alterations of brain activity and improves cognitive performance in fragile X mice.

Michalon A, Bruns A, Risterucci C, Honer M, Ballard TM, Ozmen L, Jaeschke G, Wettstein JG, von Kienlin M, Künnecke B, Lindemann L.

Biol Psychiatry. 2014 Feb 1;75(3):189-97. doi: 10.1016/j.biopsych.2013.05.038. Epub 2013 Jul 30.

PMID:
23910948
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